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References of Impact of nanoparticles on amyloid β-induced Alzheimer's disease, tuberculosis, leprosy and cancer: a systematic review
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101 Amyloid Precursor Protein Processing and 1,179
Highly Cited Papers 19 Alzheimer's Disease Citations
Review Article 59
O'Brien, RJ and Wong, PC 149
Early Access 1 References
2011 | ANNUAL REVIEW OF NEUROSCIENCE, VOL 34 34 ,
Open Access 81
pp.185-204
Associated Data 2
View PDF Alzheimer's disease (AD), the leading cause of dementia 29
worldwide, is characterized by the accumulation of the beta-
amyloid peptide (A beta) within the brain
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12/30/23, 6:23 AM References of Impact of nanoparticles on amyloid β-induced Alzheimer's disease, tuberculosis, leprosy and cancer: a systematic review – 169 – Web of Science Core Collection
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102 VIP-grafted sterically stabilized phospholipid 49
nanomicellar 17-allylamino-17-demethoxy Citations
2018 11
geldanamycin: A novel targeted nanomedicine
See all > for breast cancer
24
References
Önyüksel, H; Mohanty, PS and Rubinstein, I
Document Types Jan 5 2009 | INTERNATIONAL JOURNAL OF PHARMACEUTICS
365 (1-2) , pp.157-161
Cited Reference 169
17-Allylamino-17-demethoxy geldanamycin (17-AAC), an
Journal Article 144
inhibitor of heat shock protein 90 (Hsp90) function, is being
Article 139
developed as antitumor drug in patients
... Show
with breast
more cancer.
Research Support, Non-U.S. Gov't 65
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103 [Not available] 10
Citations
Affiliations Organization, WH.
2020 | Global tuberculosis report, 2020 0
WHO, Geneva, Switzerland References
Publication Titles
Search my library catalogue
Languages 29
Countries/Regions
104 The C-terminal extension of Mycobacterium 12
tuberculosis Hsp16.3 regulates its Citations
Research Areas oligomerization, subunit exchange dynamics and
chaperone function
62
References
Open Access Panda, AK; Chakraborty, A; (...); Biswas, A
Jan 2017 | FEBS JOURNAL 284 (2) , pp.277-300
Filter by Marked List
Mycobacterium tuberculosis is a human pathogen that secretes
a major immunodominant antigen, namely Hsp16.3,
Funding Agencies throughout the course of infection. Hsp16.3
... Show
belongs
more to the
Conference Titles
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105 Nano based drug delivery systems: recent 2,828
developments and future prospects Citations
Book Series Titles
Patra, JK; Das, G; (...); Shin, HS 260
References
Sep 19 2018 | JOURNAL OF NANOBIOTECHNOLOGY 16
Editors
Nanomedicine and nano delivery systems are a relatively new
Editorial Notices but rapidly developing science where materials in the
nanoscale range are employed to serve
... as
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means
moreof diagnostic
Sustainable Development Goals

Free Full Text from Publisher
106 Hsp90-targeted miRNA-liposomal formulation for 23 29

systemic antitumor effect Citations
Pore, SK; Choudhary, A; (...); Banerjee, R

37
Sep 2013 | BIOMATERIALS 34 (28) , pp.6804-6817 References
Chaperone protein Hsp90 maintains functional integrity and

maturation of a large number of cellular proteins including
transcription factors, kinases, etc. It is...often
Showover-expressed
more in
Full Text at Publisher

107 Hyaluronic acid-decorated poly(lactic-co-glycolic 39

acid) nanoparticles for combined delivery of Citations
docetaxel and tanespimycin
44
Pradhan, R; Ramasamy, T; (...); Kim, JO References
Jun 5 2015 | CARBOHYDRATE POLYMERS 123 , pp.313-323
Multiple-drug combination therapy is becoming more common

in the treatment of advanced cancers because this approach
can decrease side effects and delay or...prevent
Show more
drug resistance.
Full Text at Publisher more_horiz Related records
108 Quercetin-loaded selenium nanoparticles inhibit 23

