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PRESCRIPTION -
 THE FIRST STEP TO DISPENCE LEGAL PRESCRIPTION.
 VALIDITY –
 Indicates the right medication to the right patient on the right time.
 Check the validity date of prescription (Normal & Special prescription)
 Normal prescription validity date = 30 days
 Special prescription validity date = 15 days
 Check the color of prescription - Narcotic – Pink
-PSYCOTROPIC – Blue
 LEGALITY –
 Indicates full information about health Institution & prescribers.
 Name & address of health Institutions
 Serial no
 Prescriber name
 Qualification & seal of health Institution.
 COMPLETENESS –
 Indicates full information about patient, name, address, age & sex.
 CLINICAL INDICATION –
 Parameter you can evaluate Diagnostic (DX) Indication (RX).

 Dose calculation - food drug interaction


 Drug interaction - contraindication
 LABELING –
 Should be local language & the client understand with detail explanation.
 Name of medication - dosage form
 Strength - frequency
 COUNCELING –
 Consists of useful information with regard to drug administration.
 Drug storage - related advice
 Drug Drug Interaction
 DISPENSING –
 Delivering of medicine to the right patient.
 By checking medication card & patient Id
 REGISTERATION –
 Register the dispensed drug & quantities on registration book.
 Help to audit product transaction & quantify the drug.
 DOCUMENTATION –
 File the prescription
 Normal prescription securely for 2 years

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 Special prescription securely for 5 years
 PART 1.
 ABBREVATION
 D5W – DEXTROSE 5% SOLUTION
 D5NS – DEXTROSE 5% IN NORMAL SALINE (0.9%)
 DAW – DISPENCE AS WRITTEN
 DIED – EVERY OTHE DAY
 SC,SUBC – SUBCUTANEOUS (UNDER THE SKIN)
 SL – SUBLINGUALLY (UNDER THE TONGUE)
 STAT – IMMIDIATELY,AT ONCE
 SUPP – SUPPOSITORY
 TBSP – TABLE SPOON
 TSP – TEA SPOON
 TROCHA – LOZENGA
 TID – THREE TIMES A DAY
 TDS – THREE TIMES A DAY
 TIW – THREE TIMES A WEEK
 TOP – TOPICAL
 UD,UT,DICT – AS DIRECTED
 UNG – OINTEMENT
 VAG – VAGINALLY
 W – WITH
 W/O – WITH OUT
 X – TIMAS
 M – MIX
 MIST – MIX
 MITTE – SEND
 AA – OF EACH,
 AD - UP TO
 AC – BEFORE MEAL
 AD – RIGHT EAR
 AL,AS – LEAFT EAR
 AGIT – SHAKE
 AM – MORNING,BEFORE NOON
 AU – BOTH EAR
 BIS – TWICE
 BID – TWICE DAILY
 BM – BOWEL MOVEMENT
 BS – BLOOD SUGAR
 BSA – BODY SURFACE AREA
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 C – FOOD
 Cc,Cf – WITH FOOD
 CR,CRM – CREAM
 YO – YEARS OLD
 QH – EVERY HOUR
 QHS – EVERY NIGHT AT BED TIME
 QD – EVERY DAY
 QID – FOUR TIMES A DAY
 QOD,QAD – EVERY OTHER DAY
 QGH – EVERY FOUR HOURS
 R – RECTAL
 QS – A SUFFICIENT QUANTITIY
 REP,REPT – REPEATS
 RL,R/L – RINGERS LACTATE
 DW – DISTLLED WATER
 ELIX – ELIXER
 EMP – AS DIRECTED
 ET – AND
 EXAD – IN WATER
 GTT – DROP
 HS – AT BED TIME
 LIG – SOLUTION
 LOT – LOTION
 NEBULE – A SPRAY
 NMT – NOT MORE THAN
 NOCT – AT NIGHT
 NS – NORMAL SALINE (0.9%)
 NTE – NOT TO EXCEED
 O2,O2 – BOTH EYE
 OD – RIGHT EYE
 OS – LEFT EYE
 OU – BOTH EYE
 OZ – ONCE
 PC – AFTER MEAL
 PRN – AS NEEDED
 PO – BY MOUTH OR ORALLY
 PR – BY RECTUM
 Q – EVERY
 QOD.QAD – EVERY OTHER DAY
 QAM – EVERY DAY BEFORE NOON

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 SO,S – IF THERE IS A NEED

BIN CARD ABBREVATION –


 CT – TOTAL CONSUMPTION
 CA – AVERAGE MONTHELY CONSUMPTION
 QO – QUANTITIY ORDER
 SS – SAFETY STOCK
 SMAX – MAXIMUM STOCK
 SMIN – MINIMUM STOCK
 RM – REVIEW PERIOD IN MONTH (12MONTH)
 OS – OPENING STOCK
 RS – RECEVING STOCK
 CS – CLOSING STOCK
 LT – LEAD TIME
 PP – PEROCUREMENT PERIOD
 SI – STOCK IN INVENTORY
 SO – STOCK IN ORDER
 DOS – DAY OUT OF STOCK
 N.B = LT&PP ARE ALWAYS GIVEN
 PART 2.
 PRESCRIPTION PROCESSING & STIMULATION
1.HINDIA HOSPIATAL

 Patient name – SELAM - sex - F


 Age – 28 - card – 0014
 DX – allergy & UTI
 RX – PREDINSOLONE 30mg PO QD(every each day) for 10 days.
 PREDINSOLONE 20mg PO QD for 10 days.
 PREDINSOLONE 10mg PO QD for 10 days.
 PREDINSOLONE 5mg PO QD for 10 days.
 NORFLIXACILLIN 400mg PO QD for 7 days. (is not correct it gives for BID)
 FESO4 300mg PO HS( at bed time) for 30 days.
 COST

 PREDINSOLONE 0.35cent
 NORFLOXACILLIN 0.70cent
 FESO4 0.40cent
 SOLUTION
 PRED

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 We have 5mg PRED
 PRED 30mg = 30÷5 = 6 (6×1×10) = 60
 PRED 20mg = 20÷5 = 4 (4×1×10) = 40
 PRED 10mg = 10÷5 = 2 (2×1×10) =20
 PRED 5mg = 5÷5 = 1 (1×1×10) = 10
 Total needed PRED (60+40+20+10) = 130 Tab. (130×0.35) = 45.50
 NORF
 2×7= 14 (14×0.70) = 9.80
 FESO4
 1×30 = 30 (30×0.40) = 12

EXPLANATORY

 PREDINSOLONE – IS CORTICOSTEROID

Is stabilize blood vessel, restore sensitivity, down and release of inflammatory chemicals.

 MOA
 Block synthesis of ARACHIDONIC acid
 Reduce bronchial
 Increase responsiveness
 USE – ( allergy, asthma, conjunctivitis )
 SIDE EFFECT – decrease immunity, OSTEOPOROSIS.
 CONTRAINDICATION – HIV patient & TB PATIENT.
 PREDINSOLONE IS NOT GIVE FOR ASTHMATIC PREGNANT GIVE SULBUTAMOL.
 NORFLOXACILLIN – IS CHLOROQUINOLONES.

BACTERICIDAL BROAD SPECTRUM DRUG.

It IS 2nd GENERATION of CHLOROQUINOLONES.

 MOA
 Inhibit DNA & bacterial TOPOISOMERASE.
 USE – (UTI bacterial infection that affect parts of urinary tract)
 SIDE EFFECT – GASTERO INTESTINAL 5%(nausea, vomiting & diarrhea) &
HEPATOXICITY (liver)
 CONTRAINDICATION – all CHLOROQUINOLONES divalent & trivalent CATIONS. So
do not give for pregnant & milk.
(NOR VS FESO4 ) drug interaction so time gap 2hrs
For pregnancy safe drug CEFTRIAXONE 3rd generation
 Use – surgical prophylaxis & STAPHYLOCOCCAL infection.
 FESO4 – is supplement to PREDINSOLONE because it increase immunity.

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Is MICROCYTIC anemia (chronic blood loss, iron deficiency & THALASSEMIA)

It is oral preparation.

 USE – (treatment of iron deficiency (anemia), prophylaxis, pregnancy, lactation, infant


growing children, professional blood donor).
 SIDE EFFECT- nausea, vomiting & metallic taste.

2.HANAN HOSPITAL

 Patient Name – MRX - SEX - M


 Age – 50 - CARD – 0014

DX – THROMBOSIS, GIARDIASIS, & PHNEMONIA.

RX – WARFARIN 2mg PO QD for 30 days.

 METRONIDAZOLE 500 mg PO TID FOR 7 days. (on hands we have 250mg).


 PPF – 800,000 IV IM QD for 7 days.
 COST

 WARFARIN 1vial = 10
 METRONIDAZOLE 0.99cent
 PPF 0.88cent
 SYRINGE 5CC 1birr
 SYRINGE 10CC 2 birr
 WATER FOR INJECTION 2
 SOLUTION
 WARFARIN = 1×30 = 30 (30×0.99) = 29.70
 METRONIDAZOLE = we have on hand 250mg 2×3×7 = 42 (42×0.88) = 36.96
 PPF = 1 vial = 4,000,000 IU
 (800,000×1×7/4,000,000) = 1.4 or 2 vial
 In day we give ml of ( 1 vial = 10ml )
 (1.4 = ? )
 (1.4×10= 14) ( 14/7days ) = 2 vials
 Or 1 vial = (10ml × 800,000/ 4,000,000) = 2ml
 How many syringe needed ?
 5cc = 7(day)×1(cost) = 7
 10cc = 2×2 = 4
 1 vial = (10ml or 10cc)
 Total amount of needed syringe 7(5cc) & 2(10cc) = 9 syringe needed.

EXPLANATORY

 WARFARIN – is oral anticoagulant & antagonist of vitamin k.


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USE – prophylaxis of THROMBOSIS

SIDE EFFECT – HEMORRAGE(bleeding)

MOA – vitamin k synthesis inhibitor(antagonist).

 METRONIDAZOLE – an antibiotic, AMBICIDES, & ANTIPROTOZOAN.

drug of choice treatment of extra luminal AMOBESASIS.

Kills TROPOZOITES but not cyst ( E- HISTOLYTICA).

TINIDAZOLE – is better toxicity.

Luminal AMBECIDES – for treating intestinal infection

MOA – inhibit DNA multiply ( resulting cell death)

USE – AMOBEIASIS, GIARDIASIS, H- PAYLORY INDUCED PEPTIC ULCER & ORAL


INFECTION.

SIDE EFFECT – dry mouth, metallic taste, GI disturbance, dark urine.

CONTRAINDICATION – METRONIDAZOLE has a DISULFIRAM like effect ( cause excess


vomiting ).

For pregnant & lactate mother.

METRONIDAZOLE potentiate anticoagulant effect WARFARIN (delay metabolism of


WARFARIN). Cause bleeding.

 PPF – is PENCILLIN group. Antibiotic used to treat different types (G+ and G-)
bacterial infection.

PROCAIN PENCILLIN is PENCILLIN G.

USE – PNEUMONIA, MENINGITIS

MOA – BACTRIOCIDAL( bacterial cell die from cell LYSIS ).

SIDE EFFECT – shock . ENCEPALOPATHY( pain parts of brain).

CONTRAINDICATION – AMINOGLYCOSIDE – SYNERGISM or same effect

 PROBENICIDES – delay excretion.

3.RX – BENZANTINE PENCILLIN 700,000 IV IM QD FOR 7 DAYS.

 COST

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 BENZANTILE PENCILLIN 1 VIAL = 15birr
 SYRINGE 5CC 2 birr
 SYRINGE 10CC 3 birr
 WATER FOR INJECTION 2

 SOLUTION
 BENZANTILE PENCILLIN = 1 vial = 2,400,000 IU
 (700,000×1×7/2,400,000) = 2.041 OR 2 vial
 In day we give ml of ( 1 vial = 10ml )
 ( 2.041 =? )
 (2.041×10 = 20)(20/7days) = 2.85 or 2 vial
 Or 1 vial = (10ml×700,000/2,400,000) = 2.9 or 2 ml
 How many syringe needed ?
 5cc = 7(day)×2(cost) = 14
 10cc = 2×3 = 6
 1 vial = (10ml or 10cc)
 Total amount of needed syringe 7(5cc) & 2(10cc) = 9 syringe needed.

