Professional Documents
Culture Documents
Zarg
4 Basic
of
pelvis
PERINEUM
¢ Perineum is the thin layer of skin between vaginal opening or scrotum and anus.
¢ It consists of tissue that makes up the bottom of the pelvic cavity (common site for
tears during childbirth).
¢ The area inferior to the pelvic diaphragm can be divided into:
• anterior urogenital triangle (pierced by the vagina and the urethra)
• posterior anal triangle.
¢ The superficial and deep perineal fascias are continuous with the labia majora and
are attached:
• anteriorly to the pubic symphysis
• laterally to the body of the pubis.
• The superficial perineal muscles are:
• superficial transverse perineus
s
• ischiocavernosus
• bulbocavernosus
petae
! The positions of the sutures and fontanelles play a
FETAL HEAD very important role in identifying the position of the
-Made up of 5 main bones: two parietal bones, two frontal bones, and the occipital
bone.
-These are held together by sutures, which permit movement during birth:
• The coronal suture
• The lambdoid suture
• The frontal suture
-When two or more sutures meet, there is an irregular membranous area between them
called a fontanelle.
• The anterior fontanelle or bregma.
• The posterior fontanelle or the lambda.
¢ Regions of the fetal head:
• The occiput The degree of moulding can be assessed vaginally:
• No moulding: when the suture lines are separate.
• The vertex • 1+ moulding: when the suture lines meet.
• 2+ moulding: when the bones overlap but can be reduced with gentle digital
• The bregma pressure.
• 3+ moulding: when the bones overlap and are irreducible with gentle digital
• The sinciput pressure.
PRECONCEPTION COUNSELLING
¢ It is a visit with a healthcare provider where the patient discuss many aspects of pregnancy
and plan for a healthy pregnancy.
¢ Preconception counselling should be offered to:
• optimize maternal cardiovascular status (may involve surgery)
• modify medication
• discuss maternal and fetal risks of pregnancy.
¢During preconception counselling the following topics are discussed:
• Family history
•General medical history
•OB/GYN history
•Lifestyle
•Vaccination
¢Physical examination and lab tests
TERATOGENESIS:
¢ Teratogenesis is a prenatal toxicity characterized by structural or functional defects in
the developing embryo or fetus.
¢ Teratogens are substances that cause congenital disorders in a developing embryo or
fetus.
¢ A teratogen is anything a person is exposed to or ingests during pregnancy that’s
known to cause fetal abnormalities.
¢ Drugs, medicine, chemicals, certain infections and toxic substances are examples of
teratogens. Teratogens can also increase the risk for miscarriage, preterm, labor or
stillbirth.
¢ The following factors determine how dangerous teratogen exposure is during
pregnancy:
• The drug, substance or type of toxin.
• How long the pregnant person was exposed.
• The amount of exposure (dosage or quantity).
• The gestational age of the fetus (weeks of pregnancy) at exposure.
• Hereditary factors that could increase the fetus’s risk
The most common position is left mentoanterior (LMA)—As the ROP position is 5 times more common
than LOP and as the conversion of face occurs from deflexed OP, LMA is the commonest. Overall anterior
positions are more frequent than the posterior one.
Mechanism of Labour in Face Position
Mentoanterior 60–80% (LMA or RMA)
The principal movements are like those of corresponding occipitoanterior position. The exceptions are
increasing extension instead of flexion and delivery by flexion instead of extension of the head.
Engagement: The diameter of engagement is the oblique diameter—right in LMA, left in RMA, with
the mentum related to one iliopubic eminence and the glabella to the opposite sacroiliac joint. The
engaging diameter of the head is submentobregmatic 9.5 cm (3 3/4") in fully extended head or
submentovertical 11.5 cm (4 1/2") in partially extended head. Engagement is delayed because of long
distance between the mentum and biparietal plane (7 cm). Descent with increasing extension occurs till
the chin touches the pelvic floor.
Internal rotation—Internal rotation of the chin occurs through 1/8th of a circle anteriorly, placing the
mentum behind the symphysis pubis. Further descent occurs till the submentum hinges under the pubic
arch.