amyloid-β aggregation and exhibit antioxidant Citations
activity
47
Qi, YJ; Yi, PJ; (...); Zhang, Y References
29
Oct 5 2020 |
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND
ENGINEERING ASPECTS
602
Related records
Abnormal aggregation of amyloid-beta (A beta) particles and
oxidative stress are pathological hallmarks of Alzheimer's
disease (AD). Quercetin (Que), a flavonoid
... Show
antioxidant,
more has
View full text

more_horiz
109 Recent advancements of nanoparticles 41
application in cancer and neurodegenerative Citations
disorders: At a glance
328
Rahman, MM; Islam, MR; (...); Wilairatana, P References
Sep 2022 | BIOMEDICINE & PHARMACOTHERAPY 153
Nanoscale engineering is one of the innovative approaches to

heal multitudes of ailments, such as varieties of malignancies,
neurological problems, and infectious...illnesses.
Show more
Therapeutics

110 Modeling of the Inhibitory Effect of Nanoparticles 19

on Amyloid β Fibrillation Citations
Ramesh, NK; Sudhakar, S and Mani, E 62 29

References
Apr 3 2018 | LANGMUIR 34 (13) , pp.4004-4012
Experiments have shown that charged nano particles (NP)

inhibit, partially or completely, the aggregation of A beta
protein monomers into fibrils. The equilibrium
... Show more
fibril content is

111 Alzheimer's Disease: Critical Notes on the History 55

of a Medical Concept Citations
Ramirez-Bermudez, J 22
References
Nov 2012 | ARCHIVES OF MEDICAL RESEARCH 43 (8) , pp.595-
599
It is generally accepted that Alois Alzheimer, the German

neuropathologist and clinician, discovered the disease that
carries his name, after the clinicopathological
... Show study
more of a 51-

112 Structure-based design of 7-carbamate analogs 43

of geldanamycin Citations
Rastelli, G; Tian, ZQ; (...); Liu, YQ 19

Nov 15 2005 | References
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 15 (22) ,
pp.5016-5021
The 7-carbamate groups of geldanamycin and its 17-(2-

dimethylaminoethyl)amino-17-demethoxy derivative (17-
DMAG) bind the N-terminal domain of...Hsp90
Showbymore
establishing a 29

113 Dual mode of cancer cell destruction for 31

pancreatic cancer therapy using Hsp90 inhibitor Citations
loaded polymeric nano magnetic formulation
45
Rochani, AK; Balasubramanian, S; (...); Kumar, DS References
Sep 10 2016 |
INTERNATIONAL JOURNAL OF PHARMACEUTICS 511 (1) ,
pp.648-658
Heat Shock Protein 90 (Hsp90) has been extensively explored as

a potential drug target for cancer therapies. 17-N-allylamino-
17-demethoxygeldanamycin (17AAG)...was Show
the first
more Hsp90
Full Text at Publisher more_horiz Related records
114 Structural basis for inhibition of the Hsp90 859

molecular chaperone by the antitumor Citations
antibiotics radicicol and geldanamycin
39
Roe, SM; Prodromou, C; (...); Pearl, LH References
Jan 28 1999 | JOURNAL OF MEDICINAL CHEMISTRY 42 (2) ,

pp.260-266
The cellular activity of several regulatory and signal

transduction proteins, which depend on the Hsp90 molecular
chaperone for folding, is markedly decreased
... Showbymore
geldanamycin
29
Full Text at Publisher View Associated Data more_horiz Related records
115 Targeted nanoparticles for drug delivery through 278

the blood-brain barrier for Alzheimer's disease Citations
Roney, C; Kulkarni, P; (...); Aminabhavi, TM 89

Nov 28 2005 | JOURNAL OF CONTROLLED RELEASE 108 (2-3) ,
References
pp.193-214
Alzheimer's disease (AD) is the most common cause of

dementia among the elderly, affecting 5% of Americans over
age 65, and 20% over age 80. An excess
... ofShow
senile
more
plaques (beta-