EXPLANATORY

 BENZANTINE PENCILLIN – or it is PENCILLIN G it is available as salt like NA, K,


PROCAIN PENCILLIN & BENZANTINE PENCILLIN.
 PENCILLIN G OR BENZANTINE PENCILLIN orally inactive due to the acid.
 PROCAIN PENCILLIN & BENZANTINE salts are intermediate and long acting
respectively and salts absorbed from the muscle slowly.
 Is PENCILLIN group, antibiotic used to treat different types (G+ and G-) bacterial
infection.
 BENZANTINE PENCILLIN is PENCILLIN G.
 USE – PNEUMONIA, MENINGITIS.
 MOA – BACTERIOCIDAL(bacterial cell die from the cell LYSIS ) .
 SIDE EFFECT – shock, ENCEPALOPATHY (pain parts of brain.
 CONTRAINDICATION – AMINOGLYCOSIDE – SYNERGISM or same effect.
 PROBENICIDES – delay excretion.

4. RX – KETOCONAZOLE 200mg PO daily for 14 days.

ANTIACID – 2TSP PO TID for 7 days.


FESO4 – 30mg PO HS for 30 days.
COST

KETOCONAZOLE 0.88cent
ANTIACID 22.40birr
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FESO4 0.40cent
SOLUTION

KETOCONAZOLE = we have both in (200mg and 400mg).

1×14 = 14 (14×0.88) = 12.32

ANTIACID = 1bootle = contain 200ml

= 1TSP =5ml

= 1TBSP = 15ml

Then 2TSP = 10ml

 2TSP(10ML×3×7) = 210ml but we have purchase 1bootle = 1×22.40 = 22.40


 FESO4 = 1×30 = 30 (30×0.40) = 12

EXPLANATORY

 KETOCONAZOLE – is AZOLE antifungal FUNGISTATIC.

Have antibacterial, antifungal activity.

It is IMIDAZOLE agent.

MOA – inhibit fungal (P450 enzyme or responsible for LANOSTEROL and ERGOSTEROL).

Inhibit MITOCHONDRIA

USE – used to topically systematic and only orally.

 Oral and vaginal CANDIDIASIS


 DERMATOPHYTOSIS

SIDE EFFECT – MENUSTRAL irregularities

 Loss of libido
 GYNACOMESTIA in male

CONTRAINDICATION – pregnancy, H2 – blocker, ANTIACID decrease absorption.

ANTIACID decrease absorption of KETOCONAZOLE have chelating effect. So taken by time


gap before & after 2hrs.

 ANTIACID – are weak inorganic base drug.

Which help to neutralize the acid content of the stomach.

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It contain AL(OH)3, MG TRICILCATE, MG(OH)3, CACO3, NAHCO3.

AL – only causes CONSTIPATION

MG – only causes DIARRHEA

So MG & AL are weak base. in our stomach we have strong base HCL then ( weak base +
strong base ) = salt + H2O + CO2.

Then neutralize ph -------+-------------

(< 7acidic ) 7 (> 7basic )

H2O

The water is found in ph of 7 or neutralize.

USE – bring down the percentage of acidity

 Prevent heart burn


 Prevent stomach ulcer.
 FESO4 – it increase immunity and it is used for MICROCYTIC anemia (chronic blood
loss, iron deficiency, & THALASSEMIA)

It is oral preparation

USE – treatment of iron deficiency or anemia, prophylaxis, pregnancy, lactation, infant


growing children, professional blood donor .

SIDE EFFECT – nausea, vomiting & metallic taste.

5.RX – METFORMIN 500mg PO QD for 2 month

ALBENDAZOLE 400mg PO QD for 3 month


CLOXACILLIN 500mg PO TID for 7 days ( is not correct we give it QID ).

SOLUTION

 METFORMIN = 1×60 = 60
 ALBENDAZOLE = 1×90 =90
 CLOXACILLIN = 4×7 = 28

EXPLANATORY

 METEFORMIN – BIGUANIDES- is suppress hepatic glucose out put

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is insulin sensitizers and used to for type 2DM patients.

Type 1- insulin Dependant or insulin deficiency

Type 2- insulin sensitizers or insulin resistance (it is not enough)

USE – treat down regulation of LDL & VLDL

MOA – increase insulin sensitivity

Decrease hepatic glucose production

SIDE EFFECT – hepatic toxicity, HYPOGLYCEMIC, DIARRHEA is common.

CONTRAINDICATION – for type 1 DM, pregnancy, breast feeding.

 ALBENDAZOLE – is ANTINEMATODES drug (GEOHELMINTHS).

or soil transmitted HELMINTHS.

Example – round worms, whip worms, pin worms, & hook worms.

NEMATODES – is round worms.

MOA – inhibit glucose uptake

 Inhibit MICROTUBULE
 It is vermicide

ALBENDAZOLE – is congener of MEBENDAZOLE & BENZIMIDAZOLE drug treatment of


CESTODE.

Vermicide – substance or agent kill worms.

VERMIFUGE – substance or agent expel worms.

CESTODES – is same us to tape worms.

 Example – TANIA SAGINATA (beef tape worm)


 TANIA SOLLIUM (pork tape worm)
 DIPHYLLOBOTHRIUM (fish tape worm)
 HYMENOLPESIS NANA (dwarf tape worm)

CONTRAINDICATION – for pregnant mother, (ALBENDAZOLE, IVERMECTIN,


MEBENDAZOLE) can not give.

Safe for pregnancy PEPARAZINE.

SIDE EFFECT – abdominal discomfort so give with HYOCINE


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 CLOXACILLIN – it is cell wall synthesis inhibitors.

And PENCILLIN group & antibiotic used to treat different types G+ & G- bacterial infections.

It is PENCILLIN resistance.

MOA – prevent PEPTIDOGLYCON

BACTERIOCIDAL (cell death)

SIDE EFFECT – shock, ENCEPALOPATHY (pain in parts of brain)

CONTRAINDICATION – AMINOGLYCOSIDE or SYNERGISM (the same effect)

PROBENCIDES – delay excretion

6.RX – INSULIN - 50AM

- 30PM

For 3 month

SOLUTION

= 50+30 = 80 (80×90/1000) = 7.2 or 7 vials

 How many syringe needed ?


 One syringe used to for three times then 3×90 = 180
 But we give only 10-15 syringe.

7. RX – DOXYCYCLINE 100mg PO BID for 7 days.

CIPROFLOXACILLIN 500mg PO stat


NICLOSAMIDE 2gm PO stat

SOLUTION

 DOXYCYCLINE = 2×7 = 14
 CIPROFLOXACILLIN = 1×1 =1
 NICLOSAMIDE = we have on the store 500mg then
 1gm = 1000mg
 2gm = 2000mg
 Then 2000/500 = 4 mg

EXPLANATORY

 DOXYCYCLINE – is group of TETERACYYCLINE

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Broad spectrum antibiotic Effective against aerobic & anaerobic microorganism & G+ & G-.

USE – treatment of respiratory tract infection, H- PYLORI induced peptic ulcer, PNEMONIA,
bronchitis, typhus, ACNE BULGARIES

MOA – inhibit protein synthesis & do not bind to mammalian 40s & 60s ribosomal unit.

SIDE EFFECT – orally can cause NVD EPIGASTERIA

 Burning STOMITES
 DECIDOUS teeth
 Longer use NEPHROTOXIC
 Renal toxic & FANCONI`S syndrome

CONTRAINDICATION – ANTIACID, trivalent & divalent molecule or preparation decrease


absorption by CHILATION.

Like (diary product, milk, curd, CA+, MG+, AL+ & FE+ ).

Enzyme inducer like BARBITURATE, PHYNITOIN reduce serum level of TTC.

TTC inhibit VIT - K producing intestinal flora. Thus can potentiate the anticoagulant effect of
WARFARIN

 CIPROFLOXACILLIN - is FLOROQUINOLONES or QUINOLONES family bactericidal.

it is 2nd generation of FLOROQUINOLONES the 1st generation is NALDIC ACID and the 2nd
generation is NORFLOXACILLIN & CIPROFLOXACILLIN.

USE – UTI, THYPHOID, bacterial DIARRHEA, GONORRHEA

MOA – inhibit bacterial DNA

Inhibit bacterial TOPOISOMERASE

SIDE EFFECT – GASTERO intestinal 5%

HEPATOXICITY

Cardiac, CNS, (headache & ISOMENIA)

CONTRAINDICATION – divalent & trivalent CATIONS can be ADMINSTERD 2-4 hrs and the
FQ first.

THEOPHYLLIN & CYCLOSPORIN – CIPROFLOXACILLIN inhibit of metabolism increase level &


increase toxicity.

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 NICLOSAMIDE – is used to treat tape worm & drug of choice for CESTODE (tape
worm)

CESTODE – (tape worm) found in the intestinal tract & definitive host.

EXAMPLE - TANEIA SAGINATA – (beef tape worm)

-TANEIA SOLIUM – (pork tape worm)

- DIPHYLLOBOTHRIUM – (fish tape worm)

-HYMENOLPESIS NANA – (dwarf tape worm)

NICLOSAMIDE is safe for pregnant mother.

MOA – inhibit glucose uptake

Inhibit MICROTUBELE

-The tablet should be thoroughly chewed or crushed & then swallowed with a small amount
of water.

CONTRAINDICATION – ALCHOL has a DISULFUREAS like effect or cause excess vomiting.

 PART 3.
 BIN CARD CALCULATION
 BASIC FORMULAS
CT= BB+QR-EB+L/A
CA= CT/RM-(DOS÷30.5)
SS= CA×LT
SMIN= (CA×LT)+SS
SMAX= SMIN+(CA×PP)
QO= CA×(LT+PP)+SS-(SI+SO)
 Physical inventory > balance = + signs
 Physical inventory < balance = - signs
 Transfer = - signs
 Donation = + signs

QUESTIONS

1. Calculate max stock level of TTC 250mg AMC from stock 1000 capsule of TTC from
stock & safety stock 2000 capsule of TTC 250mg LT & PP 2&6 month respectively.

SOLUTION –

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SMAX = SMIN + (PP×CA)

Then first we must find SMIN

SMIN = (LT×CA) + SS

SMIN = (2×1000)+2000 = 4000 capsule

Then replace to SMAX

SMAX = SMIN + (PP×CA)

SMAX = 4000+(6×1000) = 10,000 capsule

2. Calculate QO of NORFLOXACILLIN 400mg of opening stock 600. receiving stock


32,000. NORFLOXACILLIN 400 mg tablet LT & PP 3&6 month respectively. Loss /
adjustment = 0. DOS = 61 days. Stock in order = 0, closing stock = 300.
 If there is not stock in inventory (SI) we can use closing stock.

SOLUTION –

QO = CA×(LT+PP)+SS-(SI+SO)

FIRST WE MUST FIND –

 CT=beginning of balance + quantity of received – ending balance +loss/adjustment.