Delivery of the head—The head is born by flexion delivering the chin, face, brow, vertex and lastly the
occiput. The diameter distending the vulval outlet is submentovertical—11.5 cm (4 1/2"). Restitution
occurs through 1/8th of a circle opposite to the direction of internal rotation. External rotation occurs
further 1/8th of circle to the same side of restitution so that ultimately the face looks directly to the left
thigh in LMA and right thigh in RMA. This follows delivery of the anterior shoulder followed by the
posterior shoulder and the rest of the trunk by lateral flexion.
12-Mechanism of Labour in Brow Presentation
Brow is the rarest variety of cephalic presentation where the presenting part is the brow and the attitude of the
head is short that of degree of extension necessary to produce face presentation, i.e. the head lies in between
full flexion and full extension. The denominator is the fore head
Mechanism of Labor in Brow Position
Typically converts to either a vertex or face presentation, but, if persistent, may cause dystocia requiring
caesarean delivery.
Diameter of engagement is through the oblique diameter with the brow anterior or posterior. As the engaging
diameter of the head is mentovertical (14 cm), there is no mechanism of labor in an average size baby with
normal pelvis. However, if the baby is small and the pelvis is roomy with good uterine contractions, delivery
can occur in mentoanterior brow position. The brow descends until it touches the pelvic floor. Internal
rotation and descent occur till the root of the nose hinges under the symphysis pubis. The brow and the vertex
are delivered by flexion followed by extension to deliver the face. The mechanism is more or less the same as
face-to-pubis delivery. Usual restitution and external rotation occur. There is no mechanism in posterior brow
position
13-Mechanism of Labour in Breech Presentation
In breech presentation, the lie is longitudinal and the podalic pole presents at the pelvic brim
There are two varieties of breech presentation:
Complete (flexed breech): Thighs are flexed at hips and legs at knees. The presenting part consists of
two buttocks, external genitalia and two feet. It is commonly present in multi-parae
Incomplete: This is due to varying degrees of extension of thighs or legs at the podalic pole.
Breech with extended legs (Frank breech): In this condition, thighs are flexed on the trunk and legs
are extended at the knee joints. The presenting part consists of the two buttocks and external genitalia
only. It is commonly present in primigravidae due to a tight abdominal wall, good uterine tone and
early engagement of breech.
Footling presentation: Both thighs and legs are partially extended bringing the legs to present at
brim.
Knee presentation: Thighs are extended but the knees are flexed, bringing the knees down to present
at the brim.
Positions
Sacrum is the denominator of breech and there are four positions. In anterior positions, sacrum is
directed toward iliopubic eminences and in posterior positions, sacrum is directed to sacroiliac joints.
The positions are:
Left Sacroanterior (LSA): the most common
Right Sacroanterior (RSA
Right Sacroposterior (RSP)
Left Sacroposterior (LSP).
Mechanism of Labor in Breech Presentation
The principal movements occur at three places:
Buttocks:
The diameter of engagement of the buttock is one of the oblique diameters of the inlet. The
engaging diameter is bitrochanteric (10 cm or 4") with the sacrum directed toward the iliopubic
eminence. When the diameter passes through the pelvic brim, the breech is engaged.
Descent of the buttocks occurs until the anterior buttock touches the pelvic floor.
Internal rotation of the anterior buttock occurs through 1/8th of a circle placing it behind the
symphysis pubis.
Further descent with lateral flexion of the trunk occurs until the anterior hip hinges under the
symphysis pubis which is released first followed by the posterior hip.
Delivery of the trunk and the lower limbs follow.
Restitution occurs so that the buttocks occupy the original position as during engagement in oblique
diameter.
Shoulders
Bisacromial diameter (12 cm or 4 3/4") engages in the same oblique diameter as that occupied by
the buttocks at the brim soon after the delivery of the breech.
Descent occurs with internal rotation of the shoulders bringing the shoulders to lie in the
anteroposterior diameter of the pelvic outlet. The trunk simultaneously rotates externally through
1/8th of a circle.
Delivery of the posterior shoulder followed by the anterior one is completed by anterior flexion of
the delivered trunk.