116 Protein glycosylation in the endoplasmic 63

reticulum and the Golgi apparatus and cell type Citations
specificity of cell surface glycoconjugate
expression: Analysis by the protein A-gold and
129
References
lectin-gold techniques
Roth, J
Jul 1996 | HISTOCHEMISTRY AND CELL BIOLOGY 106 (1) ,
pp.79-92
High resolution immunolabeling applying the protein A-gold

technique and carbohydrate cytochemistry using lectin-gold
labeling on Lowicryl K4M and thawed-frozen
... Showthin
more
sections are 29
Full Text at Publisher Full Text at Publisher

117 Neurotherapeutic applications of nanoparticles 160

in Alzheimer's disease Citations
Sahni, JK; Doggui, S; (...); Ramassamy, C 345

References
Jun 10 2011 | JOURNAL OF CONTROLLED RELEASE 152 (2) ,
pp.208-231
A rapid increase in incidence of neurodegenerative disorders

has been observed with the aging of the population.
Alzheimer's disease (AD) is the most common
... Show more

118 Open-label, dose-escalation, safety, 23

pharmacokinetic, and pharmacodynamic study Citations
of intravenously administered CNF1010 (17-
(allylamino)-17-demethoxygeldanamycin [17-
43
References
AAG]) in patients with solid tumors
Saif, MW; Erlichman, C; (...); Von Hoff, D

May 2013 | CANCER CHEMOTHERAPY AND PHARMACOLOGY
71 (5) , pp.1345-1355
17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) is a
benzoquinone ansamycin that binds to and inhibits the Hsp90
family of molecular chaperones leading
... to
Show
the more
proteasomal 29

119 Controlling Amyloid-β Peptide(1-42) 40

Oligomerization and Toxicity by Fluorinated Citations
Nanoparticles
65
Saraiva, AM; Cardoso, I; (...); Brezesinski, G References
Sep 3 2010 | CHEMBIOCHEM 11 (13) , pp.1905-1913
The amyloid-p peptide (A beta) is a major fibrillar component of

neuritic plaques in Alzheimer's disease brains and is related to
the pathogenesis of the disease. Soluble
... Show
oligomers
morethat

120 Formulation and in vitro efficacy of liposomes 21

containing the Hsp90 inhibitor 6BrCaQ in Citations
prostate cancer cells
40
Sauvage, F; Franzè, S; (...); Vergnaud-Gauduchon, J References
Feb 29 2016 |
INTERNATIONAL JOURNAL OF PHARMACEUTICS 499 (1-2) ,

pp.101-109
6BrCaQ is a promising anti-cancer agent derived from

novobiocin, which has been shown to inhibit Hsp90. 6BrCaQ
was loaded into nanometer-scaled phospholipid
... Show more
vesicles

29
121 Nanomaterials to avoid and destroy protein 24

aggregates Citations
Sauvage, F; Schymkowitz, J; (...); De Smedt, SC 123

References
Apr 2020 | NANO TODAY 31
Aggregation of proteins is involved in many disorders. Besides

amyloid fibrils, which mostly form in the brain, other kind of
protein aggregates can lead, for example,
... Show
to clots
morein the blood
Free Published Article From Repository View full text

122 Formulation and in vitro evaluation of 17- 26

allyamino-17-demethoxygeldanamycin (17-AAG) Citations
loaded polymeric mixed micelles for
glioblastoma multiforme
40
References
Saxena, V and Hussain, MD
Dec 1 2013 | COLLOIDS AND SURFACES B-BIOINTERFACES 112
, pp.350-355
Glioblastoma multiforme (GEM) is the most common and

aggressive malignant primary brain tumor in human. 17-
Allylainino-17-demethoxy geldanamycin
... Show
(17-AAG)
moreis all

29
123 Folate receptor targeted 17-allylamino-17- 47
demethoxygeldanamycin (17-AAG) loaded Citations
polymeric nanoparticles for breast cancer 44

Saxena, V; Naguib, Y and Hussain, MD References
Jun 1 2012 | COLLOIDS AND SURFACES B-BIOINTERFACES 94 ,
pp.274-280
Low water solubility and hepatotoxicity limited the clinical use

of 17-allylamino-17-demethoxy geldanamycin (17-AAG), an
inhibitor of heat shock protein 90 (HSP90).
... Show
Folate
moretargeted