= 600+3200-300+0

= 32,300 tablet

 CA = CT/RM-(DOS÷30.5)

= 32,300/12-61÷30.5)

= 32,30 tablet

 SS = CA×LT

= 32,30×3 = 9690 tablet

 QO = CA×(LT+PP)+SS-(SI+SO)

= 32,30×(3+6)+9690-(300+0)

= 38,460 tablet

PART -4

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COMPOUNDING

BASIC PRINCIPLE –
 If all are ML we can use the better one
 If all are GM we can use by addition method (GM+GM)
 % can be expressed in 3 forms
- W/W – solid formula where expressed in the form of solid
- W/V - solid formula where expressed in the form of liquid
- V/V - solid formula where expressed in the form of liquid
- V/V = 2 WEEKS
- W/V = 3 WEEKS
1. LUGOOS SOLUTION

 POTASSIUM IODIDE ------------ 50gm×0.03 =1.5gm


 IODINE ---------------------------- 100gm×0.03 =3gm
 H2O --------------------------------1000ml×0.03=30gm

Send = 30ml

SOLUTION –

= RF = QN/MF or

= S /MF
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Then 30ml/1000ml = 0.03

Procedure -

 Tare the bottle 30ml


 Use glass type of mortal & pastel
 Measure POTASSIUM IODIDE in normal paper
 Tare 30ml of water
 Mix POTASSIUM IODIDE with small amount of water & dissolve
 Measure IODINE on watch glass
 Transfer into amber bottle
 Adjust the volume by water rinse

Labeling –

List of ingredient

 LUGOOS solution by 5% w/v of 30ml or 1000ml. (1.5×100/30)


 POTASSIUM IODIDE – increase solubility of iodine
 IODINE – API
 Action & use – treatment of goiter
 Dose & administration – as directed by physicians
 Preparation date – 30/03/12
 Beyond use date (ex–date) – discard after 3 weeks
 Prepared by – ATHSC
 Prepared at – THSC
 Storage - store in cool place
 Keep rich out of children & for internal use only.
2. CALAMINE LOTION

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 CALAMINE ---------------- 80gm×0.05 =4gm
 ZNO ----------------------- 80gm×0.05 = 4gm
 GLYCERINE -------------- 20ml×0.05 = 1ml
 BENTONATE ------------- 20gm×0.05 = 1gm
 CALCIUM HYDROXIDE --- 1000ml×0.05 = 50ml
Send = 50ml
SOLUTION –
= RF = QN/MF or
= S /MF
Then 50/1000 = 0.05

Procedure –
 Tare bottle 50ml & tare 50ml of water
 Measure CALAMINE on normal paper
 Measure ZNO on normal paper
 Then mix CALAMINE & ZNO on mortal & pastel
 Add BENTONATE
 Add GLYCERINE = 1ml or 20drops measure and add put
 Add CALCIUM HYDROXIDE solution measure & to mix small amount of (add to bottle)
 Adjust volume by CALCIUM HYDROXIDE rinse
 We can add GLYCERINE on the last because it is small amount.

LABELING –

LIST OF INGREDIENT
 CALAMINE lotion by 8% W/V of 50ml or 1000ml (4×100/50)
 CALAMINE – API & using of sun burning
 ZNO – astringent effect
 GLYCERINE – IMMOLIENT or attach
 BENTONIATE – suspending agent (for mixing)
 CALCIUM HYDROXIDE – solvent
 Action & use – use for itchy, dry skin, treatment of sun burn
 Dose & administration – as directed by physicians
 Preparation date – 26/03/12
 Beyond use date (ex–date) – discard after 3 weeks
 Prepared by – ATHSC
 Prepared at – THSC
 Storage - store in cool place
 Keep rich out of children & for external use only.
3. PEPERMINT SPIRIT

19
 PEPERMINT OIL -----------100ml×0.02 =2ml or 40drop
 ETHANOL 90% ------------- AD 1000ml ×0.02 =20ml

Send = 20ml

SOLUTION –

= RF = QN/MF or

= S /MF

Then 20/1000 = 0.02

Procedure –

 Dissolve the PEPERMINT OIL with equal amount of ETHANOL


 Shake it well
 Finally adjust the volume by 90% of ETHANOL V/V

Labeling –

List of ingredient -

 PEPERMINT SPIRIT by 10% V/V of 20ml or 1000ml (2×100/20)


 PEPERMINT – API
 ETHANOL – solvent
 Action & use – flavoring agent & carminative effect
 Dose & administration – as directed by physicians
 Preparation date – 26/03/12
 Beyond use date (ex–date) – discard after 2 weeks
 Prepared by – ATHSC
 Prepared at – THSC
 Storage - store in cool place
 Keep rich out of children & for internal use only.
20
4. PEPRMINT SPIRIT

 PEPRMINT OIL ---------100ml×0.02 =2ml or 40drop


 ETHANOL 97% ---------AD 1000ml =20ml

Send = 20ml

SOLUTION –
= RF = QN/MF or
= S /MF
Then 20/1000 = 0.02
If there is not 97% of ETHANOL we can use 90% by dilution method (to change 97%- 90%)
= C1×VI/C1 = C2×V2/C1
= V1 = C2×V2/C1 = 90%×20ml/97% =18.55 of 97% of ETHANOL
Then add water 1.45 because 20-18.5 =1.45 water if it is must be 20ml then it will be 90%.

Procedure –
 Dissolve the PEPERMINT OIL with equal amount of ETHANOL
 Shake it well
 Finally adjust the volume by 90% of ETHANOL V/V

LABELING –
 List of ingredient -
 PEPERMINT SPIRIT by 10% V/V of 20ml or 1000ml (2×100/20)
 PEPERMINT – API
 ETHANOL – solvent
 Action & use – flavoring agent & carminative effect
 Dose & administration – as directed by physicians
 Preparation date – 26/03/12
 Beyond use date (ex–date) – discard after 2 weeks
 Prepared by – ATHSC
 Prepared at – THSC
 Storage - store in cool place
 Keep rich out of children & for internal use only.
21
5. ZINC OXIDE PESTE –

 ZNO ------------ 250gm×0.02 =5gm


 STARCH -------- 250gm×0.02 =5gm
 WHITE PETROLEUM --- 500gm×0.02 =10gm

Send = 20gm

SOLUTION –

= RF = QN/MF or

= S /MF

Then 20/1000 = 0.02

Procedure –

 Measure on normal paper ZNO & STARCH put in mortal & pastel
 Then mix both
 Measure WHITE PETROLEUM on wax paper (plastic paper) or we can use the paper by
sucking the WHITE PETROLEUM in small amount by softening the paper.
 Then put WHITE PETROLEUM on evaporating dish by using heat resistance beaker
 Then stir the WHITE PETROLEUM when it is melt
 It is PESTE so we must use hotly & then mix with ZNO & STARCH on mortal & pastel
 Transfer into ointment jar

Labeling –

22
List of ingredient -

 ZNO PATE by 25% W/W of 20gm or 1000gm (5×100/20)


 ZNO – API astringent effect
 STARCH – filter or diluents
 WHITE PETROLEUM – ointment base
 Action & use – for mild astringent & dermatological condition, psoriasis
 Dose & administration – as directed by physicians
 Preparation date – 26/03/12
 Beyond use date (ex–date) – discard after 3 weeks
 Prepared by – ATHSC
 Prepared at – THSC
 Storage - store in cool place
 Keep rich out of children & for external use only.
6. SULFUR OINTMENT

 Sulfur ---------100gm×0.02 =2gm


 Mineral oil -----100gm×0.02 =2gm
 White petroleum – 800gm×0.02 =16gm

Send = 20gm

SOLUTION –

= RF = QN/MF or

= S /MF

23
Then 20/1000 =0.02

Procedure –

 Weight (white petroleum, mineral oil, sulfur)


 Then put on ointment slap (glass chop up)
 Then geometrically mix (half)
 Transfer into ointment jar

Labeling –

List of ingredient -

 Sulfur ointment by 10% W/W of 20gm or 1000gm (2×100/20)


 Sulfur – API antibacterial, KERATOLYTIC, & ANTISCABIES
 Mineral oil - lubricant
 WHITE PETROLEUM – ointment base
 Action & use – ANTISCABIES, ACNE
 Dose & administration – as directed by physicians
 Preparation date – 30/03/12
 Beyond use date (ex–date) – discard after 3 weeks
 Prepared by – ATHSC
 Prepared at – THSC
 Storage - store in cool place
 Keep rich out of children & for external use only.

24
7. FESO4 SYRUP – USP

 FESO4 -------- 40gm×0.05= 2gm


 Citric acid ------ 2.1gm×0.05= 0.105gm
 PEPERMINT SPIRIT --- 2ml= 0.1ml
 Sucrose -------- 825gm×0.05= 41.25gm
 Purified water ----- 1000ml= 50ml

Send = 50ml

SOLUTION –

= RF = QN/MF or

= S /MF

Then 50/1000 =0.05

Procedure –

 Tare the bottle 50ml


 Weight (FESO4,CITRIC ACID, & SUCROSE)
 Then put into baker half
 Weight H20 50ml and put 25ml on beaker (half)
 Then put on water bath
 Then when it is cool put in on mortal & pastel
 Then transfer to tare bottle
 Weight PEPERMINT SPIRIT 1ml=20drop
25
0.1=?

(0.1×20)= 2drop and add

 Again put on beaker sucrose & H2O on water bath


 Then when it cool adjust volume by simple syrup

Labeling –

List of ingredient -

 FESO4 SYRUP by 4% W/V of 50ml or 1000ml (2×100/50)


 FESO4 - API
 Citric acid - antioxidant
 PEPERMINT SPIRIT – flavoring agent
 Sucrose – sweetening agent
 Purified water - vehicle
 Action & use – blood builder (HEMATINIC)
 Dose & administration – as directed by physicians
 Preparation date – 07/04/12
 Beyond use date (ex–date) – discard after 3 weeks
 Prepared by – ATHSC
 Prepared at – THSC
 Storage - store in cool place
 Keep rich out of children & for internal use only.
8. MAGNISIUM TRICILCATE MIXTURE OF ORAL
SUSPENSION

26
 MAGNISIUM TRICILCATE ----------50gm×0.05 =2.5gm
 LIGHT MGCO3 -----------------------50gm×0.05 =2.5gm
 SODIUM BI CARBONATE -----------50gm×0.05 =2.5gm
 CON. PEPERMINT EMULSION -----25ml×0.05 =1.25ml
 CHLOROFORM ------------------------500ml×0.05 =25ml
 WATER -------------------------------1000ml×0.05 =50ml

Send = 50ml

SOLUTION –

= RF = QN/MF or

= S /MF

Then 50/1000 = 0.05

Procedure –

 Tare the bottle 50ml


 Weight (MG TRICILCATE, LIGHT MG, NACO3)
 Then mix on mortal & pastel
 Weight H2O 50ml & add small amount on mortal & pastel for mixing at least put in
25ml
 Transfer to tare bottle
 Add PEPERMINT EMULSION = 1.25ml
Then 1ml=20drop
1.25=?
(1.25×20) = 25drop or 20ml + 5drops
 Add CHLOROFORM 25ml
 Adjust the volume by water

Labeling –

List of ingredient -

 MG TRICILCATE SUSPENSION by 5% W/V of 50ml or 1000ml (2.5×100/50)


 MG TRICILCATE – API & ANTIACID
 LIGHT MG CARBONATE – API & ANTIACID
 NACO3 – API & ANTIACID
 CONC.PEPERMINT EMULSION – flavoring agent & carminative
 Chloroform water – flavoring, preservative, vehicle
 Action & use – treatment of DYSPEPSIA, ulcer
 Dose & administration – as directed by physicians

27
 Preparation date – 08/04/12
 Beyond use date (ex–date) – discard after 3 weeks
 Prepared by – ATHSC
 Prepared at – THSC
 Storage - store in cool place
 Keep rich out of children & for internal use only.
9. ORS –

 Sodium chloride -----------260gm×0.0025 =0.67gm


 Potassium chloride -------- 150gm×0.0025 =0.375gm
 Potassium citrate ----------- 290gm×0.0025 =0.725gm
 Glucose hydroxide ----------1350gm×0.0025 =3.375gm

Send = 5.16

SOLUTION –

= RF = QN/MF or

= S /MF

Then 5.16/2050 =0.0025

Procedure –

 Weight (NACL, K+CL, & K+CITRATE)


 Put into mortal & pastel & mix them, the mortal & pastel should be dried
 Then put in glucose hydroxide small amount & mix it with them
28
 Transfer into paper socket

Labeling –

List of ingredient -

 ORS (oral REHYDERATION salt) by 12.98% W/W of 5.16gm or 1350gm


(0.67×100/5.16)
 Sodium chloride – API
 Potassium chloride – co-solvent
 Potassium citrate -
 Glucose hydroxide – sweating agent, supplement during hypoglycemia
 TRISODIUM chloride – control flocculation
 Action & use – used to replenish electrolyte
 Dose & administration – as directed by physicians
 Preparation date – 08/04/12
 Beyond use date (ex–date) – discard after 3 weeks
 Prepared by – ATHSC
 Prepared at – THSC
 Storage - store in cool place
 Keep rich out of children & for internal use only.
10. WHITE FIELD –

 BENZOIC ACID --------------60gm×0.025 =1.5gm


 SALISYLIC ACID -------------30gm×0.025 =0.75gm
 EMULSIFYING WAX ----------910gm×0.025 =22.75gm

Send = 25gm

SOLUTION –

= RF = QN/MF or
29
= S /MF

Then 25/1000 =0.025

Procedure –

 Measure on normal paper BENZOIC ACID & SALISYLIC ACID


 Put in mortal & pastel. Mix it them
 Then we must work or prepare EMULSIFYING WAX

Emulsifying OINTMENT –

 WHITE SOFT PARAFFIN ----------500gm×0.025 =12.5gm


 EMULSIFYING WAX ---------------300gm×0.025 =7.5gm
 LIQUID PARAFFIN ----------------200gm×0.025 =5gm

Send = 25gm

SOLUTION –

= RF = QN/MF or

= S /MF

Then 25/1000 =0.025

Procedure –

 Measure white soft paraffin & emulsifying wax


 We have only white soft paraffin we have not emulsifying wax so we can use white
soft paraffin in to two parts (white soft paraffin + emulsifying wax(white soft paraffin).
 Add liquid paraffin
 All melting points are the same so we can put all on the water bath
 Then melt & stir when it cool
 Finally the result will be emulsifying ointment

Then return to the first procedure –

 We work emulsifying ointment 25gm. we need only 22.75gm then again we weigh.
 Then mix emulsifying ointment from BENZOIC ACID & SALISYLIC ACID half. It does
not pebble it must be only soft. Then mix with equal parts.