Restitution and external rotation: Untwisting of the trunk occurs putting the anterior shoulder
toward the right thigh in LSA and left thigh in RSA. External rotation of the shoulders occurs to the
same direction because of internal rotation of the occiput through 1/8th of a circle anteriorly. The fetal
trunk is now positioned as dorsoanterior.
Head
Engagement occurs either through the opposite oblique diameter as that occupied by the buttocks or
through the transverse diameter. The engaging diameter of the head is suboccipitofrontal (10 cm).
Descent with increasing flexion occurs.
Internal rotation of the occiput occurs anteriorly, through 1/8th or 2/8th of a circle placing the
occiput behind the symphysis pubis.
Further descent occurs until the subocciput hinges under the symphysis pubis.
Head is born by flexion—chin, mouth, nose, forehead, vertex and occiput appearing successively.
The expulsion of the head from the pelvic cavity depends entirely upon the bearing-down efforts and
not at all on uterine contractions.
14. Amnioscopy test to check if the baby has a
To examine the amniotic fluid genetic or chromosomal
and the fetus through the cervical anomaly.
canal after dilation of the cervix.
Procedure:
Conditions: 1. Done by using a needle,
1. fetus should be at term placed into a pocket of
2. the cervix must be open, amniotic fluid, under
3. the membrane should be non- direct ultrasound
rupture guidance
4. the baby should be alive 2. Aspirating amniotic fluid
containing desquamated
Procedure: living cells (amniocytes)
1. Patient in lithotomy position 3. Performed after 15 weeks
2. Speculum is applied without anesthesia.
3. Amnioscope inserted through the Indications:
vagina and the cervix (when it’s 1. Risk of a malformation,
dilated) check the karyotype
4. Obturator is removed. That light (chromosomes) and the DNA
will be on, so we can see the of the fetus, because amniotic
amniotic fluid through the fluid contains fetal cells.
amniotic sac which is intact and 2. Age older than 35 years
part of the fetus is presenting. 3. If there is prematurity risk,
check the fetal lung maturity
Results: by measuring the Lecithin-
1- Yellow - indicates bilirubin sphingomyelin ratio which is
2- Green - indicates meconium, supposed to be > 2. (if the
which leads to fetal distress. lungs are immature and we
3- Reddish - indicates death want to deliver the fetus as
soon as possible then we
Indications: have to give glucocorticoids.
1- If the mother is Rh - Examples: Betamethasone
2- Suspected fetal death 12mg/12h for 24hours (it’s
3- Used when the pregnancy better because it acts faster)
extends approximately 2 or Dexamethasone 6mg/12h
weeks after term. for 2 days.
4. Treatment in case of
Contraindications: polyhydramnios.
1- Active labor 5. Check for Rh
2- Ruptured membranes isoimmunization. We can see
3- Cervical infections if there is a reaction between
4- Unexplained vaginal bleeding the mother and fetus by
5- Closed cervix bilirubin which can be seen
in the amniotic fluid after
week 24.
15. Amniocentesis Complications:
16-Clinical and Laboratory Diagnosis of the Membrane Ruptures
PROM (Premature rupture of the membranes) is defined as amniorrhexis prior to the onset of labor at any
stage of gestation. Amniorrhexis means spontaneous rupture of membranes as opposed to amniotomy
PPROM is used to defined that the patient who are preterm with ruptured membranes, whether or not they
have contractions
Diagnosis
It is based on the history of vaginal loss of fluid and confirmation of amniotic fluid in the vaginal
A sterile vaginal speculum examination should be performed
Before labor, vaginal examination should not be performed
Carry out a complete ultrasonic examination
Confirmation of the diagnosis can be made by:
Testing the fluid with nitrazine paper, which will turn blue in the presence of the alkaline amniotic
fluid
Placing a sample on a microscopic slide, air drying, and examining for ferning
17-Clinical and Laboratory Diagnosis of the Fetal Distress
Fetal distress is an ill-defined term, used to express intrauterine fetal jeopardy, a result of intrauterine
fetal hypoxia. Nonreassuring fetal status (NRFS) is characterized by tachycardia or bradycardia, reduced
FHR variability, decelerations and absence of accelerations (spontaneous or elicited). It must be
emphasized that hypoxia and acidosis is the ultimate result of the many causes of intrauterine fetal
compromise.
