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Procedure:
You will need to take a picture of each phase of Meiosis after it is set up and upload the
image to your data table below!
1. Interphase 1:
a. Obtain 4 gummy worms and cut them in half vertically (cut down the entire
length) and place them on a clean paper plate. Note- each half of a gummy
worm will count as 1 chromatid.
2. Prophase 1:
a. Create 2 pairs of sister chromatids with the 8 pieces of gummy worms. Note-
make sure you put the matching colors together
b. Cut off 1 cm from the
bottom of one
chromatid from each
pair and switch them
to indicate crossing
over (see image).
3. Metaphase 1:
a. Line Homologous Chromosomes down the middle of the cell (paper plate)
4. Anaphase 1:
a. Take each of the Homologous chromosomes and move them to opposite
ends of the cell.
i. Note: have 2 students act as the mitotic Spindles that pull the
chromosomes apart.
5. Telophase 1 & Cytokinesis
a. As the cell starts to divide into two cells it starts to form a
cleavage furrow. Cut the “cell” partway to represent this.
b. Eventually, cut the “cell all the way across to show that
cytokinesis has occurred.
6. Prophase 2:
a. You should now have 2 separate plates “cells” with two
pairs/sets of sister chromatids each
7. Metaphase 2:
a. Line the chromosomes along the middle of each cell
8. Anaphase 2:
a. Split the two chromosomes apart and move them to opposite ends of the
cells
9. Telophase 2/Cytokinesis:
a. Both cells split in half, creating 4 daughter cells (4 plates)
b. Each should have 2 single-stranded chromatids (gummy worms) each
Data Table:
Interphase 1 In Interphase I
chromosomes
duplicate, mom
chromosomes get
together and dad
chromosomes get
together too.
Prophase 1 In Prophase 1
homologous
chromosomes pair
up, they cross over
between nonsister
chromatids
Metaphase 1 In Metaphase I
homologous pairs
line up in the middle
of the cell together
Anaphase 1 In anaphase I
homologous
chromosomes are
pulled apart to
opposite sides of the
cell.
Metaphase 2 In metaphase II
duplicated
chromosomes line
up individually in the
middle of the cell,
not with their
homologous pair
Anaphase 2 In Anaphase II sisters
chromatids are
pulled apart to
opposite sides of the
cell
Conclusion Questions: Answer all questions below, make sure to highlight your answer for
each question
1. What is the purpose of Meiosis? ANSWER
2. What are homologous chromosomes?
3. At Which stage are there homologous chromosomes lined up down the middle of
the cell?
4. At Which stage are their sister chromatids lined up down the middle of the cell?
5. What does it mean to be diploid?
6. What does it mean to be haploid?
7. At the end of Meiosis I
a. How many cells are there?
b. Are they haploid or diploid?
8. At the end of Meiosis II
a. How many cells are there?
b. Are they haploid or diploid?
9. What would the 4 final cells look like if crossing over did not occur?
10. Drawing Conclusions: Look at your four gametes. How does meiosis lead to
increased genetic variation?
11. Understanding: What is meant by the statement that Meiosis results in gene
segregation?
12. Predicting: How would the gametes be affected if a pair of chromatids failed to
separate in the second meiotic division?
Crossing-over occurs
Chromatids separate