124 Mechanisms of action of photodynamic therapy 380

with verteporfin for the treatment of age-related Citations
macular degeneration
99
Schmidt-Erfurth, U and Hasan, T References
Nov-dec 2000 | SURVEY OF OPHTHALMOLOGY 45 (3) , pp.195-

214
Age-related macular degeneration, especially the neovascular

form of the disease, is the loading cause of blindness in elderly
people in developed countries. Thermal... Show
photocoagulation
more is

125 Emerging Technologies to Target Drug Delivery to 8

the Skin - the Role of Crystals and Carrier-Based Citations
Systems in the Case Study of Dapsone
140 29
Schneider-Rauber, G; Argenta, DF and Caon, T References
Nov 9 2020 | PHARMACEUTICAL RESEARCH 37 (12)
Dapsone (DAP) is a long-established molecule that remains a

promising therapeutic agent for various diseases mainly
because it combines antimicrobial and... anti-inflammatory
Show more
more_horiz
Related records
126 Antibiotic radicicol binds to the N-terminal 342

domain of Hsp90 and shares important biologic Citations
activities with geldanamycin
38
Schulte, TW; Akinaga, S; (...); Neckers, LM References
Jun 1998 | CELL STRESS & CHAPERONES 3 (2) , pp.100-108
The molecular chaperone Hsp90 plays an essential role in the

folding and function of important cellular proteins including
steroid hormone receptors, protein kinases
... Show
andmore
proteins
Free Published Article From Repository Full Text at Publisher
127 Alzheimer's disease: Genes, proteins, and therapy 4,971

Citations
Selkoe, DJ
Apr 2001 | PHYSIOLOGICAL REVIEWS 81 (2) , pp.741-766 216
References
Rapid progress in deciphering the biological mechanism of
29
Alzheimer's disease (AD) has arisen from the application of
molecular and cell biology to this complex
... Show
disorder
moreof the

128 Toxicity of metal and metal oxide nanoparticles: 215

a review Citations
Sengul, AB and Asmatulu, E 146

Sep 2020 | Jun 2020 (Early Access) | References
ENVIRONMENTAL CHEMISTRY LETTERS 18 (5) , pp.1659-1683
Nanotechnology has recently found applications in many fields

such as consumer products, medicine and environment.
Nanoparticles display unique properties
... Show
and vary
morewidely

129 Nanoparticles as antimicrobial and antiviral 90

agents: A literature-based perspective study Citations
Sharmin, S; Rahaman, MM; (...); Adeyemi, OS 112

References
Mar 2021 | Mar 2021 (Early Access) | HELIYON 7 (3)
The scientific explorations of nanoparticles for their inherent

therapeutic potencies as antimicrobial and antiviral agents due
to increasing incidences of antibiotic...
resistance
Show more
have gained

29
130 71
Gold Nanocage-Based Dual Responsive "Caged Citations

Metal Chelator" Release System: Noninvasive 60
Remote Control with Near Infrared for Potential References
Treatment of Alzheimer's Disease
Shi, P; Li, M; (...); Qu, XG
Nov 20 2013 | ADVANCED FUNCTIONAL MATERIALS 23 (43) ,
pp.5412-5419
Metal ions have been demonstrated to participate in the

pathology of Alzheimer's disease (AD): amyloid- peptide (A)
aggregation and formation of neurotoxic
... Show
reactive
moreoxygen
more_horiz
Related records
131 A 3-in-1 Polymeric Micelle Nanocontainer for 101

Poorly Water-Soluble Drugs Citations
Shin, HC; Alani, AWG; (...); Kwon, GS 34

References
Jul-aug 2011 | MOLECULAR PHARMACEUTICS 8 (4) , pp.1257-
1265
Poly(ethylene glycol)-block-poly(D,L-lactic acid) (PEG-b-PLA)

micelles have a proven capacity for drug solubilization and
have entered phase III clinical trials as
...a substitute
Show morefor
Free Accepted Article From Repository Full Text at Publisher
29
132 28
Influence of surface coating on the intracellular Citations

behaviour of gold nanoparticles: a fluorescence 49
References
MENU correlation spectroscopy study
Silvestri, A; Di Silvio, D; (...); Moya, SE
Oct 14 2017 | NANOSCALE 9 (38) , pp.14730-14739
In the biomedical applications of nanoparticles (NPs), the

proper choice of surface chemistry is a crucial aspect in their
design. The nature of the coating can...heavily
Showimpact
more the
Free Published Article From Repository Full Text at Publisher
more_horiz
Related records
133 Targeted therapy in chronic diseases using 292

nanomaterial-based drug delivery vehicles Citations
Singh, AP; Biswas, A; (...); Maiti, P 256