FHR patterns in labor are dynamic and can change rapidly from normal to abnormal and vice versa.
Because of this uncertainty about the diagnosis of fetal distress, terminologies used are ―Reassuring‖ and
―Nonreassuring‖.
Nonreassuring fetal heart rate pattern is associated with fetal hypoxia, acidosis and therefore called fetal
distress.
Features to rule out metabolic acidosis are:
Presence of accelerations
Moderate variability
Scalp blood pH > 7.25.
Etiology
➢ Labor induction is when a pregnancy care provider starts labor instead of letting
labor starts on its own. Normally, they wait until 39 weeks to start a labor but
when fetus in risk , they can do it before 39 weeks.
Ways of to do labor;
1) Administration of medication to soften,thin and open(dilate) your cervix to prepare
it for birth.(Oxytocin)
2) Rupture the amniotic sac or break your water with a device
3) Medications to cause contractions (Prostaglandins ripen the cervix and induce
uterine contractions)
4) Cervical ripening balloon.( The balloon puts pressure on the inside of your cervix to
allow it to slowly open. The balloon will fall out once your cervix has opened enough
(about 4 cm), or it will be removed after about 12 hours.)
Management of stages;
1)First stage;
o Analgesia upon request
o Fetal heart monitoring and determine fetal position with examination
o Regular assessment of cervical dilation and fetal head
2) Second stage
o Warm compression, helping mother for safe and comfortable position
o Guide delivery of fetus through vaginal canals
o Cord clamping
3)Third stage
o Oxytocin administration after cutting umbilical cord to reduce blood loss with
strong contractions
o Examine placenta, umbilical cord , amniotic membranes, blood vessels to confirm
completeness
o Repair any obstetric lacerations
4)Stage Four
o Monitoring to rule out postpartum hemorrhage or preeclampsia
Ticket 21
Episiotomy and Perineum repair
Risks ;
Perineum Repair
There are four degrees of tears that can occur during delivery:
• First degree tears involve the vaginal mucosa and connective tissue; most of them close
spontaneously
• Second degree tears involve the vaginal mucosa, connective tissue and underlying muscles.
requires one or two sutures
• Third degree tears involve complete transection of the anal sphincter.
• Fourth degree tears involve the rectal mucosa.
Third and fourth they need anesthesia. Close the rectum with inverted stiches, and then we suture the
sphincter and the muscle layer, followed by the skin and mucosa, Rectum > anus >muscle>mucosa
Ticket 22 – 23
3rd Stage
4th Stage
1) Post-partum hemorrhage, which can be because of:
- Abnormal placental insertion
- Partially separated placenta (some of the placenta is inserted in the uterine
wall
- Hypotonic uterus (less contration)
- Retained placenta (placenta is separated fron the uterine wall, but remains
inside of the uterine cavity
2) Perineum rupture
Procedure: a hand is introduced inside the uterine cavity and with the fingers/cubital side of
hand, we remove the placenta.
1) Brandt-Andrew maneuver:We press in front or just over the symphysis and with
pulling of the umbilical cord. It is done only if placenta is separated from the uterine
wall.
2) Crede maneuver= placing a hand on the abdominal wall near the uterine fundus and
squeezing the uterine fundus between the thumb and finger
3) Controlled cord traction (CCT) is applied to the umbilical cord once the woman's
uterus has contracted after the birth of her baby, and her placenta is felt to have
separated from the uterine wall, whilst pressure is applied to her uterus beneath her
pubic bone until her placenta delivers.
25. Manual and instrumental curettage of the uterine cavity
▪ Health care providers perform dilation and curettage to diagnose and treat certain
uterine conditions — such as heavy bleeding — or to clear the uterine lining after a
miscarriage or abortion.
• Curettage = refers to the scraping or removal of tissue lining the uterine cavity
(endometrium) with a surgical instrument called a curette.