Labeling –

List of ingredient -

 WHIT FIELD BY 6% W/W of 25gm or 910gm (1.5×100/25)


30
 BENZOIC ACID – MILD ANTIFUNGAL
 SALISYLIC ACID – KERATOLYTIC effect
 Emulsifying wax – ointment base
 Action & use – anti fungal
 Dose & administration – as directed by physicians
 Preparation date – 26/03/12
 Beyond use date (ex–date) – discard after 3 weeks
 Prepared by – ATHSC
 Prepared at – THSC
 Storage - store in cool place
 Keep rich out of children & for external use only.

PART – 5

ALL TYPE OF EXERCISE

EXERCISE – 1

Knowledge Assessment Booklet for Pharmacy


Technology
1. D Which one of the following is NOT true about the role of DTC?
A. Giving information with regard to drugs
B. Teaching /coaching of health professional
C. Upgrading drug information services
D. dispensing of pharmaceutical products to the patients

2. D One of the following is an API of ‘’Khat’’?


A. Nicotine
B. Caffeine
C. Reserpin
D. Cathionine

3. D In which type of container is a medication ampoule is formed?


A. well closed container
B. sealed container
C. air thigh container
31
D. closed container

4. D If the volume of the drug is 5 L and the strength is 1/10 % .what is the weight of the
drug?
A. 0.5 gm
B. 5 gm
C. 50 gm
D. 500 gm

5. D How many volume of water is added to 1500 ml of 75 % ethanol to make 50 %?


A. 1000 ml
B. 7500 ml
C. 750 ml
D. 2250 ml

6. C Which one of the following antihypertensive drugs is used for emergency hypertensive?
A. Methyl Dopa
B. Enalapril
C. Hydralazine
D. all

7. C Which one of the following dosage form is directly administer to the blood vessels?
A. Enteral
B. Vaginal
C. Parentral
D. Rectal

8. C What is the weight of zinc oxide in which the volume is 4000 ml and strength is 8 %
w/v?
A. 32 gm
B. 0.3 gm
C. 320 gm
D. 32 gm

9. C Which one of the following is drug supply quantification is precise to predict the future?

32
A. Morbidity Method
B. Adjusted consumption method
C. Consumption method
D. quantitative method

10. B What is the maximum consumption of amoxycilline 500 mg capsules in which safety
stock is 2000 capsules and average consumption is 1000 capsules and lead time and
procurement period is 2, 6 months respectively?
A. 20,000 Capsules
B. 10,000 capsules
C. 30,000 capsules
D. 5000 capsules

11. D One of the following pharmaceutical products auxiliary labelling of ‘’ SHAKE BEFORE
USE ‘’ is not needed?
A. Emulsion dosage form
B. suspension dosage form
C. Praffine lotion
D. solution

12. A which one of the following is not parentral route

A. Sublingual
B. Intravenous
C. Subcutaneous
D. Intramuscular

13. B Pharmaceutical Products Labelling contains all of the following information ,EXCEPT

A. Patient name
B. martial statues
C. API name
D. age and sex

14. A Which one of the following is calcium channel blocker?

A. Nefidipine
B. Propranolol
33
C. captopril
D. Hydralazine

15. B Which one of the following NSAID has no anti-inflammatory effects?

A. Diclofenac
B. Paracetamol
C. Indomethacin
D. Ibuprofen

16. B Mr. X is diabetic patients and his physician prescribes Metformine 500 mg po bid for 60
days. How many tablets of Metformine do you dispense?
A. 200 Tablets
B. 120 Tablets
C. 150 Tablets
D. 100 Tablets

17. A When 40 mg of a drug present in 1 ml, in what amount of ml will found in 120 mg of a
drug present?
A. 3ml
B. 4 ml
C. 5 ml
D. 6 ml

18. C One Box of a given drugs contains 24 Bottles of drugs. One Bottle contains 100 ml and
this 100 ml also contains 3 gm .So, how many grams are found in one Box?
A. 70 gram
B. 24 gram
C. 72 gram
D. 300 gram

19. D Which pharmaceutical products preparation contains large amount of powder?

A. Ointment
B. Creams
C. Jellies
D. Paste
34
20. A Which information tells /gives detail about efficacy of the drugs?

A. Expire date
B. Quantity of a drug
C. product name
D. batch number of a drug

21. B One of the following is an effective procurement ?EXCEPT

A. Procure the right drug in the right quantity


B. procure with the highest possible purchase prices
C. ensuring safety, efficacy and quality of drugs
D. procure pharmaceutical products by generic name

22. F One of the following is criteria for selection of essential drugs during procurement?
Except
A. Selecting with adequate quantity
B. selecting with proven efficacy and safety
C. selecting with cost effectiveness
D. Selecting with adequate quality
E. selecting with generic name
F. None

23. ? Which one of the following is used when stock out is occurred or when there is low
level of pharmaceutical product is occurred?
A. Annual purchasing
B. Schedule purchasing
C. perpetual purchasing
D. pushing system

24. A which one is the process of deciding the type of needed drug products , depending on
the prevalence of health problems (disease pattern)
A. selection
B. procurement
C. distribution
D. patient drugs use
35
25. D Which one is the systems that manage, properly selection of the products of
pharmaceutical products and sources of drug supply?
A. Logistic and management system
B. Drug and supply management
C. DTC
D. A and B

26. E Which one of the following is an advantage of plastic over glass types of mortar and
pestles?
A. can be easily sterilized
B. can not transmit light
C. can be easily washable
D. can be inspect the internal content
E. all

27. B Which one of the following drugs has narrow spectrum drugs?

A. Ampicillin
B. Isoniazide
C. Ceftraxone
D. Pencilline

28. A Which one of the following is semi solid emulsion?

A. Cream
B. ointment
C. paste
D. jelly

29. D How many grams of Zinc chloride should be used in the preparation of 5L of mouth
wash and its concentration is w/v of zinc chloride?
A. 10 Gram
B. 5 Gram
C. 0.5 Gram
D. 50 Gram

30. C It is route of drug administration which is refers to injectables dosage form?


36
A. Rectal
B. Nasal Spray
C. Parentral
D. Inhalation

31. C One of the following is not the effect of drug acting in sympathetic nervous system?

A. Dilation of the pupil


B. Increase blood pressure
C. Decrease heart rate
D. Increase alertness

32. A are glass ampoule sealed by fusion?

A. Hermetically sealed container


B. Well-closed container
C. Air-Tight container
D. Securely closed container

33. B Which one of the following are not good dosage form preparations for water insoluble
drugs?
A. Elixir
B. Syrups
C. suspension
D. Emulsion

34. D The following are thickening agent, except.

A. Alginate
B. Tragacanth
C. Bentonite
D. Sodium Bentonite

35. ? is a bleached cotton cloth of plain weave?

A. Gauze pad
B. Bandage
C. Oiled Silk
D. Absorbent muslin
37
36. B Which one of the following HAART/ART drugs is not available as FDC (Fixed Dose
Combination)?
A. AZT+3TC+NEV
B. TDF+3TC
C. TDF+3TC+EFV
D. TDF+3TC+NEV

37. C The following are true about EBOLA?

A. The rate of mortality from Ebola is 100 %


B. It has an incubation period of 2 -21 days
C. An experimental drug Zmapp given to infected individuals has shown a
promising therapy.
D. Infected individuals have high fever, Flu-Like symptoms, body cavity bleeding,
Respiratory collapse, nervous system effects and organ failure.

38. B Which one of the following drugs is in effective taken by mouth?

A. Probenecid
B. Heparin
C. Ciprofloxacilline
D. Aspirin

39. C How many grams dextrose is required preparing 4000 ml of 8 %(w/v) solutions?

A. 3.2 g
B. 32 g
C. 320 g
D. 3200 g

40. C Which one of the following quantification methods gives the most accurate methods for
future needs?
A. Morbidity methods
B. Adjusted consumption methods
C. Consumption methods
D. Service level quantification

38
41. B Calculate the maximum stock level of TTC 250 mg capsules with the safety stock 2000
capsules and average monthly consumption adjusted from stock 1000 capsules .The lead
time and procurement period is 2 months and 6 months respectively ?
A. 4000 Capsules
B. 10,000 Capsules
C. 12,000 Capsules
D. 24,000 Capsules

42. A Which one of the following is NOT true about Tetracycline Capsules?

A. It is bactericidal agent
B. Cause liver damage in pregnancy
C. bind with 30 S ribosomal sub unit and affect protein synthesis
D. causes discoloration of bones

43. C A drug with diuretic effects and also used in the treatment of glaucoma?

A. Hydrochlorothiazide
B. Frusemide
C. Acetazolamide
D. Enalapril

44. C Based on the clinical evidence it is mostly used in the emergency causes for flatulence
due to abdominal destination and used as an antidote for chemical ingestion?
A. Oral Dehydration salt
B. Loperamide
C. Activate Charcoal
D. Tetanus anti Toxoide

45. A What is the final concentration if 100 ml of 10 % of certain solution is diluted to 240 ml
with water?
A. 4 %
B. 5%
C. 6%
D. 7%

39
46. D What amount of water is added in 50 ml of 90 % alcohol to produces 30 % strength
alcohol?
A. 120 ml
B. 130 ml
C. 140 ml
D. 150 ml

47. A How much amount of alcohol is taken from a pack containing 1 Litter of 95 % strength
to prepare 50 ml of 70 % strength of alcohol?
A. 37 ml
B. 38 ml
C. 39 ml
D. 40 ml
MATCHING

INSTRUCTION FOR MATCHING

1. There are 15 questions in this section


2. Match column A with column B .select the letter of the correct answer from column B and
write your answer in the provide spaces in the front of the number in column A.
3. If you want to change your answer place an “X” mark on your previous answer and write
your preferred answer.
4. A correct answer scores “1 mark” and incorrect answers scores “0’’ scores .No mark will be
given for a question if more than one answer is supplied.
5. Cheating is prohibited.
COLUMN “ A” COLUMN “B”

1. Q Effervescent Tablet A. Guafensine


B. Flexible to various situation
2. F Adjusted Consumption
C. Phenytoin
3. L Enteric coated Tablet D. Placebo

4. ? Dosage form of devoid active E. Simvastatin

ingredients F. complex and time consuming

40
5. N Pressurized dosage form G. cardiac failure
H. Narcotic
6. I Promotes stability
I. co-solvent
7. G Digoxin J. Migraine prevention

8. C Antiepileptic K. Psychotropic
L. Release in the intestine
9. B Myopathy (sever muscle pain)
M. Fluxotine
10. P Non-productive cough suppressant N. Aerosols

11. A Symptomatic relief of productive O. Salicylate (ASA)

cough P. Dextromethorphan
Q. produce solution
12. O Reyes Syndromes

13. ? Ergotamine tartrate

14. K Phenobarbitone
15. M SSRI

EXERCISE – 2
Hospital/community Pharmacy Assisting
(Level III)
Part 1. CHOOSE

Choose the best answer for the following questions


1. D Rx:- Amoxicillin 250mg/5ml suspension tidfor 7 days was prescribed for a patient. On hand
you will have 125mg/5ml suspension. How many ml you dispense?

