| | | CS (Main) Exam,2019 ferater DETACHABLE fateen-fara (aga-75 1) MEDICAL SCIENCE (Paper I) Fretiter eer : cet ee ITA ates : 250 Time Allowed : Three Hours Maximum Marks : 250 WeA-a eae fade eazet Br weit & sax BA a as Penk ween arate a carl VF | wath ary wet Gt St vat Hava E are fest atte aidtah ata F wT E uttered at ger ate weit & ae 23 € 1 wer domi atk 5 aftard € aan art FB wets ae aa-|-a UH eT Ga Pe ate weit Sa Sf wees wet / ar & ses Ga TAA Ae mE E 1 Swett oe Veh arene HFS on safe rear Teta aT wor F Pear are, ste ge ATE wae ate weae-am (agatz,) gfe & ya-ge aif ffs eat x feet oT arf, | afterftrer rear 3 aaferheen aver fevett aren H fore amy sae ae aE sien wet AeA | weit aq din, wet Ree &, ar age fer aT aAfeT | ret agli araeeres erat, ara Peer a Rane ger a Set A are Ar | ge By Site Afertt ar weit Par ST waa eI weit & aeet At corer gergere A oreaht | ale aver et A, at wer H sae A oT A ret Tae ae Sat sree: ear mar St | e-wE-Tae Gera Harel BIST GMT YE AT TAS sir FH VIS ET @ wer arn afer | QUESTION PAPER SPECIFIC INSTRUCTIONS Please read each of the following instructions carefully before attempting questions. ‘There are EIGHT questions divided in TWO SECTIONS and printed both in HINDI and in ENGLISH. Candidate has to attempt FIVE questions in all. Question Nos. 1 and 5 are compulsory and out of the remaining, any THREE are to be attempted choosing at least ONE question from each Section. The number of marks carried by a question/part is indicated against it. Answers must be written in the medium authorized in the Admission Certificate which must be stated clearly on the cover of this Question-cum-Answer (QCA) Booklet in the space provided. No marks will be given for answers written in a medium other than the authorized one. Word limit in questions, wherever specified, should be adhered to. Ilustrate your answers with suitable sketches and diagrams, wherever considered necessary. Coloured pencils may be used for the purpose. ‘Attempts of questions shall be counted in sequential order. Unless struck off, attempt of a question shall be counted even if attempted partly. Any page or portion of the page left blank in the Question-cum-Answer Booklet must be clearly struck off. 1 ‘SDFsWsMDCS1L@) 1.0) 140) 1.44)(i) 1.dXii) TS ‘a’ SECTION ‘A’ mradt arta after & fears west, ate, anf, freon we wat Fife | Discuss the Functional Components, Nucleus, Course, Distribution of Seventh Cranial Nerve. 10 Ue 52 a8 ong & faranftres ererelt cafes ot arigaa wan fret A wah & are wat wféarg @ | xa aafte & aft (tex) aarcaa t ger anf aan aqafersn Bry wat & faga & wat Hf | ‘A 52 year old chronic alcoholic man has difficulty in his gait with imbalance and tendency to fall. Elaborate the underlying physiology of motor coordination and features of cerebellar dysfunction. 10 We 35 Bet ST TEN ATT BT 8 Se, YE A eT Ue Stat & daar At fRreraal | are ara | feat dae ee (Ber art alen) feet war sik fend za wa 2: ‘gat (Gea) facie 10 fates /3.xft-att. (0-1-1-2 fife /2.aat.) wera (sree) faettefer : 9 fifa /2 tat. (< 0.3 fife /3.zft.aft.) Tenfrs giaseréta (wut) : 31 984, /at. (<35 916.4, /cA.) wane gins (vue) : 33 ag. /ah. (< 40 918.4. /at.) anda (wena) Glenda (uur): 800 aka. /at. (45-150 918.4, /aA.) @) wants fret ar @ ate wi? Gi) AG Fa % waa Freeh er eh 7 ‘A 35 year old man presented with complaints of generalised weakness, loss of appetite and yellowish discolouration of eyes. The liver function test was done and the report is as follows : Total bilirubin : 10 mg/dL (0-1-1-2 mg/dL) Direct bilirubin : 9 mg/dL (< 0-3 mg/dL) Alanine transaminase (ALT): — 31 IU/L (< 35 IU/L) Aspartate transaminase (AST) : 33 IU/L (< 40 IU/L) Alkaline phosphatase (ALP): 800 IU/L (45-150 IU/L) (What is the most likely diagnosis and why ? (ii) What will be the expected findings in urine and stool ? 54+5=10 wa & eR Sta Ht Gag Sifira | Enumerate palmar spaces of Hand. 5 ae a ae & ferns saad et atag Aire | Enumerate the Developmental Components of thoraco Abdominal Diaphragm. 