3)Treat excessive bleeding after delivery by clearing out any placenta that remains in
the uterus
2)An intravenous (IV) line may be started in your arm or hand and A urinary catheter
may be inserted.
3)Your doctor will insert an instrument called a speculum into your vagina to spread the
walls of the vagina apart to expose the cervix and cervix may be cleansed with an
antiseptic solution
4)Focal /local or generalized anesthesia will be done , determine the length of uterus
with instrument. A type of forceps, called a tenaculum, may be used to hold the cervix
steady for the procedure.
5) The cervix will be dilated by inserting a series of thin rods. Each rod will be larger in
diameter than the previous one. This process will gradually enlarge the opening of the
cervix so that the curette (spoon-shaped instrument) can be inserted.
6) The curette will be inserted through the cervical opening into the uterus , to scrape
away the tissues. In some cases, suction may be used to remove tissues. If you have
local anesthesia, this may cause cramping.
• Instrumental curettage = The curette will be inserted through the cervical opening into
the uterus and the sharp spoon-shaped edges will be passed across the lining of the
uterus to scrape away the tissues.
Risk factors ; Perforation of uterus, Infection, damage to cervix
Treatment
Tumors: Surgical resection
Premature ovarian failure: combined oral contraceptives
35. Cervical & Endometrial Neoplasm – Screening, HPV – DNA testing
HPV- CIN, Pap smear A screening test for cervical cancer in which cells
collected from the cervix are tested for infection with
Screening high-risk HPV types
For average-risk patients (asymptomatic,
Primary HPV test
immunocompetent, and normal cervical cancer
- Preferred cervical cancer screening test
screening history), they include three screening
strategies depending on age: Co-test (with concurrent Pap smear)
- Used when primary HPV tests are not available
- 21–29 years of age: Pap smear every 3 years
- The sample obtained for the Pap smear can also
- 30–65 years of age any of the following:
be used for DNA testing.
Pap smear every 3 years
HPV DNA testing every 5 years
Pap smear with HPV DNA testing every 5 years
Reflex HPV test (triage HPV test)
HPV – CIN - A test used to detect the DNA of high-risk HPV
Cervical intraepithelial neoplasia (CIN) types
Precursor lesion characterized by epithelial dysplasia - Performed after an abnormal Pap smear,
that begins at the basal layer of the squamocolumnar typically using the same Pap smear sample
junction and extends outward showing abnormal cells
May progress to invasive carcinoma if left untreated
Screening interval: perform every 5 years with HPV
Classification: classified as ClN I–III primary test and co-test
CIN I:
- mild dysplasia, involves ∼ ⅓ of the basal epithelium PAP smear
- Koilocytes may be present Description: a cytological screening test for cervical
- Epithelial cells with perinuclear halos cancer in which a cell sample taken from the cervix is
- Pathognomonic for HPV infection examined for cellular abnormalities that may be
indicative of cervical cancer
CIN II:
- moderate dysplasia, involves ⅓–⅔ of basal epithelium
Technique:
- Loss of epithelial architecture into as far as the middle
- To obtain the specimen, use a sterile speculum to
third of the epithelium
visualize the cervix
- Koilocytes may be present.
- Cleanse the cervix using a cotton pledget.
CIN III: - Visualize the transformation zone and, if possible, the
- severe, irreversible dysplasia or carcinoma in situ, squamocolumnar junction.
involves > ⅔ of basal epithelium - The specimen must be collected using a spatula or
- Loss of organized epithelial architecture brush that is rotated by 360 degrees.
- Koilocytes may be present. - Scraping of ectocervix
- Scraping of endocervix
- A thin layer of the specimen is uniformly applied to
the labelled glass slide.
- Immediate fixation
- Using 95% ethyl alcohol (or spray fixative) to avoid
drying
- Hold the fixative spray 15–20 cm away from the slide
and spray evenly.
- Stain using Papanicolaou dye.