A. 5ml, 200ml C. 10ml, 200ml


B. 5ml, 210ml D. 10ml, 210ml

2. C Which one of the following is psychotropic controlled drug?


A. Pethidine C. Diazepam
B. Tramadol D. Morphine

3. B Which one of the following is not controlled drug?


A. Pethidine B. Amitryptiline
41
C. Morphine D. Diazepam

4. D Which one of the following is the same properties about traditional drug and modern drug
A. More people choose this medication C. Cost saving medication
B. Approves scientifically D. Treats patients

5. B Rx:- Co-trimoxazole 960mg Qod for 2 months. On hand tou will have 480mg Co-
trimoxazole. So, from many tablets you disponse for 2 months.
A. 120 tablets of 480mg Co-trimaxazole
B. 60 tablets of 480mg Co-trimaxazole
C. 90 tablets of 480mg Co-trimaxazole
D. 60 tablets of 960mg Co-trimaxazole
6. B Rx:- Antacidsuspension 10ml tid for 1 month.How many bottles you dispense for 1 month?
On hand you will have antacid suspensions which contain 200ml.

A. 4 bottles C. 6 bottles
B. 5 bottles D. 7 bottles

7. B A suppository which is inserted to the vaginal is known as


A. Rectal supposition C. Bolus
B. Pessaries D. Enemas

8. B Vaginal agent solution preparation


A. Enemas C. Pessaries
B. Douchase D. None

9. D False about o/w emulsion


A. External phase is water
B. Can conduct electric current
C. Internal phase is oil
D. Greasy by nature
10. A True about pharmaceutical spirit except:
A. Sweetening agent
B. Contain Alcohol and Volatile oil
C. Aromatic water
D. Pharmaceutical aid solution
11. D What is the role of drug and therapeutic committee in hospital
A. Selection of drug
B. Editing of hospital formulary
C. Disposing of expire drug

42
D. All
12. A Which one of the following drug has disulfirum like action?
A. Metronidazole
B. Chloramphenicol
C. Amoxicillin
D. Tetracycline
13. A Which preparation has high concentration of sugar

A. Syrup C. Spirit
B. Elixir D. All

14. B Identity the non-hormonal contraceptive methods

A. Combined oral contraceptive C. Levenorgestrol only


B. IUCD D. None

15. A Which one study about dosageforms

A. Pharmaceutics C. physical pharmacy


B. Pharmacology D. None

16. A The continuous process of drug receiving, storing and stock controlling

A. Distribution C. Selection
B. Procurement D. None

17. A Which drug need to store in refrigerator

A. Insulin C. Amytriptylline
B. Diclofenac D. None

18. D Which one is a homogenesis phase

A. Suspension C. Cream
B. Ointment D. None

19. D One is not traditional medicine

A. Acunpacture C. Homopathy
B. Ayurveda D. None

20. D Semi solid preparation which contain more powder

A. Ointment C. Jelly
B. Cream D. None
43
21. ? An intravenous 600 mg quinine in 600 mL 5% dextrose in saline
drops dropsis ordered to run for four
A._38 A._162.5
min drip min
drops
hours. Calculate the rate of flow in (given 1 mL= 15 )
drops minute min drops
B._900 B._
min min

22. C Suppose you receive a prescription with an order for drug “X” 500 mg tab po bid for the first
3 days q.d. for the next 3 days and qod for the last 4 days. How many tabs of the drug with the
given strength should be dispensed for the patient?
A. 15 B. 25 C. 11 D. 10

23. A Is potentially lifesaving pharmaceutical products


A. Vital products C. Non-essential products
B. Essential products D. None of the above

24. B ‘’three times aday ‘’ is equivalent meaning to:


A. q.i.d C.__b.i.d
B. t.i.d D.__ p.r.n

25. D The amount of drug taken at one time


A. Dosage regimen C.__Daily Dose
B. Total dose D.__Single dose

26. A The process of combining liquid with a solid form of medication, so that the
medication is used is called .

A. Re-constitution C.__Calibration
B. dilution D.__Concentration

27. B How many grams of drug are in 480 mL of docusate sodium syrup 60mg /15mL
A. 28.8g C. 0.192g
B. 1.92g D. 2.88g

28. A Drugs that help to remove any thick tenacious mucus from the respiratory passages
A. Mucolytics C. Cough suppressant
B. Expectorants D. Antitussive

29. A Metabolism (biotransformation) of a drug can occur in:


44
A. Liver C. Kidney
B. GI tract D. All

30. A The antidote of Pracetamol toxicity is

A. N-acetyl cysteine (NAC) C. Physostigmine


B. Naloxone D. Flumasenile

31. B Which one of the following is notantiprotozoa drug


A. Tinidazol D. Chloroquine
B. Alebendazol E. Tetracycline
C. Diloxinate furoate

32. D Nightmares or strange dreams the side effect of


A. Abacavir C. Tenofovi
B. Neverapine D. Efavrenz

33. C How many antiretrovirals should be taken in order to prevent resistance and improve the
effectiveness of a regimen for a significant period of time?
A. At least 1 C. At least 3
B. At least 2 D. At least 4

34. A Protease inhibitors of Antiretroviral Drugs


A. Lopinavir C. Tenofovir
B. Lamivudine D. Efavirenz

35. A Which of the following is proton pump inhibitor used to treat peptic ulcer disease
A. Omeprazole C. Ranitidine
B. Cimetidine D. Famotidine

36. A ...................is needed to combat peripheral neuritis associated with INH therapy.
A. Pyridoxine (VIT B6) C. Folic acid
B. Vitamin B12 D. Niacin

37. C How many 250mg capsules are needed to fill the following prescription? "Amoxicillin 500 mg tid
for 10 day."

A. 20 B. 40
45
C._60 D._80

38. A ---------------is a liquid in liquid dispersion system


A. Emulsion C. Solution
B. Suspension D. All are answe

39. E Items is not need freezing or refrigeration


A. Insulin D. Hepatitis B vaccines
B. Ergometrine E. None of the above
C. Blood product

40. B Frequently picked item should be stored on_______

A. Lower level shelves


B. Middle level shelves
C. a Higher level shelves
D. All are correct

41. D A rectal suppository is used to treat a fever. This would represent what type of drug
delivery?

A. Parenteral and local C. Enteral and local


B. Parenteral and systemic D. Enteral and systemic

42. C Most medicines are made up of the active pharmaceutical ingredient (API) and
various excipients. Which one of the following is NOT a possible justification for formulating
medicines in this way?

A. The excipients stabilise the API so that it does not degrade appreciably before administration
B. The excipients reduce the possibility of the API irritating the body
C. The API and the excipients each exert a pharmacological effect
D. The API is too potent to use undiluted

43. A Which of the following provides the best definition of pharmaceutics?


A. It is the study of dosage form design, including associated manufacturing techniques
B. It is the study of the effect that drugs have on the body
C. It is the study of the effect that the body has on drugs
46
D. It is the study of how drugs can be chemically synthesised

44. B Which of the following formulations would not be applicable to ocular


administration?

A. Solution C. Suspension
B. Liniment D. Ointment

45. A Drugs can be order by:

A. Prescription C. Orally
B. Telephone D. All are answers

46. D Is not the correct designation in PTC committee is:


A. Chair person- medical director D. Secretary – head of pharmacist
B. Administrator-as member E. all are correct
C. Chair person – Sub – specialist

47. C At time of counseling of patients communicating language should be in

A. Dispenser language D. Hospital pharmacist language


B. Prescriber language E. All are correct
C. Patient language

48. B The process of preparing and giving out medicine to a named person on basis of prescription or non-
prescription is:

A. Drug distribution D. Community pharmacy


B. Drug dispensing E. Clinical pharmacy
C. Hospital pharmacy

49. C The drugs, which are helpful to increased passage of stool or softening it.

A. Antiacids C. Laxatives
B. Emetics D. None

50. B One of the following drug is used In the treatment of amebiasis, giardiasis,
trichomoniasis a

anaerobic bacterial infections.


47
A. Thiabendazol C. Albendazol
B. Metrindazol D. All of the above

51. B Which one of the following hormones should by injected during delayed labour is:
A. Ergometrine C. Insulin
B. Oxytocin D. Prostaglandin

52. D Which one of the following statement does not require special storage condition ?
A. Vaccines C. Combustibles
B. Poisons D. None

53. B Which one of the following is emergency contraceptive?

A. IUCD B. (POSTPILL)Diethylstilbostero

C. Norplant D. all

54. A Constipation is the side effect of

A. Al (OH) 3,
B. Mg (OH) 2,
C. NaHCO3.,
D. all

48
49
Pharmacy technology services model assessment from level I – level IV

55. C Successful eradication of H. pylori (80-90%) is possible with


A. Omeprazol, Clarithromycin ,Cimitidine ,Bismuth
B. Rantidin, Amoxicillin, Metrindazol, ,Bismuth
C. Omeprazol ,Clarithromycin ,,Metrindazole, ,Bismuth

