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Australian Dental Journal

The official journal of the Australian Dental Association


Australian Dental Journal 2018; 63:(1 Suppl): S11–S18

doi: 10.1111/adj.12586

Contemporary exodontia
PJ Sambrook, AN Goss
Oral & Maxillofacial Surgery Unit, Faculty of Health Sciences, The University of Adelaide, Adelaide, South Australia, Australia.

ABSTRACT
Exodontia is a cardinal skill of all dentists. Patients expect extractions to be skillfully and painlessly accomplished every
time. It’s not necessarily so simple and can be challenging. In this paper we explore contemporary issues of the full pro-
cess of exodontia including diagnosis, technique, complication minimization as well as management of medically com-
promised patients with appropriate post-operative care, including pharmacotherapy.
Keywords: Complications, dentoalveolar surgery, exodontia, medically compromised, pharmacology, ridge preservation.
Abbreviations and acronyms: AF = Atrial fibrilation; GA = General anaesthetic; INR = International normalising ratio; IV = Intra-
venous; LA = Local anaesthesia; MRONJ = Medication related osteonecrosis of the jaws; NICE = National Institute for Health and
Care Excellence; Nm = Newton meters; NOAC = Novel oral anticoagulant agent; NSAIDS = Non steroidal anti inflammatory drugs;
OMS = Oral & Maxillofacial Surgery; ORN = Osteoradionecrosis.
Accepted for publication October 2017.
[Correction added on 18 May 2018 after first online publication: Table 2 has been added.]

advanced periodontal disease or fracture. It is more


INTRODUCTION
difficult in the presence of an insistent patient wanting
an apparently painful tooth extracted when clinical
Exodontia is a cardinal skill of all dentists
and radiographic examination shows an intact tooth.
In this paper, we present contemporary issues related It is mandatory that a proper history and examination
to exodontia. Patients expect extractions to be skill- are undertaken to exclude referred pain from cramped
fully and painlessly accomplished every time. Extrac- masticatory muscles or sinus disease as causes of max-
tions are not necessarily simple and can be illary tooth pain. Both of these are common mistakes.
challenging. Diagnosis, technique, complication mini- Similarly trigeminal neuralgia will do a very good imi-
mization as well as management of medically compro- tation of toothache.1 Dentists should not take out
mised patients with post-operative care, including teeth on the insistence of patients in the absence of a
pharmacotherapy will be presented. clear cut diagnosis. A surgeon who removed a normal
body part because the patient demanded it would jus-
tifiably be sued. Absolutely if the patient returns and
Decision to extract or not
demands another extraction or root filling because the
Any surgical procedure requires careful consideration pain is still there, they mandatorily need to be care-
of the harm and benefits (Table 1). This requires a full fully reevaluated or referred for advice.
diagnostic process of history and examination and Common indications for extraction of normal teeth,
special tests. Pre extraction radiographs will confirm but at a mouth level, include orthodontic extractions
the diagnosis and indicate factors of potential diffi- where there is a tooth size/jaw size discrepancy or as
culty (Figs 1a–1c). Pulpal sensibility and assessment of part of a prosthodontic plan. What contribution to
the periodontium can be invaluable additional pieces mastication does the malposed tooth make? These
of information. extractions require careful workup and a fully
Teeth may be considered for extraction at the level informed consent process to the patient’s or their par-
of the individual tooth, the patient’s mouth or the ent for orthodontic patients. Showing them the study
overall patient’s health. It is a common failing that models will often facilitate the process.
inexperienced dentists only look at the individual There are circumstances where extractions need to
tooth. The decision to extract individual teeth can be be considered as part of the overall management of
straightforward in the presence of gross decay, the patient’s health. Management of oncology patients

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PJ Sambrook and AN Goss

Table 1. Harm benefit analysis for surgical proce- extracted is discarded but the residual alveolus must
dures – Exodontia last the patient for the rest of their life.
The tooth is secured to the jaw by a thin periodon-
Benefit Harm
tal membrane composed of multiple interconnected
Procedure performed collagen fibres inserted into the tooth and bone
Exodontia control pain incomplete procedure
resolves problem dry socket
(Figs 2a and 2b). Teeth, particularly with multiple
damage flared roots are further held within the bony socket
Procedure not performed (Fig. 2c). The traditional method of extracting the
No Extraction saves tooth spreading infection
avoids procedure later complications
tooth requires various forces; gripping, rocking and
avoids complications twisting to be applied to the tooth by means of for-
ceps or elevators. The forces involved are quite large;
gripping – 146Nm (126–167), rocking 200Nm (74–
266) and twisting 20Nm (3–13). Nine point eight
Nm (9.80) is approximately 1 kg.5 Multiple roots and
stronger bone all contribute to the force required. If
too great a force is used then either the tooth or the
alveolus will break. Although breaking the alveolus