36. Vaginal Smear 38. Lahm-Schiller test
Smear taken from the vaginal mucosa for cytological Medical test in which iodine solution is applied to the
analysis it is used to find the cause of vaginitis or cervix in order to diagnose cervical cancer.
vulvitis
-Procedure: Schiller's iodine solution is applied to the
Indications:
cervix under direct vision. Normal cervical mucosa
- May be considered in case of vaginitis symptoms such
contains glycogen and stains brown, whereas abnormal
as: vaginal itching, burning, rash, odour, or discharge
areas, such as early cervical cancer, do not take up the
- It may assist in suspicion of vaginal yeast infection,
stain.
trichomoniosis, and bacterial vaginosis
-The abnormal areas can then be biopsied and examined
Method histologically.
- Is not done during menstrual period, because -Schiller's test is not specific for cervical cancer, as
menstrual blood can affect the results areas of inflammation, ulceration and keratosis may also
- Vaginal irrigation, tampon use or sex (disrupting the not take up the stain.
pH) should be avoided for 24 hours before the test
- Antibiotics treatment is not administered at least 8 39. Biopsy
days before. A cervical biopsy is usually done when abnormalities
- The sampling is done with the patient in lithotomy are found during a pelvic exam, Pap smear, and/or HPV
position. test. It is often performed as part of a colposcopy.
- A speculum is used to facilitate use of a swab or
spatula to sample fluid inside the vagina. Types
- The sampling procedure may cause some discomfort Punch biopsy
and minor bleeding, but otherwise there are no - A small piece of cervical tissue (diameter < 5 mm) is
associated risks. removed by a circular blade.
- The sample is then smeared upon a microscope slide *Indication: Acetowhite area seen during colposcopy
and is observed by wet mount microscopy by placing
Cone biopsy:
the specimen on a glass slide and mixing with a salt
A procedure in which a cone of cervical tissue
solution.
comprising both the ectocervix and endocervix is
excised with either a scalpel (cold-knife conization) or a
laser loop (LEEP)
37. Colposcopy
Colposcope: a type of microscope used to acquire a Endocervical curettage (ECC)
magnified view of the ectocervix or vaginal wall - The mucous membrane of the endocervical canal is
scraped by a curette.
-Allows for assessment of the ectocervix under *Indications: Nonpregnant patients in whom
magnification. colposcopy is inconclusive
-Application of acetic acid or iodine facilitates the *Positive screening test (primary HPV test, Pap smear,
colposcopic detection of precancerous and cancerous co-testing) without visible lesion on the ectocervix
lesions *Suspicion of glandular abnormalities on cytology (e.g.,
adenocarcinoma)
Benign lesions:
- Cervical ectopy
40. Biopsic Curettage
- Nabothian cysts
The scraping or removal of tissue lining the uterine
- Cervical polyps
cavity (endometrium) with a surgical instrument called
a curette and examined under a microscope
Abnormal findings:
Indications:
- Condylomata acuminate
- Abnormal uterine bleeding
- Cervical leukoplakia
- Endometrial cancer
- Cervical intraepithelial neoplasia
- Endometrial hyperplasia
- Cervical cancer
- Uterine polyps
41. Hysterometry 43. Tubal Patency Test
Is the use of the hysterometer to measure the length of Hysterosalpingography:
the uterine cavity and the cervical canal in centimeters. - Easily done
- Good sensitivity and specificity
Normal uterine cavity length: - Can be uncomfortable
- 7 cm in nulliparas - May have false positive results (suggesting
- 8 cm in multiparas Procedure: tubal blockage due to spasm)
Laparoscopy and dye test:
1. Lithotomy position - Day-case procedure that can be combined with
2. Bimanual examination to orientate the position of hysteroscopy to assess the uterine cavity if
the uterus necessary.
3. Insert speculum - “Gold standard”
4. Desinfection of the area - Pelvic pathology (endometriosis, peritubular
adhesions) can be diagnosed and treated.
5. Grasp (catch) the superior/ anterior part of the cervix - Requires general anesthetics.
6. Introduce the hysterometer through the vagina and - Carries surgical risks.
then into the cervical and then to uterine cavity.
Hysterosalpingo-sonograph (HyCoSy):
Indication: - Ultrasound with galactose-containing contrast
- Use it before doing D&C to know how deep to medium.
introduce the curette to avoid the uterine perforation. - Similar sensitivity to HSG.
