Week 1 TBL

PUBH-151
Fall-2020

1. A patient with hypertension came to a primary health care center (PHCC). Which of
the following physician actions is NOT in keeping with the process of EBM?
A- Ask focused questions about the disease
B- Acquire best available evidence
C- Critically appraise the evidence
D- Consider patient values
E- Prescribe the most commonly used medication

2. A clinician sees a patient on multiple medications and has a few questions he would
like to answer about the effect of the medications on different patient outcomes. How
should a clinician approach these questions?
A. Construct a series of PICOs, and examine them all together
B. Expand the PICO to contain all of the relevant medications and outcomes
C. Expand the PICO to contain some, but not all of the extra medications and outcomes
D. Select a PICO question with a single medication and outcome of interest
E. Expand the PICO to contain all medications but limit to one outcome

3. Dr. Hadi is an accomplished neurologist at Hamad Medical Corporation. One of his

patients, Mohammad is a 21-year-old university student with epilepsy. Mohammad
requested Dr. Hadi to change his current medication (carbamazepine) because it makes
him drowsy and he would prefer a change in medication without this side effect. Dr. Hadi
changed his medication to lamotrigine after considering his current clinical condition and
his request. The best decision-making process by the doctor would be based on:
A. His previous experience
B. A similar case that he had last year
C. His recent review of the scientific literature
D. The briefing he received from the medical representative of lamotrigine
E. Conducting a small experiment on Mohammad before prescribing lamotrigine

4. Dr Luis was giving a lecture on Evidence Based Medicine (EBM) to clinicians. Which
of the following statements best describes what Dr Luis would ask doctors to avoid?
A- Keep up-to-date with the evidence in the literature
B- Ensure that decisions are based on the best available evidence
C- Critically appraise evidence for its validity
D- Use textbooks regularly to make clinical decisions
E- Revise key concepts in epidemiology and biostatistics

5. A patient with migraine went to Hamad General Hospital because her current
medication was causing her weakness, fatigue, difficulty in concentrating and loss of
appetite. The doctor decides to prescribe a new medication. Which of the following
sources will provide the doctor with the highest level of evidence?
A- Randomized controlled trials (RCTs)
B- Case reports
C- Observational studies (e.g. cohort, case-control)
D- Systematic reviews and meta-analyses of RCTs
E- Expert opinion

6. In children with the common cold, is oral zinc compared to placebo effective in
reducing the duration of symptoms?
What type of question is this?
A. Background question
B. Foreground question
C. Descriptive question
D. Analytical question
E. Experimental question
7. Can gloves prevent transmission of infectious diseases?
What type of question is this?
A. Background question
B. Foreground question
C. PICO question
D. Descriptive question
E. Analytical question

8. In children with the common cold, is oral zinc compared to placebo effective in
reducing the duration of symptoms?
According to the PICO framework identify the P (Population) in this question?
A. Oral zinc
B. Children with common cold
C. Placebo
D. Reduced symptoms
E. Children

9. In patients with acute myocardial infarction (MI) admitted to tertiary care, does daily
low dose of oral aspirin lead to higher survival rates as compared to placebo?
According to the PICO framework identify the O (Outcome) in this question?
A. Patients with MI
B. Low dose of aspirin
C. High dose of aspirin
D. Placebo
E. Survival rates