(a) (b)

Fig. 1 Preoperative radiographs showing potential difficulty in extrac-


tion. (a) Cemental hyperplasia and condensing osteitis. (b) Enostosis. (c)
Dilacerated roots.

does sometimes involve the extraction of compro- (c)


mised but individually savable teeth for patients
undergoing head and neck radiotherapy or chemother-
apy including intravenous antiresorptive agents. These
will be further discussed later in the paper under the
management of medically compromised patients.

Technique
Once the decision to extract has been made the first
issue is the method of pain control for the procedure.
There are multiple choices, local anaesthesia (LA);
LA + oral sedation; LA + IV sedation in rooms or in
hospital or day stay general anaesthetic (GA). A
harm/benefit analysis needs to be applied to each.
Most commonly local anaesthesia is the technique
employed but this is not without complication.2–4
The objectives of exodontia are clear cut; to remove
the whole tooth whilst preserving the alveolus for Fig. 2 (a) Normal periodontal membrane, dentine and cementum left,
future prosthetics or implants. Again it is all too easy alveolar bone right. (b) True boney ankylosis bridge between the tooth
for the inexperienced dentist and their patient to and bone. This is rare and usually there is a history of dental trauma. (c)
Maxillary molar with divergent palatal and buccal roots. Note the thin
emphasise the removal of the whole tooth at the buccal plate at risk of fracture (see Fig. 9a) and the large close maxillary
expense of the alveolus. Remember the tooth once sinus with risk of oroantral communication (see Fig. 9c).
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Contemporary exodontia

will facilitate removal of the tooth it is at the expense


of the final shape of the alveolus. This has lead to the
development of fine periotomes which are carefully
inserted down the periodontal membrane to split it
and gently expand the socket (Fig. 3). If the tooth is
multirooted then the tooth should be sectioned into
its component parts. Although this may take longer it
conserves the alveolus. Fig. 5 (a) Well formed alveolus with broad keratinised mucosa. (b)
Careful conservation of the alveolus must be consid- Alveolus with deficient buccal plate and high non keratinised mucosa.
ered at the time of extraction. If the buccal plate frac-
tures and comes away with the tooth, as it commonly extraction, will always make subsequent prosthetic
does with maxillary canine and molar extractions, it management easier.
can be replaced. It is best firmly fixed with mini screws So what happens if the tooth breaks or can’t be
and a mucosal flap covers the graft (Fig. 4). Alterna- removed? This should be considered as a failure of
tively a small bone graft can be taken from the lower the decision making process as much as a technique
third molar or maxillary tuberosity area. The mini failure. More experienced surgeons will often start
screws are removed some 3–4 months after the extrac- out an extraction as a surgical procedure, raising a
tion at the time the implant is placed. This primary mucoperiosteal flap and sectioning the tooth. This
replacement is always preferable to secondary grafting gives much greater control, is usually swifter and puts
at the time of later implant placement. the patient through much less pressure. What happens
There are two components to the alveolus, the hard if a root tip fractures? Firstly consider leaving it there
and soft tissues. With the soft tissue it is essentially if it is vital, less than 5 mm and in proximity to a
that there is a wide area of keratinised attached gin- vital structure such as a nerve. If you can, remove it
giva (Figs 5a and 5b) at the alveolar crest with soft through a small boney window thus maintaining alve-
pliable mucosa in the vestibule. Careful attention to olar bone height (Fig. 6).
these simple reconstruction principles, at the time of At the time of the extraction one should also care-
fully consider the residual shape of the alveolus. Are
there bony frenae, flabby tuberosity or bony exostoses
and tori (Figs 7a–7e).
Addressing these is all part of the objective of
exodontia, removing the tooth AND preserving the
alveolus for future prostheses or implant.

Complications
Complications are unforeseen and unexpected adverse
sequelae from a surgical procedure. Thus a patient
who bleeds after an extraction but has a known

Fig. 3 Periotone inserted into the periodontal membrane.

