R

Path to success KOTA (RAJASTHAN)

ROADMAP - A SOLUTION

A CH3 – CH2 – COOH

B CH3 – CH – COOH HVZ reaction
Br
C CH3 – CH – COOH Alanine
NH 2
D CH3 – CH2 – NH2 Schmidt degradation
E Ph – SO2 – NH – Et
F CH3 – CH2 – OH Diazotisation
G CH3 – CH2 – COOEt Esterification
O
H CH3 – CH2 – C – CH – COOEt Claisen condensation
CH3
O
I CH3 – CH 2 – C – CH2 – CH 3
O
J CH3 – CH 2 – C – Cl
K CH3 – CH2 – CH2 – COOH Arndt Eistert reaction
L CH3 – CH2 – Br Hundsdeicker reaction
M CH3 – CH = O
N CH3 – CH – CN Cyanohydrin formation
OH
OH
O CH3 – CH – COOH Lactic acid
O
P CH3 – C – COOH Pyruvic acid
Q1, Q2 and Q3 is a mixture of three lactides.
Here it is heating effect of a-hydroxy acid is applied.
Me Me Me H
CO – O CO – O

O – CO O – CO
H H (±) H Me

Q1 / Q2 Q3 meso
optically active due to COS
 R

Path to success KOTA (RAJASTHAN)

R CHI3
COOH
S oxalic acid
COOH
Formation of R and S is Iodoform reaction
T HCOOH (Heating effect on oxalic acid)
U HC º CH
V H2C = CH – COOH Acrylic acid
W H2C = CH – COOMe methyl acrylate
This on polymerisation gives polymethyl acrylate (PMA) substance used to make acrylic glasses.
O
X CH3 – CH2 – C – NH – CH2 – CH3 Schmidt reaction
Y CH3 – CH2 – NC Carbylamine reaction
Z CH3 – CH2 – CH2 – CH3 Kolbe’s electrolysis.