- In case of uterine tumour like leiomyoma and if the - No radiation exposure.
-
uterus is very big and we need to take biopsy by
44. Ultrasound in Gynaecology
curette we will use it to orientate obviously to know Transabdominal ultrasound:
how deep we need to inside. -An abdominal ultrasound is the easiest method of
Complications assessing the uterus, ovaries, and adnexal structures.
- Perfomation of uterus. Assessment of:
- Urogenital tract
Conditions:
- Assessment of fetal development
- Have to be done in follicular phase of the cycle (not in
- Pelvic organs
the luteal phase)
- No genital phase Transvaginal Ultrasound:
- No pregnancy Ovaries:
- Performed to diagnose ovarian cysts, tumors,
and follicular maturation
Uterus:
- Myometrium (e.g., to diagnose leiomyomas)
42. Hysterosalpingography:
- Endometrium (Endometrial thickness varies
Imaging technique involving the injection of contrast
with the menstrual cycle)
dye into the cervical canal and serial radiographs to
evaluate the uterine cavity and morphology/patency of *Postmenopausal women with an endometrial thickness
the fallopian tubes. >10 mm should undergo hysteroscopy and endometrial
- Also known as uterosalpingography. curettage to rule out endometrial carcinoma.
- HSG may also have therapeutic benefits for infertility
-Assessment of fetal development during the first
treatment. trimester
-Measurement of cervical length in cases of cervical
incompetence
Breast Ultrasound:
-Can be used to assess breast lesions which were
detected by palpation, mammography, and/or breast
MRI scans.
- Ultrasound can also be used to assess the axilla for
lymph node involvement if there is suspicion for breast
cancer.
45. Hormonal Investigations 47. Infertility- Investigations & Basic Therapeutic
- Progesterone Approaches
- Estrogens - Infertility is generally defined as the inability to
- Human placental lactogen achieve pregnancy despite regular unprotected sex after
-FSH at least one year in women <35 years of age and after 6
- LH months in women >35 years of age.
- Prolactin - Female infertility may manifest with symptoms of
- TSH T3, T4 anovulation (e.g., amenorrhea, irregular menses).
- Human chorionic gonadotropin (hCG) Diagnostics:
- ACTH - Medical history of both partners, especially
- Cortisol gynecological history (e.g., children, family history)
- Oxytocin - Assess ovulatory function
- Testosterone - Menstrual history
- Body temperature analysis to monitor menstrual
- Aldosterone
cycle
- Hormone tests (Progesterone, LH, FSH,
46. STD- Diagnosis and Prevention Estradiol, Anti-Mullerian H., TSH, Prolactin)
The most common symptoms of STIs are pain in the - Ovarian sonography: antral follicle count
suprapubic and genital area, urethral or vaginal - Endometrial Biopsy: to determine thickness
discharge, and genital lesions, which may or may not be - Imaging: assess the patency of fallopian tubes and
painful. uterus.
- Examine cervix
Diagnosis:
- Physical examination
- Chlamydia: Vulvovaginal or endocervical swab for - Pap smear
nucleic acid amplification test (NAAT) - Testing for antisperm antibodies in cervical
- Herpes Simplex: Appearance of typical rash & PCR & mucus
Culture
- Gonorrhoea: Endocervical or vulvovaginal swab with Treatment:
NAAT & Culture for sensitivity - Lifestyle modifications: cessation of alcohol, nicotine,
- Syphilis: Specific EIA for screening (IgG +IgG) and recreational drug use as they contribute to
- Trichomonas: Direct observation by wet smear & subfertility.