Fig. 6 Root tip being approached via a buccal window to conserve the
Fig. 4 Immediate bone graft to the alveolus placed at time of extraction. alveolus.
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PJ Sambrook and AN Goss

Fig. 7 Surgical indication for corrections of alveolar bone shape. (a) Low set frenum. (b) Thick lingual frenum onto an atrophic ridge. (c) Large flabby
tuberosities. (d) ulcerated genial tubercles. (e) Surgical removal of a torus palatines.

The most common complication of exodontia is


alveolar osteitis or dry socket.6 In this common condi-
tion the blood clot undergoes fibrinolysis and the
bony walls of the socket become exposed (Fig. 9a).
This is a painful but self limiting condition which
resolves in 2–3 weeks. The incidence is 3–5% of
extractions with risk factors being traumatic extrac-
tion, smoking, posterior teeth and mandible more
than maxilla, but it is usually unpredictable.6 If there
are signs and symptoms beyond the alveolus then the
Fig. 8 Gross mandibular atrophy in proximity to a pericoronitic third diagnosis needs to be reviewed as it’s not a ‘dry
molar. An invitation to fracture. socket’ but a spreading infection. Excessive granula-
tion tissue usually is as a result of residual pieces of
bleeding diathesis is not really a complication but a tooth or bone (Fig. 9a and 9b).
failure of planning. Similarly, mandibular fracture Penetration into or loss of tooth roots into the sinus
after an attempt at elevator only extraction of the must always be considered in the extraction of poste-
molar, in an elderly patient, with a grossly atrophic rior maxillary teeth (Fig. 9c). After extraction of such
jaw, is a failure of planning and consent (Fig. 8). If a teeth check carefully that they are complete. Check
mandibular premolar is close to the mental foramen for the presence of an oro-antral communication by
unless care is taken the patient may have residual holding the patient’s nose and getting them to blow,
paresthesia, or worse still, dysesthesia of the lower listen for any passage of air or bubbles. If the tooth is
lip. Hence is it a complication or known risk? intact and the communication small, compress the

Fig. 9 Complications. (a) Traumatic extraction of a maxillary molar. Unreduced fractured buccal plate and alveolar osteitis. (b) Exuberant granulation tis-
sue in response to a residual non viable root fragment. (c) Large chronic oroantral communication. (d) Endodontic accident. Not only root tips can end up
in the maxillary sinus. (e) Displaced molar into the intratemporal fossa.

