Propofol

Maintenance Anesthesia CRI Infusions

Kilogram based calculations (with pounds/kilogram converter)
© Robert M. Stein, DVM, PC

Patient Name Date 3/12/2011

Patient Wt. 34.5 kgs Lean body estimate

Propofol dose rate 0.017 mg/kg/min = 1 mg/kg/hr = 3.45 ml/hr

Propofol dose rate 0.033 mg/kg/min = 2 mg/kg/hr = 6.90 ml/hr

Propofol dose rate 0.050 mg/kg/min = 3 mg/kg/hr = 10.35 ml/hr

Propofol dose rate 0.067 mg/kg/min = 4 mg/kg/hr = 13.80 ml/hr

Propofol dose rate 0.083 mg/kg/min = 5 mg/kg/hr = 17.25 ml/hr

Propofol dose rate 0.100 mg/kg/min = 6 mg/kg/hr = 20.70 ml/hr

Propofol dose rate 0.117 mg/kg/min = 7 mg/kg/hr = 24.15 ml/hr

Drug CRI Dose Range

PROPOFOL - 1 to 7 mg/kg/hr (0.017 to 0..117 mg/kg/min)
Suggested starting maintenance dose rate is 4 to 5 mg/kg/hr. Induction should be with propofol when propofol
maintenance anesthesia is planned. Otherwise, relatively higher initial drug dose rates will be required.

Drug Concentration
PROPOFOL - 10 mg/ml

Precautions
1) Change extension sets between patients.
2) Discard unused drug 12 hours after opening. Discard any contaminated drug.

Weight Converter
For those that prefer to weigh in pounds. You will need to manually transfer the patient weight in kilograms into the patient weight field
above - it will not be transferred automatically.

Enter patient weight in pounds 45 lbs = 20.5 kgs

Drip Rate Converter

Propofol CRI rate from above 24.6 ml/hr Manual entry required
Drip set (drops/ml) 60 drops/ml Manual entry required
Drops per second 0.41 drops/sec
Seconds per drop 2.44 sec/drop