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    The document analyzes the agreement between values of blood glucose obtained from capillary blood glucose meters (CBGm) and interstitial glucose sensors (IGs) using data from 708 individuals. A correlation was found between the two methods, however a Bland-Altman analysis showed inconsistencies, with IGs reporting values up to 41 units below or 74 units above those from CBGm, particularly in the hyperglycemic range. The conclusions state it is important for physicians to advise patients using IGs to also use CBGm to prevent negative clinical outcomes from inconsistencies.

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    The document analyzes the agreement between values of blood glucose obtained from capillary blood glucose meters (CBGm) and interstitial glucose sensors (IGs) using data from 708 individuals. A correlation was found between the two methods, however a Bland-Altman analysis showed inconsistencies, with IGs reporting values up to 41 units below or 74 units above those from CBGm, particularly in the hyperglycemic range. The conclusions state it is important for physicians to advise patients using IGs to also use CBGm to prevent negative clinical outcomes from inconsistencies.

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    © All Rights Reserved
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    15 views1 page

    AATD

    Uploaded by

    camilafcaldato
    The document analyzes the agreement between values of blood glucose obtained from capillary blood glucose meters (CBGm) and interstitial glucose sensors (IGs) using data from 708 individuals. A correlation was found between the two methods, however a Bland-Altman analysis showed inconsistencies, with IGs reporting values up to 41 units below or 74 units above those from CBGm, particularly in the hyperglycemic range. The conclusions state it is important for physicians to advise patients using IGs to also use CBGm to prevent negative clinical outcomes from inconsistencies.

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    of 1

    ATTENTION TO PREVENTION: ESTIMATIVE OF AGREEMENT BETWEEN

    CAPILLARY BLOOD GLUCOSE METERS AND INTERSTITIAL GLUCOSE SENSORS


    Camila Fernandes Caldato, Neylane Araújo Cordeiro de Santana, Cláudio Eduardo Corrêa Teixeira
    Pará State University Center, Medicine, Brazil
    AS04. Glucose sensors

    BACKGROUNDS AND AIMS RESULTS


    Interstitial glucose sensors (IGs) are considered accurate to estimate glycemic Values of glucose obtained with IGs were well-correlated with values of glucose
    status, “eliminating” the need for routine fingerstick to measure glycemia. The obtained with CBGm (r = 0.869; R2 = 0.755). However, in the analysis of
    rationale for this lies in the fact that linear correlation of measurements agreement between values of glucose obtained with IGs and CBGm, the former
    performed with traditional capillary blood glucose meters (CBGm) and IGs are showed values up to ~41 units below or ~74 units above that given by the latter,
    assumed as evidence of high agreement between these methods. However, being this disagreement higher in the range of hyperglycemia (> 100 mg/dL)
    there is a critical difference between “correlation” and “agreement”: while than in the range of hypoglycemia (< 70 mg/dL).
    “correlation” refers to a quantitative relationship between two variables,
    “agreement” refers to the concordance between measurements of a unique
    variable performed by different methods. Thus, given the relevance of this
    issue, we analyzed both “correlation” and “agreement” between CBGm and IGs.

    METHODS
    Using data from the literature of both capillary blood glucose meters (CBGm)
    and interstitial glucose sensors (IGs) obtained of the same individuals (n = 708),
    we calculated coefficients of linear correlation and determination and performed
    Bland-Altman agreement analysis.

    CONCLUSIONS
    It is important to discuss how physicians should advise users of IGs about also
    performing measurements of glycemia using CBGm, mainly to prevent negative
    clinical outcomes due to inconsistencies along diabetes follow-up.

    REFERENCES
    1. Garber AJ, Handelsman Y, Grunberger G, Einhorn D, Abrahamson MJ,
    Barzilay JI, et al. (2020). Consensus Statement by the American Association of
    Clinical Endocrinologists and American College of Endocrinology on the
    Comprehensive Type 2 Diabetes Management Algorithm - 2020 Executive
    Summary. End Pract, 26(1): 107-39.
    2. Heinemann L. (2018). Continuous Glucose Monitoring (CGM) or Blood
    Glucose Monitoring (BGM): Interactions and Implications. J Diabetes Sci
    Technol, 12(4): 873-79. /
    3. Bailey T, Bode BW, BW. Christiansen MP, Christiansen MP, Klaff LJ, Alva S.
    (2015). The Performance and Usability of a Factory-Calibrated Flash Glucose
    Monitoring System. Diab Tech & Therap, 17(11): 787-94.
    4. Giavarina D. (2015). Understanding Bland Altman analysis. Biochem Med
    (Zagreb), 25(2): 141-51.

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