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Contemporary exodontia

socket and suture closed. Tell the patient not to blow Type 2 but a few Type 1 and some Type 2 are a con-
their nose or create a negative pressure. Discuss fully sequence of failure of insulin production in the pan-
with the patient the reason for this sometimes distress- creas. The condition can be readily characterised by
ing complication. If the communication is large, more knowing how long they have had it, their current
than 4 mm or a piece of tooth is missing, promptly medication, blood glucose levels and HbA1c. In a
refer to an Oral and Maxillofacial Surgeon (OMS). landmark study of a large series of Type 2 diabetics
(Fig. 9c and 9d) A two layer mucoperiosteal flap with on oral hypoglycaemics having extractions, we found
a buccal fat pad graft is useful for large communica- that they had less extraction complications than the
tions. control group. The result showed a much higher inci-
Tooth or root displacement, beyond the alveolus dence from smoking in the control group. Thus most
into the soft tissues, is usually a sign of excessive or well controlled Type 2 diabetics on diet control or
misdirected force, don’t ignore this as the probability oral hypoglycaemics can be treated the same as non
of infection is high. Promptly refer to an OMS for diabetic patients.10 Type 1 and those Type 2 diabetics
imaging to localize the tooth and retrieve it (Fig. 9e). requiring insulin are a different proposition, having
If there is a delay in the patient being seen a short both problems of local healing and the effect of
course of antibiotics is appropriate. change in diet from both local wound pain and fast-
ing are more easily destabilised. Specialist referral for
insulin dependent diabetics requiring extraction
Medically compromised patients
should be considered.
In this fortunate age of increased longevity and better
medical management of chronic disease the interac-
STEROIDS
tion of dental and medical compromises plays an
increasing role. Knowledge of the patient’s current Patients are placed on steroids, particularly pred-
medical conditions including their current medications nisolone, for a wide range of medical conditions and
is essential. Interaction with the patient’s medical the particular indication for your patient must be first
practitioner is important but it must be noted that identified. There has been a major change in that
medical practitioners have minimal exposure to oral more patients are on short pulses of steroids rather
and dental conditions so that aspect is the dental than a continued dose. This reduces the risk of
practitioner’s sphere of expertise. cushingoid changes and adrenal suppression. Thus the
Full discussion of the dental interactions with medi- need to double dose prior to procedure is less. The
cal conditions is beyond the scope of this paper. All consequence of long term steroid on wound healing
dentists should keep up to date with contemporary and osteoporosis must be considered. Is the patient
medical practice beyond their undergraduate educa- also on an antiresorptive drug for osteoporosis?
tion.7 Useful references are Therapeutic Guidelines,
Oral & Dental8 and the others in the series, also the
Antiresorptive drugs
Australian Prescriber monthly series.9 Some specific
current conditions with direct impact include those The introduction of the antiresorptive bisphosphonate
which may affect healing, such as diabetes, steroids, drugs in the late 1990’s were a major advance in the
antiresorptives and head and neck radiotherapy as management of bone diseases such as osteoporosis,
well as those which may result in increased bleeding, Paget’s disease and primary and secondary bone can-
including anticoagulants, antiplatelet and haemato- cer. However, in 2003 the risk of bisphosphonate
logic diathesis. In all these conditions a careful harm/ related osteonecrosis of the jaws was identified.11 This
benefit analysis needs to be performed. is of particular importance to dentists as dental proce-
What is the nature of the underlying medical condi- dures, particularly extractions, are the major factor
tion? What is the problem or particular medicine for? for this painful non healing condition. The manage-
How stable is the condition and what are the local ment of this condition has been discussed in a number
and general consequences of your planned procedure? of publications.12–14 A key finding is that the risk of
Can you minimize the risk of harm? medication related osteonecrosis of the jaws
(MRONJ) relates to bone turnover which can be
assessed by the use of the simple blood test, fasted
DIABETES
serum beta cross laps test.15 Current management is
Diabetes is commonly considered by dentists and presented in Table 2. There are newer antiresorptive
patients as a single condition which will result in drugs which are not bisphosphonate, the most com-
increased infection and poor healing. This view is mon of which is Denosumab which is an antibody
incorrect. Diabetes covers a broad spectrum of condi- which acts directly to cease the action of osteoclasts.
tions, mainly a metabolic consequence of obesity for It has this effect for 6 months after which the
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PJ Sambrook and AN Goss

Table 2. Management of patients who are on antire- underlying medical condition and what are the poten-
sorptive agents and requiring extraction tial consequences of altering their drug regimen? In
the last decade there has been a fundamental philo-
Determine the type of bone disease
• Osteopenia sophic shift away from being concerned about the risk
• Osteoporosis of bleeding to the risk of stopping the anticoagulant
• Paget’s disease medication. Oral bleeding is troublesome but a stroke
• Multiple myeloma
• Metastatic bone cancer is a catastrophe.19
Determine the antiresorptive agent Management of patients on Warfarin is straightfor-
• Type ward, determine the INR and if this is between 2.0
• Dose
• Duration and 4.0 leave the Warfarin dose alone and use local
Arrange fasted serum beta cross laps* haemostatic measures for the extraction site.19 If the
• If above 150pg/ml proceed level is below 2.0 or above 4.5 then the dose is not
• If below 150pg/ml cease drug†
Until level reaches over 150pg/ml therapeutic and needs to be adjusted by the prescrib-
Then extract ing medical practitioner. In our extensive studies on
*Dentist can request this test from a pathology lab. Need to state
patients taking Warfarin we found about one-third of
antiresorptive drug and bone problem e.g. Fosamax for osteoporosis. patients were not in the therapeutic range.20 We also