D. Clarithromycin ,Cimitidine ,Omeprazole, ,Bismuth

Matching :Part I

A B

M 1.Trituration A. Right eye

L 2. Amber glass B. Prevent microorganism growth

K 3. Batch number C. Left eye

J 4. Flocculated suspension D. Sweetening agent

? 5. Drug therapeutic committee E. Prevent sunlight

I 6. Douches F. Traditional medicine

H 7. O/W emulsion G. Alcohol and Aromatic water

G 8. Spirit H. Emulsion that conduct electricity

F 9. Acupuncture I. Vaginal agent preparation

J. Highly sedimented preparation

B 10. Preservative K. Rename and known the product

C 11. O.L (0.S)(O’culus lae’vus) L. To protect the product from light

O 12. Disinfectant M. To make compounding

R 13. Vaginal suppository N. Dispersed material system

A 14. OD (Oculus dexter) O. Remov microbes from the object

D 15. Sucrose/Sackherine P. After meal

1
Pharmacy technology services model assessment from level I – level IV

Q 16. Rectal suppository Q. Annusol

Y 17. Enema R. Pessary

N 18. Suspension S. Transmitted generally by fecal route

P 19. PC T. Caused by entamebahistoletica

S 20. Giardiasis U. Blood thinner or not given to pregnant

T 21. Ameobiasis V. Antiprotzoal drug

U 22. Warfarin W. Formation of blood clot inside blood vessel

V 23. Metronidazole X. Uncontrolled bleeding

X 24. Blood disorder Y. Cleansing for rectal

W 25. Thrombosis Z. Cotrimoxazole

Z 26. Pneumonia

Part II

A B

F 27. B-blocker A. Ceftriaxone

M 28. NSAID B. Captopril

N 29. Antihistamine C. Atropa belladonna

B 30. ACEIS D. Hard paraffin

O 31. First generation cephalosporin E. Frusemide

K 32. Antifungal drug F. Propranolol

H 33. Antifungal drug safe for children G. Ketamine

L 34. Osmotic diuretics H. Griseofulvin

2
Pharmacy technology services model assessment from level I – level IV

E 35. Loop diuretics I. Metronidazole

P 36. Viscosity enhancer J. Mebindazole

J 37. Anthelmentic K. Ketoconazole

G 38. Anesthetic drug L. Mannitol

D 39. Ointment base M. Piroxicam

C 40. A leaf which dilate pupil N. Chlorpheniramine

Q 41. Malaria O. Cephalexin

R 42. Codeine P. Methylcellulose

S 43. USP Q. Cincona bark

T 44. Activated charcoal R. Opoid drug

U 45. Paracetamol S. United state of pharmacopeia

T. Antiflatulant

U. Antipyretic analgesics

V. ORS

W. Hydralazine

Part III

A B

L 68. Phase inversion A. Formaldehyde

M 69. Chlorpromazine B. Quality control assurance

N 70. Blister/strip packaging C. Flammable

3
Pharmacy technology services model assessment from level I – level IV

R 71. Type II diabetes mellitus D. Leak test

Q 72. Not traditional medicine E. Rapid onset faction

P 73. Sweetening agent F. body language

J 74. Paste G. Lead time

W 75. Phenytoin H. Pyrogen free

K 76. Pharmacist I. Body effect by the drug

E 77. Irrigation fluid J. An ointment have high powder


content

? 78. Clonazepam K. Drug dispensing

F 79. Non-verbal communication L. Emulsion

G 80. Time from order to receive M. For schizophrenia

D 81. To check leak of ampoule N. For tablet

O 82. Parentral preparation O. Pyrogene free

B 83. Principle of good manufacturing practice P. Sucrose/ Saccharin

C 84. Label for dangerous product Q. Implantation

A 85. Used to sterilize 500 m R. Metformin

U 86. Use a to sterilize heat sensitive product T. Lead lime


and material U. Filtration
sterilization
V. Phenytoin

W. Treat epilepsy

Part IV

4
Pharmacy technology services model assessment from level I – level IV

L 87. Anaphylactic shock A. Amoxacillin + clavulanic acid

G 88. Over the counter B. Antidote for paracetamol

J 89. Opportunistic infection C. Analgesics antipyretics

A 90. Augmentin D. Drop

C 91. Paracetamol E. Room temperature

M 92. Atropine F. To treat Parkinsonism disease

H 93. Metronidazole G. Dextrometorhan

K 94. QD H. Disulfiram like reaction

D 95. Gtt I. Aerosol

F 96. Levedipot carbidipa J. Herpes zoster

E 97. 15oc – 25oc K. Every day

B 98. N-acetylcysteine L. Adrenaline

N 99. Tablespoonful M. Antidote for malathion

R 100. Gown N. 15ml

Q 101. Vaginal suppository O. Liver inflammation

S 102. Thalidomide P. At once

P 103. Stat Q. Pessary

O 104. Hepatitis R. Personal protection

T 105. Affect bioavailability S. Teratogenic

U 106. NSAID T. First pass effect

5
Pharmacy technology services model assessment from level I – level IV

I 107. Pressurized U. Indomethacin

V 108. Methyldopa V. Safe for pregnancy

W 109. Codeine W. Opioid drug

X. Cool temperature

Part V

E 110. Chelating agent A. Diazepam, clonazepam

D 111. NNRT B. – 15oc to 0oc

B 112. Deep freeze C. Tablet

C 113. Binder D. Nevirapine, efavirenz

A 114. Anticonvulsant drug E. EDTA

EXERCISE – 3
LEVEL THREE PHARMACY THEORY EXAM CERTIFICATE OF COMPETENCY

JULY, 2019

2ND VERSSION

1. C One of the following is true about traditional medicines.


A. They are more pure than modern medicine and have precise dose.
B. They are always safe medicines.
C. They are more accessible to the majority of the population in developing
countries
D. They are scientifically proved to be ineffective.
2. B According to the FMHACA editions, one of the following is controlled drug .
A. Phenytoin
B. Phenobarbitone
C. Carbamazepine
D. Amitriptylline

6
Pharmacy technology services model assessment from level I – level IV

3. B Ato Abebe is a 50 kg adult on Griseofulvin 1000 mg therapy for Dermatophyte scalp


infection. he is taking 20mg/kg po daily for 1 month hence how many tablet of 250 mg
should you dispense to him ?
A. 60 tablets
B. 120 tablets
C. 30 tablets
D. 100 tablets
4. B One of the following is less relevant advice about infection control and prevention.
A. Hand washing is important before and after contact.
B. Contaminated instruments and equipment should not be confined to a well
designated contaminated zone.
C. In disposing infectious and hazardous wastes, personal protective equipment must be
worn.
D. Disposal of waste should be done safely in accordance with organizational policies
and procedures.
5. A One of the following is true about anti malarial drugs?
A. Arthmeter + Lumefantrine are drug of choice for plasmodium falciparum
species.
B. Pyrimetamine + Sulfamethoxazole (Fansider) is currently the best drug.
C. Chloroquine is used for severe and complicated malaria.
D. Quinine is drug of choice for radical cure of vivax species.
6. B One of the following is true about suspension
A. it is less stable than solution
B. it needs shaking before use
C. it can be given through intravenous route
D. It is homogenous

7. B The consumption for ciprofloxacillin 500 mg tablets in Gondar hospital for the last
seven months was 800,000 tablets. Assuming that there were 61 days of stock out, calculate the
average monthly consumption of ciprofloxacillin 500mg tablets in the last seven months in
Gondar Hospital.

A. 240,000 tabs C. 120,000 tabs

B. 160,000 tabs D. 150,000 TABS

8. B One of the following could be unnecessary to especially consider when dispensing a


drug to an adult female

A. Pregnancy C. Lactation

7
Pharmacy technology services model assessment from level I – level IV

B. Marital status D. Oral contraceptive pills (OCP) use

9. A A 70 year old man is prescribed with Amoxicillin 500 mg capsule PO TID for 10
days. If you have Amoxicillin 125mg/5ml suspension, the unit dose and total dose are _____and
_______respectively.

A. 20 ML and 600 ML C. 1O ML and 600 ML

B. 20 ML and 300 ML

10. B Weizero Alemitu is a 35 years old hypertensive patient she is in her third trimester.
Which drug is relatively safe for her?

A. Atenolol C. Nifidipin

B. Methyldopa D. Enalapril

11. C Which of the following is the main body of a prescription?

A. Sigma and Signature C. Inscription

B. Superscription D. Subscription

12. C Anti-TB drug which develops peripheral neuropathy as its main side effect along
with its prophylaxis is?

A. Pyrazinamide with Vitamin B1

B. Rifampicine with Vitamin D

C. Isoniazide with Vitamin B6

D. Ethambutole with Vitamin C

13. B Which of the following rout of administration has slow onset of action?
A. Sublingual B. PO C. Inhalation D. IV

14. C One of the following is a correct match.


A. Dry Heat Sterilization _____________ Hot Water

B. Radiation sterilization ____________ Ethylene Oxide

C. Steam Sterilization ______________ Autoclaving

8
Pharmacy technology services model assessment from level I – level IV

D. Chemical Sterilization ___________ Beta Rays

15. C One is True Description of storage conditions.


A. Refrigeration ____________ below -18 centigrade

B. Cool or Cold Place _________ from 18 centigrade to 25 centigrade

C. Room temperature _______ from 15 centigrade to 25 centigrade

D. Deep freezer __________ at -4 centigrade

16. A To get a quality pharmaceutical product, one of the following is less relevant to
consider.

A. The quality of advertisement about the product

B. The quality of raw material

C. The quality of in- process during manufacturing

D. The quality of the finished product

17. B If the 90% ethanol and 60% ethanol are given, their proportion to prepare 300 ml
of 70 % is?

A. 200ml of 90% ethanol and 100ml of 60% ethanol

B. 100ml of 90% ethanol and 200ml of 60% ethanol

C. 150ml of 90% ethanol and 150ml of 60% ethanol

D. 84.6ml of 90% ethanol and 115.4ml of 60% ethanol

18. A One of the following is unrelated to the main responsibility of the quality control
department in pharmaceutical industry?

A. Physical inspection of containers of raw materials for damage

B. Ensuring the chemical and physical properties of raw materials

C. Checking the type and quality of raw materials on the label

D. Undergoing clinical trials to develop new drugs

9
Pharmacy technology services model assessment from level I – level IV

19. B Amoxicillin 500mg PO for TID for 7days. Based on this information, which of
the following is correct?

A. The frequency of dosing is 7 days

B. The route of administration is per oral

C. The route of administration is per rectum

D. The duration of treatment is TID

20. C One of the following abbreviations is correctly matched with its meaning.

A. Noct = at day time

B. QOD= four time a day

C. Stat = at once

D. AS= right ear

21. D One of the following is less important to consider as an objective of labeling


on a dispensed medicine.

A. To clearly indicate the patient how to take and store the medicine.

B. To clearly indicate the patient how and when the medicine should be taken or used

C. To clearly indicate the patient any warnings or precautions about the medicine

D. To clearly indicate the type of packaging material

Matching

1. A Antibiotic not given IV A. Benzathin penicillin


2. O A Laxative drug safe for children B. AS
3. R Family planning methods and STI prevention C. Methyl paraben
4. K Suppository Base D. Neverapine
5. Q Drug to treat diabetic mellitus E. Griseofulvin
6. D Examples of protease inhibitors (PIs) F. Rabbit test
7. M Pharmaceutical lubricating agent G. Ritonavir
8. I To treat Parkinsonism H. Amphotericin B

10
Pharmacy technology services model assessment from level I – level IV

9. E Antifungal drug safe for children I. Levodopa/carbidopa


10. F Detection of Pyrogen J. AU
11. J Both Ears K. Cocoa butter
12. L Non- Steroidal anti-inflammatory drug L. Diclofenac
13. H Both antifungal & antibacterial drug M. Magnesium stearate
14. P Loop diuretics N. Castor oil
15. C Preservative O. Glycerin suppository

P. Furosemide

Q. Metformine

R. Condom

11
EXERCISE - 4

Knowledge Assessment questions Pharmacy Technology

1. C Which one of the ff statements is true about the rationale of small-scale


compounding of pharmaceutics?
A. Many patients are allergic to excipients in commercially available products
B. Many patients need drug strengths that are commercially available
C. Many patients need dosage forms that are commercially available
D. Adults medications must be prepared as gumdrops and lollipops

2. D Which one of the ff is the advantage of having essential drug list in a give
health facility?

A. Increase number of stock items in the store


B. Increase the cost of stock items
C. Increase number of items prescribed
D. Increase patient adherence

3. D A pharmacy technician has reconstituted single-dose vials of antibiotics using


closed system transfer methods. The risk involved in such simple admixture
compounding process is classified as;

A. Medium-risk compounding
B. High-risk compounding
C. Low-risk compounding
D. Non-risk compounding

4. B Which one of the ff methods is used to detect the presence of pyrogenic


substances in a given pharmaceutical product

A. Clarity test
B. Rabbit test
C. Stability test
D. Leaker test

5. C Which one of ff anticancer drugs is plant origin?

A. Methotrexate
B. Dactinomycin
C. Vincristine
D. Procarbazine

6. D A patient on ART has anemia, neutropenia, nausea, insomnia. Which one of


the following are ART drugs is the main cause of the above adverse effects?

A. Lamivudine (3TC)
B. Stavudine (D4T)
C. Tenofovir (TDF)
D. Zidovudine (AZT)

7. A Which one of the ff statements refers to the rationale combining of anticancer


drugs?
A. Provide synergism results/effect
B. Provide radical cure treatment
C. Provide stimulation of immune system
D. Provide stimulation of Cell proliferation
8. C A liquid medicine is supplied in concentration of 20mg /5ml. a patient requires
40mg orally three times daily for five days and then 20mg once daily for five
days. Which of following is the volume of liquid medicine that you will need to
dispense?

A. 600ml
B. 300ml
C. 200ml
D. 60 ml

9. C Mr .birhanu a pharmacy case team leader at the referral hospital has unique
communication style that recognize every once needs are important witch one of
the following is the communication style of mr.birhanu?

A. Aggressive communication style


B. Passive communication style
C. assertive communication style
D. passive aggressive communication style

10. C If you dissolve 40 mg of an ingredients in 4 ml of solvent what would be the


strength of the resulting solution expressed as mg/ml?
A. 3 mg/ml
B. 30 mg/ml
C. 10 mg/ml
D. 20 mg/ml

11. A 1% (W/W ) of Diclofenac means:


A. 1 gm of active ingredients (Diclofenac) in a total of 100 gm of the
mixture
B. 1 gm of active ingredients (Diclofenac) in 100 gm of the vehicle
C. 1 gm of active ingredients (Diclofenac) in a total of 100 ml of the mixture
D. 1 gm of active ingredients (Diclofenac) in a total of 100 ml of the vehicle

12. D Which one of the following is incorrectly matched?


A. Disinfectant : chemicals applied on inanimate objects for the purpose of
eliminating pathogens
B. Antiseptic: are chemicals that are applied on living skin to kill
microorganisms
C. Germicides: are chemicals capable of killing microorganisms
D. Bactericidal agents: are chemicals capable of killing diverse group of
microorganisms

13. C Which one of the following agent is potent protein synthesis inhibitor?

A. Cloxacillin
B. Ceftraxone
C. Clindamycin
D. PPF

14. E What measures do you recommended for your client who gets contaminated
with a blood HIV positive patient as a result of car accidents?

