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Case 5 Licensing A New Drug
Case 5 Licensing A New Drug
Analysis
Case 5:
Licensing a New Drug
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1. Case Description
Theory
The key elements for representing events related to a decision in a
decision tree are:
• Decision node (actions to take)
• Random node (event with probability)
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Case 5: Licensing a New Drug
2. Case Analysis
1. Complete the following decision tree. You may use the fillable version
available in the file Case 5 Decision Trees.docx. Fill in the blue boxes with
probabilities, the costs (red) in millions of USD next to the -$ symbols and
the incomes (green) in millions of USD next to the +$ symbols, where
D=Depression and P=Weight loss (for instance D P2 means Phase II would
show that Davanrik would be effective for weight loss but not depression).
Note that in Case 5 Related Document Merck&Company.pdf, the present
value (PV) can be equated to income.
-$ D P3 +$
D P3
D P2
-$ D P3 +$
-$
D P2 2 D P3
Phase I Success -$ DP 3 +$
-$
D P3 +$
-$ -$
DP 2 -$
D P3+$
-$ -$
License
D P3
D P2
Phase I Failure
Do Not
License
-$
2. Should Merck license the drug? What is the expected profit? To answer
this, move the information of each branch of the decision tree to the rows of
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Case 5: Licensing a New Drug
the following table. Indicate the probabilities and costs of each phase, and
the corresponding income (see the first row as an example), and calculate
the total probability and profit of each branch. Use these to finally calculate
the expected profit.
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