• Infectious, inflammatory systemic disease caused by
exposure to mycobacterium tuberculosis that infects lungs, lymph nodes and other organs. Etiology & Pathophysiology: • Close contact or prolonged exposure with TB patients is risk factor. • Immunocompromised patients have increased risk of TB. • Mode of transmission: inhalation of mycobacterium tuberculosis bacillus into lungs. • TB infection may lead to necrotic lung tissues or may develop cavities. • The infection can also spread to other organs, including brain & spinal cord. Clinical Presentation: • Common signs are - ➢ Productive cough ➢ Weight loss ➢ Fever ➢ Fatigue ➢ Anorexia • Complications include - ➢ Bronchopleural fistula ➢ Pleural effusion ➢ Sudden lung collapse ➢ Spread of infection to brain and spinal cord ❖Many people are unaware of been infected (Latent TB), in them only sign of infection may be a Positive skin test. Medical Interventions: • Prevention of TB ➢ Limiting contact with infected individuals ➢ Reducing airborne exposure by covering mouth & nose while coughing ➢ Addressing risk factors • TB pharmacotherapy is curative but must be taken over a long period of time (6-12 months) PT Management: • Improve poor gas exchange • ACTs • Secretion removal • Cough assist techniques in weak patients • Hospitalized active TB patients must be placed in negative pressure room to limit airborne spreading • PT must take preventive measures to avoid TB infection