culture media & NAAT
- HPV: Clinical appearance & Smear tests & - Treatment of underlying causes (e.g., levothyroxine
Colposcopy for hypothyroidism, bromocriptine for
- Bacterial Vaginosis: Homogenous grey white hyperprolactinemia, metformin for PCOS)
discharge & ph>5.5 & fishy smell & “clue cells” on
microscopy Ovulation induction:
- Clomiphene citrate
Prevention: - GnRH (pulsatile): stimulation of FSH and LH
Preexposure prophylaxis: release leads to follicle maturation
1. Safe sex practice - Gonadotropins (e.g., recombinant hCG,
- Abstinence recombinant LH)
- Condom use during vaginal sex or anal sex - Tamoxifen (selective estrogen receptor
- Dental dam use during oral sex modulator)
- Mutual monogamy - GnRH-antagonists
- Reducing number of sex partners
Assisted reproductive technology:
2. Vaccination
- In vitro fertilization
- HPV, HBV, and HAV vaccine
Intrauterine insemination (IUI): a procedure in which
3. Disease-specific prophylaxis
washed and concentrated sperm are introduced directly
- Adherence to screening guidelines for STIs
into the uterine cavity
- Postexposure prophylaxis
- Oocyte donation
- HIV postexposure prophylaxis
- Surgery: removal of tubal, cervical, or uterine
- Hepatitis B postexposure prophylaxis
adhesions, myomas, and/or scar tissue
- Antibiotic postexposure prophylaxis (e.g.,
doxycycline for chlamydia or syphilis)
- Self-sampling/-testing and pooled sampling
- Expedited partner therapy
48. Family planning- practical medical strategies Preconception Counceling:
Family planning is the ability of individuals and couples A form of medical counselling provided to couples of
to control their number of children and the spacing reproductive age who are planning to conceive.
between births.
Goals:
Goals: - Identify and address any modifiable factors that may
Improve pregnancy planning and spacing negatively affect pregnancy and childbirth
Prevent unintended pregnancies - Educate couples about risks and how to mitigate
them.
STI prevention
Key components:
Family planning services include:
- Risk assessment (e.g., immunizations, medication
- Fertility counselling use, genetic carrier screening, environmental risks)
- Reproductive life plan and preconception - Healthy lifestyle promotion (e.g., counseling on
counselling proper nutrition, regular exercise, smoking cessation,
- Pregnancy testing and counselling alcohol use)
- STI counselling - Medical and psychosocial intervention and
- Preventive health counselling (e.g., breast counseling (e.g., chronic disease management, folic
cancer screening, cervical cancer screening) acid supplementation, psychosocial risks)
- Physical assessment
Family planning counseling:
Counseling on the use of contraceptives and infertility Emergency Contraception:
treatment to prevent pregnancy or attain the desired Refers to measures taken to prevent pregnancy within 5
number of children and determine the spacing of days of unprotected intercourse or contraception failure
pregnancies. (e.g., condom breakage, missed oral contraceptives).
Method of TOP depends on gestation of pregnancy and the woman‘s choice. Procedures offered also vary
from one centre to another (usually determined by local resources).
Surgical
<7wks: conventional suction termination should be avoided.
7–13wks: conventional suction termination is appropriate, although, in some settings, the skill and
experience of the practitioner may make medical TOP more appropriate at gestations >12wks.
>13wks: dilatation and evacuation following cervical preparation; requires skilled practitioners (with
necessary instruments and sufficiently large case load to maintain skills). The greater gestation, the
higher the risk of bleeding, incomplete evacuation, and perforation.
Cervical preparation is highly beneficial:
it reduces difficulties with cervical dilation
particularly if patient is <18yrs or gestation is >10wks.
Possible regimes include:
misoprostol 400 micrograms PV 3h prior to surgery, or
gemeprost 1mg PV 3h prior to surgery, or
mifepristone 600mg PO 36–48h prior to surgery.
Medical
<9 wks: using mifepristone priming plus a prostaglandin regime (misoprostol) is the most effective
method of TOP in gestations <9wks. Antiprogesterone (given 24–48h prior), which results in uterine
contractions, bleeding from the placental bed, and sensitization of uterus to prostaglandins. Its use has
been shown to reduce the treatment to delivery interval in medical TOP.
9–13wks: medical TOP is an appropriate, safe, and effective alternative to surgery (incomplete
procedure rates increase after 9wks).
13–24 wks: medical TOP as above is also appropriate, safe, and effective in this group. Feticide
should be considered in advanced gestations (>20wks).