A. Washing with water alone


B. Using PEP
C. Using antibiotic
D. Using analgesics
E. All
15. D All of the following contributes for a risk to take place while operating in a
hospital setting? except
A. Wearing close shoes
B. Using apron
C. Using glove prior to operate
D. Managing open wounds using hands without glove during time of
emergency

16. A All of the following helps in maintaining good relationship with customer as
part of a good business practices? except
A. Neglecting the issue of customers
B. Developing and maintain close relationship with customers
C. Solving the issues of problems of customers as quick as possible
D. Work much to satisfy customers

17. D Which one of the following can be the key performances indicators of a
leader?
A. Demonstrate a negative influence on others
B. Refuse to accept idea from his colleagues
C. Makes soundly researched decisions
D. All

18. A During implementation of 5S in work place ,organization of necessary items in


going to be order and easy access is called

A. Sorting
B. Self –Discipline
C. Standardize
D. Systematize

19. A The best way of disposing unfit for use solid dosage form drugs:

A. Land fill
B. Burning in open air
C. Incinerate with high temperature
D. Re-use

20. D Risk factors that hinder change in an organization could be all of the following
except
A. Confusion / loss of confidence
B. Product /service delivery problems
C. Cost blow out
D. Cost minimization policy

21. A Which one of the following are not anti Helmentic drugs?

A. Metronidazole
B. Mebendazole
C. Niclosamide
D. Praziquantel

22. A One of the following not included in SMART objectives?


A. Objective should be small enough
B. Objective should be measurable
C. Objective should be time bound
D. Objective should be realistic

23. C What is the PH of 0.001 N HCL solutions?

A. 1
B. 2
C. 3
D. 4

24. B How many grams of 2.5 % Bethamethasone cream should be mixed with 640
gram of 0.25 % Bethamethasone cream to make 1 % Bethamethasone cream?

A. 180 gm
B. 320 gm
C. 360 gm
D. 100 gm

25. A Which one of the following does not belong to the main principle of effective
capacity building practice?
A. Respecting pre-existing capacities
B. Developing mutual respect
C. Maintaining pre-packaged ideas
D. Being responsive to context with in which capacity building programs suits
26. A Which one of the following categories of change involves work process
methods equipment

A. Technology
B. People
C. Competitors
D. Structure

27. B Which one of the following statement best describes the rational for combined
chemotherapy of tuberculosis?
A. Increase oral absorptions of ant mycobacterium drugs
B. Decrease mycobacterium drug resistances
C. Decrease adverse effect of anti mycobacterium drugs
D. Decrease the onset of antimicrobial biotransformation

28. B Which one of the following statement is TRUE about physical counting
A. Annual stock counting is suited to track down the source of discrepancy
B. Regular cyclic stock counting indicates for distributing supply system
C. Regular cyclic stock counting makes harder to staff to pilfer stock
D. Annual stock counting simplifies recording of physical count with records

29. D Which one of the following statement is true about formulary and non
formulary drugs?
A. Non formulary drugs are used in large amounts
B. Every prescribers should access non formulary drugs
C. No need of management to limit the number of non formulary drugs
D. Open formulary system allows introduction of non formulary drugs

30. B Which one of the following statements is TRUE about the rational of small
scale compounding of pharmaceuticals ?
A. Many patients are allergic excipients in commercially available products
B. Many patient needs dosage forms that are commercially available
C. Many patients need drug strength that are commercially available
D. Adults medications must be prepared as gum drops and lollipops

31. C Which one of the following is the advantage having essential drugs list for a
health facilities?
A. Increase number of stock items in the store
B. Increase the cost of stocks items prescribed
C. Increase patient adherences
D. All

32. D A pharmacy technician has reconstituted single dose vials of antibiotics using
closed system transfer methods. The risk involved in such simple admixture
compound process is classified as:

A. Medium risk compounding


B. High risk compounding
C. Low risk compounding
D. Non risk compounding

33. C Patient is 6 years old and the physician prescribed Amoxycilline 250 mg
/5 ml TID for 7 days, but you have Amoxycilline 125 mg/5 ml then .How
many you dispense to the patient?
A. 150 mm /5ml
B. 210 ml /5 ml
C. 10 ml/210 ml
D. 10 ml/200 ml

34. NO ANSWER which one of the following are not correctly matched /
A. Clean sterilization (Ethanol)
B. Radiation sterilization (Gama)
C. Steam sterilization ( Autoclave)
D. Dry heat sterilization (Oven)
E. all

35. C Amanuael Hospitals consumption of Phenobarbitone 30 mg for last 6


months is 600000 tablets .The pharmacy 61 days stock out then what is
average monthly consumption :-
A. 15,000
B. 1500
C. 150,000
D. 15,00000
36. A Which preparation has high concentration of Sugar?

A. syrup
B. Elixir
C. Sprit
D. all

37. B Identify the non hormonal contraceptive methods

A. COC
B. IUCD
C. Levegestron only
D. none

38. A Which one study about dosage form/

A. pharmaceutics
B. pharmacology
C. physical pharmacy
D. none

39. B The continue process of drug receiving, storing and stock control.....

A. Procurement
B. Distribution
C. Selection
D. none

40. A Which drug need to store in refrigerator?

A. Insulin
B. Diclofenac
C. Amitryptiline
D. none

41. A Which one of the following is homogenous phase?

A. solution
B. suspension
C. ointment
D. creams

42. C semisolid preparation which contain more powder


A. Ointment
B. cream
C. paste
D. none

43. B A suppository which is inserted to the vaginal is known as :-

A. Rectal suppository
B. Pessaries
C. enemas
D. all

44. B vagina agent preparation :-

A. Enemas
B. Douches
C. Pessaries
D. none

45. D False about o/w emulsion

A. External phase is water


B. Internal phase is oil
C. can conduct electricity
D. Greasy by nature

46. A True about Pharmaceutical sprit ,EXCEPT

A. sweetening agent
B. Aromatic water
C. Contain alcohol and volatile oil
D. pharmaceutical aid solution

47. D Which is the rule of DTC in hospital?

A. Selection of drugs
B. Disposing of drugs
C. Editing hospital formulary
D. All
48. C Patient is 6 years old and the physician prescribed Amoxycilline 250 mg
/5 ml TID for 7 days, but you have Amoxycilline 125 mg/5 ml then .How
many you dispense to the patient?
A. 150 mm /5ml
B. 210 ml /5 ml
C. 10 ml/210 ml
D. 10 ml/200 ml

49. NO ANSWER which one of the following are not correctly matched /
A. Clean sterilization (Ethanol)
B. Radiation sterilization (Gama)
C. Steam sterilization ( Autoclave)
D. Dry heat sterilization (Oven)
E. all

50. C Amanuael Hospitals consumption of Phenobarbitone 30 mg for last 6


months is 600000 tablets .The pharmacy 61 days stock out then what is
average monthly consumption :-
A. 15,000
B. 1500
C. 150,000
D. 15,00000

51. A Which preparation has high concentration of Sugar?

A. syrup
B. Elixir
C. Sprit
D. all

52. B Identify the non hormonal contraceptive methods

A. Combined oral contraceptive


B. IUCD
C. Levegestron only
D. none

53. A Which one study about dosage form/


A. pharmaceutics
B. pharmacology
C. physical pharmacy
D. none

54. B The continue process of drug reciving, storing and stock control.....

A. Procurement
B. Distribution
C. Selection
D. none

55. A Which drug need to store in refrigerator?

A. Insulin
B. Diclofenac
C. Amitryptiline
D. none

56. A Which one of the following is homogenous phase?

A. solution
B. suspension
C. ointment
D. creams

57. C semisolid preparation which contain more powder

A. Ointment
B. cream
C. paste
D. none

58. B A suppository which is inserted to the vaginal is known as :-

A. Rectal suppository
B. Pessaries
C. enemas
D. all

59. B vagina agent preparation :-

A. Enemas
B. Douches
C. pessaries
D. none

60. D False about o/w emulsion

A. External phase is water


B. Internal phase is oil
C. can conduct electricity
D. Greasy by nature

61. A True about Pharmaceutical sprit ,EXCEPT

A. sweetening agent
B. Aromatic water
C. contain alcohol and volatile oil
D. pharmaceutical aid solution

62. D Which is the rule of DTC in hospital?

A. Selection of drugs
B. Disposing of drugs
C. Editing hospital formulary
D. all

63. D Rx: - Amoxicillin 250mg/5ml suspension tid for 7 days was prescribed for a
patient. On hand you will have 125mg/5ml suspension. How many ml you
dispense?
A. 5ml, 200ml
B. 5ml, 210ml
C. 10ml, 200ml
D. 10ml, 210ml
64. C Which one of the following is psychotropic controlled drug?
A. Pethidine
B. Tramadol
C. Diazepam
D. Morphine
65. B Which one of the following is not controlled drug?
A. Pethidine
B. Amitryptiline
C. Morphine
D. Diazepam
66. D Which one of the following is the same properties about traditional drug and
modern drug
A. More people choose this medication
B. Approves scientifically
C. Cost saving medication
D. Treats patients
67. B Rx:- Co-trimoxazole 960mg Qod for 2 months. On hand tou will have 480mg
Co-trimoxazole. So, from many tablets you disponse for 2 months.
A. 120 tablets of 480mg Co-trimaxazole
B. 60 tablets of 480mg Co-trimaxazole
C. 90 tablets of 480mg Co-trimaxazole
D. 60 tablets of 960mg Co-trimaxazole
68. B Rx:- Antacid suspension 10ml tid for 1 month. How many bottles you dispense
for 1 month? On hand you will have antacid suspensions which contain 200ml.
A. 4 bottles
B. 5 bottles
C. 6 bottles
D. 7 bottles
69. B A suppository which is inserted to the vaginal is known as
A. Rectal supposition
B. Pessaries
C. Bolus
D. Enemas
70. B Vaginal agent solution preparation
A. Enemas
B. Douchase
C. Pessaries
D. None
71. D False about o/w emulsion
A. External phase is water
B. Can conduct electric current
C. Internal phase is oil
D. Greasy by nature
72. A True about pharmaceutical spirit except
A. Sweetening agent
B. Contain Alcohol and Volatile oil
C. Aromatic water
D. Pharmaceutical aid solution
73. D What is the role of drug and therapeutic committee in hospital
A. Selection of drug
B. Editing of hospital formulary
C. Disposing of expire drug
D. All
74. A Which one of the following drug has disulfirum like action?
A. Metronidazole
B. Chloramphenicol
C. Amoxicillin
D. Tetracycline
75. A Which preparation has high concentration of sugar
A. Syrup
B. Elixir
C. Spirit
D. All
76. C Identity the non-hormonal contraceptive methods
A. Combined oral contraceptive
B. Levenorgestrol only
C. IUCD
D. None
77. A Which one study about dosage forms
A. Pharmaceutics
B. Pharmacology
C. physical pharmacy
D. None
78. A The continuous process of drug receiving, storing and stock controlling
A. Distribution
B. Procurement
C. Selection
D. None
79. A Which drug need to store in refrigerator
A. Insulin
B. Diclofenac
C. Amytriptylline
D. None
80. D Which one is a homogenizes phase
A. Suspension
B. Ointment
C. Cream
D. None
81. D One is not traditional medicine
A. Acunpacture
B. Ayurveda
C. Homopathy
D. None
82. D Semi solid preparation which contain more powder
A. Ointment
B. Cream
C. Jelly
D. None
MATCHING

INSTRUCTION FOR MATCHING

COLUMN “ A” COLUMN “B”

1. I Available stock at any point in time A. active ingredient


B. Incipient
2. K Date that the first step of manufacture is
C. IFRR
performed
D. stability
3. D Capacity of drug product to maintain its
E. Cool
indentity,strength, quality and purity
F. Master formula
throughout its shelf life
G. Shelf life
4. A substance with pharmacological effect H. Cold
5. B Any component present in the intermediate I. Stock on hand
or API that is not the desired entity J. Expire date
6. O Concentration of the drug substance K. Manufactured date
L. Impurity
7. F document specifying ingredients with their
M. Stock card
quantity for compounding
N. Safety stock
8. J date at which them manufacture no longer
O. Strength
guarantee efficacy ,safety and stability drug
P. RRF
product
Q. Dose
9. R 15-25 oc R. Room temperature
10. H 2-8 oc S. Bin card
11. E 8-15 oc T. purity