Aug 30 2019 | References
SIGNAL TRANSDUCTION AND TARGETED THERAPY 4
The application of nanomedicines is increasing rapidly with the

promise of targeted and efficient drug delivery. Nanomedicines
address the shortcomings of conventional
... Show
therapy,
moreas

134 Organic Nanoparticle-Based Combinatory 22 29

Approaches for Gene Therapy Citations
Singh, BN; Prateeksha; (...); Atanasov, AG

15
Dec 2017 | TRENDS IN BIOTECHNOLOGY 35 (12) , pp.1121-1124 References
Engineered organic nanoparticle (ONP)-mediated co-delivery

of genes and therapeutic agents is emerging as a powerful tool
in the treatment of several genetic and non-genetic disorders.

135 Phytogenic silver, gold, and bimetallic 36

nanoparticles as novel antitubercular agents Citations
Singh, R; Nawale, L; (...); Chopade, BA 36

References
2016 | INTERNATIONAL JOURNAL OF NANOMEDICINE 11
Purpose: Multi- and extensively drug-resistant tuberculosis (TB)

is a global threat to human health. It requires immediate action
to seek new antitubercular compounds ... and
Showdevise
morealternate

136 Biomodal Tumor-Targeted and Redox-Responsive 59

Bi2Se3 Hollow Nanocubes for MSOT/CT Imaging Citations
Guided Synergistic Low-Temperature

57
Photothermal Radiotherapy References
Song, YL; Wang, YL; (...); Li, N
Jul 2019 (Early Access) | ADVANCED HEALTHCARE MATERIALS

29
Hyperthemia (>50 degrees C) induced heating damage of

nearby normal organs and inflammatory diseases are the main
challenges for photothermal therapy...
(PTT)
Show
of cancers.
more To Related records

more_horiz
137 Biological applications of gold nanoparticles 1,394
Citations
Sperling, RA; Rivera gil, P; (...); Parak, WJ
Sep 2008 | CHEMICAL SOCIETY REVIEWS 37 (9) , pp.1896-1908 142
References
This critical review gives a short overview of the widespread
use of gold nanoparticles in biology. We have identified four
classes of applications in which gold ...
nanoparticles
Show morehave been

138 Rapid Dissolution of Amyloid β Fibrils by Silver 17

Nanoplates Citations
Sudhakar, S and Mani, E 50

References
May 28 2019 | LANGMUIR 35 (21) , pp.6962-6970
Plaques of amyloid beta (A beta) protein are associated with

neurodegenerative diseases, and preventing their formation
and dissolution of plaques are essential
... to
Show
the more
development of

29
139 Enhanced Internalization of Macromolecular 8

Drugs into Mycobacterium smegmatis with the Citations
Assistance of Silver Nanoparticles 38
References
Sun, FF; Oh, S; (...); Park, EY
Aug 2017 |
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 27 (8) ,

pp.1483-1490
In this study, silver nanoparticles (AgNPs) were synthesized by

the citrate reduction process and, with the assistance of n-
hydroxysuccinimide and 1-ethyl-3-(3-dimethylaminopropyl)
... Show more
Free Submitted Article From Repository View full text

140 Silver Nanoparticles for the Therapy of 35

Tuberculosis Citations
Tabaran, AF; Matea, CT; (...); Mocan, L 260

References
2020 | INTERNATIONAL JOURNAL OF NANOMEDICINE 15 ,
pp.2231-2258
Rapid emergence of aggressive, multidrug-resistant

Mycobacteria strain represents the main cause of the current
antimycobacterial-drug crisis and status
... Show
of tuberculosis
more (TB) as

141 Gold nanorods together with HSP inhibitor-VER- 94 29

155008 micelles for colon cancer mild- Citations
temperature photothermal therapy
Tang, XC; Tan, LW; (...); Qian, ZY