5 ‘SDF-U4MDCS 21) 2a) 2.(0)() 2.(b)Gi) reg & aetoetad wer ar aia ak ce ait wea Hert | aR FH fee fad | Describe Bronchopulmonary segment of lungs. Add a note on the importance of organ transplantation. 10 Preaferfan atteat & arenfs ger & sisi ar aia fa; 1, derrs ate otk Wa 2. Sy 3. wae 4. fe amg atte fran argh 5. Wat Describe the knee joint under the following headings : Types, Articular surface Ligaments Relations . Blood supply and nerve supply Movements 20 vitae aA (Heqge wees) B enfer VA ae atea:-arat (eA) a sa org SrA aTefh aAfrarait % wart & aqan wa ag HI a fers | Enumerate various hormones secreted by pituitary gland with their cell types. 5 Ter 28a & afer a HOY ra site Bat At eRe H ahh ate SA aT sre Sie FTA ara Gt ee ar Eee (MrT) a SeEqaT (stafeon) A sett es 1 ae afte fie stant & afta @ a sees ae ere ? ga ae & Gdanfers (wetlae) vgs aft & arat (Gteqedt eritat) & Bearers eax ar Pract ak car geht Teer A uber & ait H st fe | ‘A.28 year old man noticed marked enlargement of bones of his hands and feet along with coarsening of facial features and prognathism. He was diagnosed as a case of pituitary adenoma. What ailment he is suffering from and its features ? Describe physiological status of anterior pituitary hormones of this patient and its control mechanism. 10 yrere 3 ‘SDF-U“MDCS2H) 2.0) 3.(a)(i) 3.(ay(ii) 3.(b) 3.0) writs (aa ofa) viftte aa vf Chaar.) & fear cer sat aitifirs weit At aaa at cer fatter Hf water i art & faq data. & ats vie sath ar seta Athy | Discuss the principle and the steps involved in real time PCR. Enlist any five applications of PCR in medicine. 5+5=10 Safar ar ta-erafre wire A aed are | Explain the significance of selenium in biochemical processes. 5 Gin, Aat (Te) we age & frac ce sqeen & waif adites easit a aol at ara @t ga when H ents fair acarrers aeaaTe wa Sas APE (aaa) At at wat fifi | Describe the physiological mechanism involved in control and maintenance of tone, posture and equilibrium and its various anatomical structures and pathways. 10 tie & fafa wert saersit ar sah $8.ch, ois oforat & ara fea & aie at | eRe a Ree wea & are aig & aril At fetaar ae cer ara-arer Waka H aanfia afar A sh zat Ac | Elaborate types and stages of sleep along with EEG findings. Describe neuronal and neurohumoral mechanism causing sleep with possible role of serotonin in it. 10 ‘Sif ste wee aafeatt & sracenftes (eniiaa) Praca ar fer & avi ae | eetsherton & avi sft Aahrs afreafirat a st feet Fire 1 Discuss in detail the hormonal regulation of calcium and phosphate homeostasis. Add a note on the causes and clinical manifestations of hypocalcemia. 10+5=15 frafifaa sitet & sivia amma ar aia Fife | 1, srafeafar 2. ee aaa 3. *Raftaa ws sia (free) a diet 4, BRR angfs Ua weet vet Prat 5. Fert aoe car fae Describe stomach under the following headings : . Position . Gross features . Peritoneal and visceral relation . Blood supply and lymphatic drainage . Clinical anatomy 15 Vewene SDF-U-MDCS 44.ayi) 4a)(ii) 4.00)(i) 4.(b)(ii) 44c)(i) 4.(0\Gi) 4.(c)(iii) 5a) 5.(b)(i) 5.(b)(ii) ark % fafa 3! & arate sik Sa-cerafie after ar Pega 8 ait at Prarie 3) ft ant ft aftoatinat afc sam gfe & fore sreifires wahrerra (Fa) Sisto ft Rew Ae | Explain in detail the absorption and biochemical role of vitamin K in the body. Add a note on the deficiency manifestations of vitamin K along with relevant laboratory investigations for confirmation. 10 ‘freer at oferta at | gees tect A are Ud eae cat a lag Afi | Define clearance. Explain its significance and enumerate the methods available for its determination. 10 aprger sae A afr omen aRhrger gift wi wee sige ersdieen & ara Fifi | Illustrate a diagram of Neuromuscular function elaborating neuromuscular transmission and muscular contraction. 3 ara & ker et are eer Te Tpaaiearsit @ wale fata oRatat ar avis Atha | Describe various Cardiovascular changes during physical exercises. 10 saga (arr we) A eae woke cat, ex angle afk erates Het aT avi ffir | Describe the gross anatomy, blood supply and applied importance of Thyroid gland. 