12. S Kept with items


13. P Report and requests from dispensing units
14. Q Amount of drug taken /administer once
15. L Ingredients in formulation other than drug
substance
MATCHING

INSTRUCTION FOR MATCHING

COLUMN “ A” COLUMN “B”

16. 20 Batch Number


1. OD
17. 19 Flocculated suspension
2. Both eyes
18. ? DTC 3. Paste

19. 17 Titration 4. B-Lactam


5. Ketoconazole
20. 16 Amber Glass
6. After meal
21. 15 Douche 7. A.U

22. 14 O/W emulsion 8. A.D


9. A.S
23. 13 Acupuncture
10. Sweetening agent
24. 12 Stetscope 11. Cleaning object

25. 11 Disinfectant 12. Undisposable object


13. Traditional medicine
26. 10 Sucrose
14. Emulsion that conduct electricity
27. 9 Left ear 15. Vaginal agent preparation

28. 8 Right ear 16. To protect the product from light


17. To make compounding
29. 7 Both ears
18. Dispersed materials
30. 6 PC 19. highly sedimented suspension

31. 21 AC 20. rename and known products


21. Before meal
32. 5 Antifungal

33. 4 Ampicillin
34. 3 Highly powder

35. 2 OU

36. 1 Right eye

MATCHING

INSTRUCTION FOR MATCHING

COLUMN “ A” COLUMN “B”

1. K Universal Anti-Dote A. Make odorant


B. Amoxycilline
2. J Atropine
C. Niclosamide
3. ? USP D. Amitryptiline

4. I Anti flatulence E. Cotrimoxazole


F. Non opioid analgesic
5. H Ketoconazole
G. Antipyretics
6. G Paracetamol H. Antifungal

7. E TS I. Gas expel
J. Antidote for Malation
8. D Tricyclic Antidepressant
K. Activate Charcoal
9. C Anthelmintic
10. B Clavulanic acid

11. A Flavoring

MATCHING

INSTRUCTION FOR MATCHING

COLUMN “ A” COLUMN “B”


1. M Trituration A. Right eye
B. Prevent contamination
2. L Amber glass
C. Left eye
3. K Batch number D. Sweetening agent

4. J Flocculated suspension E. Undisposabel products


F. Traditional medicine
5. ? DTC
G. Alcohol and Aromatic water
6. I Douches H. Emulsion that conduct electricity
7. H O/W emulsions I. Vaginal agent preparation
J. High sediment preparation
8. G Sprits
K. Rename and known the
9. F Acupuncture products
10. E Stethoscope L. To protect the product from light
M. To make compounding
11. B Preservative
N. Dispersed material system
12. C OL O. Remove microbes
13. O Disinfectant P. After meal
Q. Annusol
14. R Vaginal suppositories
R. Pessaries
15. A OD S. Transmitted by oro- fecal route
16. D Sucrose T. Caused by E.A histolotica
U. Blood thinner
17. Q Rectal suppositories
V. Antiprotozoa
18. Y Enema W. Formation of blood clot inside
19. N Suspension the Blood vessels
X. Uncontrolled bleeding
20. P PC
Y. Cleansing for rectal
21. S Gardiasis Z. Cotrimoxazole
22. T Ameobiasis

23. U Warfarine

24. V Metronidazole

25. W Thrombosis

26. X Blood disorders

27. Z Pneumonia
MATCHING

INSTRUCTION FOR MATCHING

COLUMN “ A” COLUMN “B”

28. F B-Blocker A. Ceftraxone


B. Captopril
29. L NSAID
C. Atropa Belladonna
30. M Antihistamine D. Hard paraffin

31. B ACEIs E. Frusamide


F. Propranolol
32. N First generation cephalosporin’s
G. Ketamine
33. H Antifungal H. Griseofulvine

34. H Antifungal drugs safe for children I. Metronidazole


J. Mebendazole
35. K Osmotic diuretic
K. Mannitole
36. E Loop diuretic L. Piroxicame

37. O Viscosity enhancers M. Chlorphenramine


N. Cephalexine
38. J Antihelemntic
O. Methylcellulose
39. G Anaesthetic drugs P. Cinchona Bark

40. D Ointment base Q. Opoide drugs


41. C Leaf which dilate pupil R. United sate of pharmacopeia
S. Antiflatulence
42. P Malaria
T. Antipyretic and analgesic
43. Q Codeine U. ORS

44. R USP V. Hydralazine

45. S Activate charcoal

46. UCommon hospital drug pharmacopia

47. T Paracetamole

MATCHING

INSTRUCTION FOR MATCHING

COLUMN “ A” COLUMN “B”

1. L Phase inversion A. Formaldehyde


B. Quality control assurances
2. M Chlorpromazine
C. Flammable
3. N Blister /strip packaging D. Leaker test

4. R Type II DM E. Rapid onset fraction


F. Body language
5. Q Not traditional medicine
G. Lead time
6. P Sweetening agent H. Pyrogen free

7. J Paste I. Body affected by the drug


J. Ointment which have high
8. W Phynitoyine
powder
9. K Pharmacist K. Drug dispensing

10. E Irrigation fluids L. Emulsion


M. Indication for schizophrenia
11. V Clonazepam
12. F Non verbal communication N. For tablet
O. Pyrogen free
13. G Time from order to receive
P. Sucrose /Saccharin
14. D To cheek leak of Ampoule Q. Implantation

15. O Parentral preparation R. Metformin


S. Lead time
16. B Principle of GMP
T. Filtration sterilization
17. C Label for dangerous products U. Phenytoin

18. A Used to sterilize 500 m V. Treat epilepsy

19. T Used to sterilize heat sensitive


products

MATCHING

INSTRUCTION FOR MATCHING

COLUMN “ A” COLUMN “B”

1. L Anaphylactic shock A. Amoxacilline + Clavulanic


acid
2. G Over the counter
B. Paracetamol antidote
3. J Opportunistic infection C. Analgesics & Antipyretics

4. A Augumentin D. Drop
E. Room temperature
5. C Paracetamol
F. To treat Parkinsonism
6. H Metronidazole disease

7. E 15oc – 25oc G. Dextromethorphan


H. Disulfiram like reaction
8. B N-acetylcysteine
I. Aerosol
9. N Tablespoonful
J. Herpes zoster
10. R Gown K. Every day
L. Adrenaline
11. Q Vaginal suppository
M. Antidote for Malathion
12. S Thalidomide N. 15 ml

13. P Stat O. Liver inflammation


P. At once
14. O Hepatitis
Q. Pessaries
15. T Affect bioavailability R. Personal protection

16. U NSAID S. Teratogenic


T. First pass effect
17. I Pressurized
U. Indomethacin
18. V Methyl dopa V. Safe for pregnancy

19. W Codeine W. Opioid drugs


X. Cool temperature
20. E Chelating agent
Y. Diazepam
21. D NNRT Z. – 15oc to 0oc

22. B Deep freeze EDTA , Tablet , NEV

23. C Binder

24. A Anticonvulsant

MATCHING

Column A Column B
---------1. L Antispasmodic drugs A. Drop
B. Azithromycin
---------2. T ACE inhibitor drugs
C. Four times a day
---------3. J An aesthetic agent D. Zidovudine
---------4. I A diuretic drugs E. Start
F. When required
-------- 5. S An antidepressant drug
G. Immediately at once
---------6. U An antiviral drug H. Every other day
---------7. P Drug used for giardiasis I. Furosemide
J. Ketamine
---------8. N An anthelmintic drug
K. Chlordiazepoxide
---------9. Q An antifungal drug L. Hyoscine
--------10. M An antihistamine drug M. Chlorpheniramine
N. Mebendazole
--------11. D AZT
O. Digoxin
-------- 12. A gtt P. Metronidazole
-------- 13. F Prn Q. Ketoconazole
R. Ciprofloxacin
--------14. H QOD
S. Amitriptyline
--------15. G Stat T. Captopril
U. Acyclovir

Exercise – 5
Answer the following questions by choosing the appropriate
answer from the given alternatives

1.C Which one of the following preparation require emulgent

A.Suspension B.Solution C.Emulsion D.Paste E.None

2.E A suppository which is inserted to the vagina is knoun as

A.Enema B.Douch C.Rectal suppository D.All E.None

3.C Rx cotrimoxazole 960mg QOD for three months,but on hand you have 480mg
cotrimoxazole so how many tablets you dispense for three months?

A.60 tablets of 480mg cotrimoxazole for three months

B.120 tablets of 480mg cotrimoxazole for three months

C.90 tablets of 480mg cotrimoxazole for three months


D.45 tablets of 960mg cotrimoxazole for three months

4.B Which one of the following is not controlled drugs?

A.Pethidine B.Amitryptline C.Morphine D.Diazepam

5.B Rx Ampicillin 250mg/5ml suspension QID for 7 days was prescriped for the
patient,but on hand you have 125mg/5ml suspension so how many ml you dispense?

A.5ml,240ml B.10ml,280ml

C.10ml,260ml D.20ml,280ml

6.B Which one of the following is the same properties of traditional drug and modern
drug

A.Save cost for medication B.Treat patient

C.More people choose this medication D.All

7.B One is diferrent from others

A.Tablet B.Cream c.Granule D.Powder

8.B Which stock controlling mechanism used to issue drugs that have the same expiry
date

A.FEFO B.FIFO C.LIFO D.All

9.D The role of drug and therapeutic commite

A.Selection of an appropriate drug B.Editing hospital formulary

C.Preparing national drug policy D.All

10.C An important expient added on tablet formulation

A.Wetting agent B.Emulgent C.Binder D.Suspending agent

11.D Which one of the following is falseabout O/W emulsion

A.External phase is water B.InternaI phase is oil

C.It can conduct electricity D.It is greasy by nature


12 .A Except one all are true about pharmaceutical spirit

A.It is sweetening agent B.It is aromatic agent

C.It contains alchol and volatile oil D.Has carminative effect

13.C The drug of choice to treat all form of epilepsy

A.Diazepam B.Ethosuximide C.Pheyntoin D.Promethazine

14.C An health profesion who is drug expert and can dispense drug

A.Medical practitioner B.Physician C.Pharmacist D.Dentist

15.B Identify the main part of the prescription

A.Superscription B.Inscription C.Subscription D.Signatura

16.D Identify the hormonal contraceptive method

A.Pills B.IUCD C.Levegestrone only D.A&C

17.B The drug of choice to treat herpes zoster

A.Methotroxate B.Acyclovir C.Zidovudin D.Amantadine

18.A Which one of the following is not true

A.Amoxacillin is OTC drug

B.Disinfectants are chemicals which are applied on non living things

C.Diazepam is sedative and hypnotic drug

D.Antiseptics are chemicals which are applied on living things

19.B Rx Fortified procaine peniciline 840,000IU IM BID for 7days

How many vial will you dispense to the patient

A.4 vial B.2.94 vial C.3vial D.5vial

20.C Select heterogeneous preparation


A.Large volume parentral B.benzathine penicillin

C.Diclofenac injection D.None

21.B Beta bloker drug used to treat glaucoma

A.Esmolol B.Timolol C.Propranolol D.Atenolol

Appropirately match the correct answer from column B for column A

A B

1.D Anaphylactic shock A.Kidney failure

2.O nocte B.Peppermint spirit

3.Teratogenesis C.Treat CHF

4.G Less/has no anti inflammatory D.Adrenaline

Effect E.Pessary

5.M Codein F.Co-trimoxazole

6.B Carminative G.Paracetamole

7.I Non verbal communication H.N-Acetyl cestin

8.C Digoxin I.Gesture

9.Sterilized preparation J.Disurfirum like action

10.L Coarthum K.Parentral preparation

11.Need drinking of more water L.Treat malaria

12.H Paracetamol toxicity antidote M.Opoid drug

13.J Metrondazole N.Orgon deformity

14.Nephropathy O.At night

15.E Vaginal suppository P.Diclofenac


KEEP CALM & GOOD LUCK FOR YOUR EXAM

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