For oral bisphosphonates the level rises at 25 pg/mL per month. found many continued the use of Warfarin beyond
the recommended time for the management of the
osteoclasts become reactivated.16 Hence management underlying medical condition. The most likely extrac-
is simple, avoid bone invasive dental treatment until tion site to have post operative bleeding was a peri-
the seventh month and prior to further injection. odontally involved maxillary molar.20
Extraction site will heal well and then drug usually In some conditions Warfarin has been replaced by
can be resumed within 2 weeks of the extraction.16 antiplatelet agents including aspirin and clopidogrel.
Patients with bone malignancy on antiresorptive medi- For a patient in the 6 months following placement of
cations and patients with established MRONJ are best a metal coronary stent then stopping clopidogrel,
managed by referral to OMS specialists. there is a fifteen percent chance of death.21 Hence,
leave the antiplatelet agent dose as is and use local
haemostatic methods. More recently there have been
Radiotherapy a range of Novel Oral Anticoagulant Agents (NOAC),
Head and neck cancer patients who have had radio- these have replaced Warfarin for management of
therapy are at risk of osteoradionecrosis (ORN) atrial fibrillation (AF) and certain thrombo-embolic
another non healing bone wound. Prevention is better conditions.22 Local haemostatic measures consist of
than cure so all patients should have their teeth care- careful management of the soft tissue without tearing
fully evaluated before radiotherapy commences. This during the extraction; placement of haemostatic agent
is an example of where the emphasis of treatment such as surgicelâ or gelfoamâ in the socket and sutur-
planning is at the whole body level and not the indi- ing. The practitioner performing the procedure must
vidual tooth. If a patient who has had the mandible carefully explain the procedures involved to the
therapeutically irradiated then the correct approach is patient, stressing that they must not unilaterally cease
pre extraction hyperbaric oxygen for 20 treatments.17 their medication. The more medically complex the
Established ORN which most sufferers describe as patient is and the more extensive the procedure then
being worse than their original cancer similarly need the more the general dental practitioner should con-
more hyperbaric oxygen therapy and surgery.18 Such sider specialist referral.
patients are best treated by specialist experienced in
management of this condition. Failure to follow these Medication related hyposalivation
requirements may result in chronic pain and suffering
for the patient and medico legal consequences for the With our aging population the issue of medication
dentist. related reduction in salivation is an increasing issue.23
The consequences of this dry mouth are increased
smooth surface decay and periodontal disease.23
Anticoagulants and antiplatelet drugs Extractions and dentures are not necessarily the
answer because the dry mouth results in difficulties in
An increasing number of patients are on medications denture wearing. This may be complicated by
to decrease the coagulation of their blood. This may increased cognitive decline with consequential effects
be both prevention and therapeutic management of a on oral hygiene and difficulty learning how to use a
wide range of cardiovascular and haematologic condi- prosthesis. An important subgroup of patients with
tions. Hence again the first issue is what is the patient’ medication related salivary flow reduction have
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Contemporary exodontia

chronic pain, are on extensive amounts of narcotics is best used sparingly. If the patient asks for narcotics
and antidepressants. They are usually younger, so by name – beware.
have more time for their dentition to fail. Again pre-
vention is better than cure. Discussion with the
Antibiotic prophylaxis
patient’s prescribing medical practitioner about the
oral consequences of the medication; dry mouth man- The indications for prophylactic antibiotics in Aus-
agement with local pharmacologic agents; strengthen- tralia have been greatly restricted for extractions, they
ing the tooth resistance with fluoride and ongoing are not required for patients with artificial joints and
oral hygiene training, involving the family and nursing the number of indicated cardiac conditions is greatly
home as necessary. Careful consideration of individual reduced.8 In the United Kingdom the NICE guidelines
teeth for conservation or extraction is at a whole indicate no cardiac condition requires antibiotic pro-
patient level. Remember implants are not necessarily phylaxis.26 This has results in a 75% reduction in the
the answer as the patient may be physically incapable prescription of Amoxicillin 2 g prescription and no
of withstanding the procedure and caring for the discernible increase in endocarditis.27
reconstruction. Cost is a significant barrier also. There is no indication for antibiotics after routine
extractions in healthy patients and there is no evi-
dence that antibiotics reduce post extraction infection
Pharmacologic management of patients undergoing
even in immunocompromised patients. Dentists do
extraction
have an important role in reducing the prescription of
Appropriate prescription of medications is an essential antibiotics as part of overall antibiotic steward-
accompaniment of exodontia although sometimes this ship.8,28 The last seventy years of over prescription of
involves the avoidance of medications, knowing what antibiotics has resulted in the rise of antibiotic resis-
not to prescribe is often more important than know- tant microorganisms.
ing what to prescribe. The key areas relate to seda- Exodontia is the cornerstone procedure in den-
tion, analgesics and antibiotics. Besides local toalveolar surgery. Care and maintenance of the alve-
anaesthetic, oral sedation with the benzodiazepines is olus is paramount. Other dentoalveolar procedures
a useful adjunct. The dose relates to the patient’s anx- are discussed in the papers on impacted teeth,29 and
iety, previous benzodiazepine experience and the single tooth replacement implants.30
extent of the procedure. The patient should be
escorted and must not drive.
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