8 afer & aig ver (are Hex) & fairs weer & refers dgeil at eas Ffire | Enumerate the different types of myelineted fibers in the cerebral white matter. 4 fra weir & ferns saaal ar rag ea a as Afr | Enumerate the Developmental Components of Inferior vena cava. 3 GUS ‘B’ SECTION ‘B’ Wer & Sifter 8 sera wemers en E 7 safer Garr Ht eet ae ar aia Afra | What are the major cell derived mediators of Inflammation ? Describe their role in acute Inflammation. 10 aft Afriataes Areonsfea & watraen fre ar ait Aare | Discuss the laboratory diagnosis of acute meningococcal meningitis. 5 aa am af 4 cad al. & aa ar van Pert Ft are Fifi | Discuss the laboratory diagnosis of HIV in an asymptomatic individual. 5 5 ‘SDF-U-MDCS5.40) 5.4) 5.) 6a) 6.(ay(ii) 6.(c)(i) 6.(c)ii) 74a) aeaathiee carat & sett 8 MA ara ars Pare wera A sal Sie | Discuss general toxicity associated with the use of cytotoxic drugs. 10 orat & yasiag wa otter et arf gfe areal a ala Ary | What are the growth factors involved in Regeneration and repair of tissues? 10 ade vetere ay Ft aren at | fafa we A aac VARI Hy a aia Fife | Explain violent asphyxial death. Write about various types of violent asphyxial death. 545=10 Ure araciae Sehr (GcH.Ua.) /(GR.AR.Y) FM oie we & wae tat & ak 4 avis Sift 1 Give the laboratory findings in a case of Acute Myeloid leukemia et fusion gene type. hen sary dah afer at were (waye aftetan shfeedt argaréfea) at ar wrt (caesar ), eae Ua gen caffe fir & ait H fetta | Give the etiopathogenesis, Gross and microscopic picture of Acute bacterial osteomyelitis. 10 wate (sriferdta torgea) & saan 4 fier fort fafa sat At afer errerstire waa St watt Fare sre @ 7 aeathia afar Ft fier fate, quent sik Aafia Seah a sat Afar | ‘What are different classes of oral hypoglycaemic drugs used in the management of diabetes mellitus ? Discuss the mechanism of action, side effects and clinical uses of sulphonyl urea. 15 eet seen ar oreafeen Gr ara, Ser eT a wareTeT Fert at ais Sie | Discuss epidemiology, pathogenesis and laboratory diagnosis of Polio virus infection. 75 Star Sala & cae at lag Se | seers Seer dae a wale F atas At fafir an ait ify | Enumerate infections caused by candida species. Suggest a laboratory approach for the diagnosis of invasive candidial infections. 75 S.aa.u. sige ors (flan fife) ser 8? geht wie & fare shifter afte @ fats aR a wa a araenfrat Set safe 2 Saaz. fra ware? What is DNA finger printing ? What precautions should be taken while collecting various samples from living human being for this test ? What is DNA Bill ? 5+10+5=20 ‘SDF-U-MDCS 67.40) 1.40) T4c\(i) TAcM(ii) Toi) 84a)(i) 8.(a)(ii) 8.00) 8.0) 8.(0)(i) 8.(c)(ii) ware et At after A sare Afar | Fafeicer—fares arr Hare eer A sraeeTsHt At am Fem @ 7 Discuss the process of wound healing. What is the significance of stages of wound healing in Medico-legal cases ? S+10=15 aren fifie fs at : Explain why : wis tant froa ge quai i of E1 Fungal infections have been on the rise over the past few decades. 5 ara wifes aq aA B vera Tea TENA ag TAT eI Sudden withdrawal of Clonidine causes rebound hypertension. 5 wafer & gama & faq ardifer-gittigia & afBer a aarqe sor arr Bar arte Artemether-Lumefantrine combination for treatment of malaria should be administered with fatty food. 5 oa wea at eT Set Wa eee Fer ar eats avs AAC | Briefly describe the pathogenesis and laboratory diagnosis of enteric fever. 10 verseiftan argaae & stat am ar aay A aia ak | wether a ware Piet Be ae? Describe in brief the life-cycle of Plasmodium vivax. How will you make a laboratory diagnosis of malaria ? 10 da iam ania witePmea B to, wafer wd epee ft fran Fifi | Give the pathogenesis, Urinary findings and Immunoflorescence picture in Acute Post infection glomerulonephritis. 20 Frafefan & arf at ft ufear, gare sfc sftueia seinit Ah freee Afr: Discuss precisely the mechanism of action, side effects and medical uses of the following : 5x2=10 wetgittia Allopurinol eaiterds Telmisartan a SDF-U-MDCS