83
Jul 2018 | ACTA PHARMACEUTICA SINICA B 8 (4) , pp.587-601 References
Enhancing the heat-sensitivity of tumor cells provides an

alternative solution to maintaining the therapeutic outcome of
photothermal therapy (PIT). hi this study,
... Show
we constructed
more a

142 Preparation of nanoparticle albumin bound 3

17AAG (nab-17AAG) suitable for intravenous Citations
administration.
0
Tao, Chunlin; Yu, Chengzhi; (...); Desai, Neil References
96th Annual Meeting of the American-Association-for-Cancer-
Research
Apr 2005 |
Proceedings of the American Association for Cancer Research
Annual Meeting
46 , pp.336
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12/30/23, 6:23 AM References of Impact of nanoparticles on amyloid β-induced Alzheimer's disease, tuberculosis, leprosy and cancer: a systematic review

ystematic review – 169 – Web of Science Core Collection

English expand_more apps Products

169 references mentioned in:

link Copy query link

2022 4 more_horiz Related records

Web of Science Index

Sustainable Development Goals

106 Hsp90-targeted miRNA-liposomal formulation for 23 29

Pore, SK; Choudhary, A; (...); Banerjee, R

Chaperone protein Hsp90 maintains functional integrity and

Full Text at Publisher

107 Hyaluronic acid-decorated poly(lactic-co-glycolic 39

Jun 5 2015 | CARBOHYDRATE POLYMERS 123 , pp.313-323

Multiple-drug combination therapy is becoming more common

Full Text at Publisher more_horiz Related records

108 Quercetin-loaded selenium nanoparticles inhibit 23

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND

View full text

Sep 2022 | BIOMEDICINE & PHARMACOTHERAPY 153

Nanoscale engineering is one of the innovative approaches to

Full Text at Publisher

110 Modeling of the Inhibitory Effect of Nanoparticles 19

Ramesh, NK; Sudhakar, S and Mani, E 62 29

Experiments have shown that charged nano particles (NP)

Full Text at Publisher

111 Alzheimer's Disease: Critical Notes on the History 55

It is generally accepted that Alois Alzheimer, the German

Full Text at Publisher

112 Structure-based design of 7-carbamate analogs 43

Rastelli, G; Tian, ZQ; (...); Liu, YQ 19

The 7-carbamate groups of geldanamycin and its 17-(2-

Full Text at Publisher

113 Dual mode of cancer cell destruction for 31

Heat Shock Protein 90 (Hsp90) has been extensively explored as

Full Text at Publisher more_horiz Related records

114 Structural basis for inhibition of the Hsp90 859

Jan 28 1999 | JOURNAL OF MEDICINAL CHEMISTRY 42 (2) ,

The cellular activity of several regulatory and signal

Full Text at Publisher View Associated Data more_horiz Related records

115 Targeted nanoparticles for drug delivery through 278

Roney, C; Kulkarni, P; (...); Aminabhavi, TM 89

Alzheimer's disease (AD) is the most common cause of

Full Text at Publisher

116 Protein glycosylation in the endoplasmic 63

High resolution immunolabeling applying the protein A-gold

Full Text at Publisher Full Text at Publisher

117 Neurotherapeutic applications of nanoparticles 160

Sahni, JK; Doggui, S; (...); Ramassamy, C 345

A rapid increase in incidence of neurodegenerative disorders

Full Text at Publisher

118 Open-label, dose-escalation, safety, 23

Saif, MW; Erlichman, C; (...); Von Hoff, D

Full Text at Publisher

119 Controlling Amyloid-β Peptide(1-42) 40

Sep 3 2010 | CHEMBIOCHEM 11 (13) , pp.1905-1913

The amyloid-p peptide (A beta) is a major fibrillar component of

Full Text at Publisher

120 Formulation and in vitro efficacy of liposomes 21

INTERNATIONAL JOURNAL OF PHARMACEUTICS 499 (1-2) ,

6BrCaQ is a promising anti-cancer agent derived from

Full Text at Publisher

121 Nanomaterials to avoid and destroy protein 24