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KEYWORDS
Central venous access Internal jugular vein catheterization Subclavian vein catheterization
Femoral vein catheterization Vascular access Catheter
KEY POINTS
Central venous access can be obtained if peripheral venous access is inadequate or if there is a need for total parenteral
nutrition administration, invasive hemodynamic monitoring, transvenous pacing, and placement of pulmonary artery
catheters.
Absolute contraindications to central venous access are venous thrombosis, untreated coagulopathy, thrombocytopenia
(<50,000), fungating tricuspid valve endocarditis, and renal cell tumor extending into the right atrium.
Femoral venous access is used as a site of last resort because of the increased risk of thrombosis, embolism, and infection.
Complications associated with central venous catheterization include catheter misplacement, arterial puncture, hemor-
rhage, pneumothorax, thoracic duct injury, extravasation of fluids, medications, hyperalimentation, dysrhythmias,
brachial plexus injury, air embolism, catheter or wire embolization, hydrothorax, thrombosis, and infection (central-line-
associated bloodstream infection [CLABSI]).
Complications can be minimized by good sterile technique during placement, proper patient positioning and procedure
performance, appropriate catheter maintenance postplacement, and proper removal technique.
Use of image guidance should be considered if available to improve success and reduce the incidence of complications.
Introduction use are Hickman, Groshong, and Broviac catheters. There are
also various implantable ports that can be placed to maintain
A German surgical resident, Werner Forssmann, self-cathe- long-term central venous access. Absolute contraindications to
terized one of his own left antecubital veins and then radio- central venous access are venous thrombosis, untreated coa-
graphically confirmed the tip placement within his right atrium gulopathy, thrombocytopenia (<50,000), fungating tricuspid
in 1929. Thus began a new era in venous access for multiple valve endocarditis, and renal cell tumor extending into the
purposes. At present, in the United States alone almost 15 right atrium. Anticoagulation is a relative contraindication (Box
million central venous access procedures are performed 2).
annually. Patients presenting for surgical procedures using This article discusses obtaining central venous access with
intravascular administration of medication, patients present- multilumen Silastic catheters in 3 sites: internal jugular vein,
ing to the emergency department for acute care, and most subclavian vein, and femoral vein.
patients admitted to the hospital require some sort of vascular
access device. For most of these patients, a peripheral venous Equipment
access device suffices with low morbidity. Upper extremity
veins are the most recommended and used veins including the Arrow Pressure Injectable Multi-Lumen CVC Kit or similar
median, basilic, and cephalic veins. Lower extremity venous (Box 3, Figs. 1 and 2).
access can also be achieved but has a much higher complica- ChloraPrep or povidone-iodine scrub (if not included in the
tion rate of phlebitis and infection and is not routinely kit).
recommended. Absorbent pads (Chux pads).
Central venous access can be obtained if peripheral venous
access is inadequate or if there is a need for total parenteral Internal jugular venous access
nutrition administration, invasive hemodynamic monitoring,
transvenous pacing, and placement of pulmonary artery cath- A specific contraindication to internal jugular venous access is
eters (Box 1). Large vessel lumens lessen the risks of vessel ipsilateral carotid endarterectomy if image guidance is not
irritation and phlebitis and provide rapid administration of used. Internal jugular catheterization is intermediate in risk
medications to the central circulation. A few catheter types in between subclavian venous catheterization and femoral artery
catheterization for postplacement infection.
Disclosures: The author has no financial conflicts or disclosures
related to this topic. Pertinent anatomy
Oral and Maxillofacial Surgery, 9107 Whistling Swan Lane, Manlius, The internal jugular vein arises at the base of the skull and is
NY 13104, USA located in the carotid sheath posterior to the internal carotid
E-mail address: dr.bourgeois@twcny.rr.com artery. The internal jugular vein terminates as the subclavian
Box 1. Indications for central venous access Box 3. Contents of Arrow Pressure Injectable
Multi-Lumen CVC Kit, CDC-45703-XP1A
Inadequate peripheral venous access (Teleflex, Morrisville, NC)
Need for total parenteral nutrition administration
Invasive hemodynamic monitoring Multilumen indwelling catheter 7F 20 cm (16 and
Transvenous pacing 30 cm catheter lengths are also available)
Placement of pulmonary artery catheters Spring-wire guide, marked 0.81 mm 60 cm
18-gauge 2.5-in catheter, with 20-gauge needle
vein anterior and lateral to the common carotid artery. The Pressure transduction probe
course of the internal jugular vein is medial to the sterno- Injection needle, 22 gauge 1.5 in
cleidomastoid muscle at its superior extent and posterior in the Injection needle, 25 gauge 1 in
triangle formed by the sternal and clavicular heads. At the 3-mL Luer lock syringe
inferior part, the vein is deep to the clavicular head (Figs. 3 5-mL Luer lock syringe
and 4). Introducer needle, echogenic, 18 gauge 2.5 in
5-mL Arrow Raulerson (Teleflex, Morrisville, NC) spring-
Technique wire introduction syringe
There are 2 approaches for internal jugular venous catheteri- Tissue dilator
zation, the central approach and the posterior approach. Right 3-mL applicator pouch, 2% chlorhexidine gluconate, and
internal jugular veins have the straightest course to the right 70% isopropyl alcohol ChloraPrep one-step solution with
atrium and the lowest complication rate. Hi-Lite Orange tint
5-mL ampule 1% lidocaine solution
1 pack 62% alcohol hand gel
Central approach
10-mL Luer lock syringe (quantity 2)
1. Place absorbent pads beneath the patient (Fig. 5).
Catheter clamp
2. Position patient in Trendelenburg position.
Fastener, catheter clamp
3. Rotate the patient’s head 45 to the contralateral side.
SharpsAway II, locking disposal cup
4. Locate the apex of the triangle formed by the heads of the
CSR wraps
sternocleidomastoid muscle and the clavicle.
Maximal barrier drape with 4-in fenestration
5. Prepare and drape the neck.
Towel
6. Scrub and gown for sterile procedure.
Needle holder
7. Using the 3-mL Luer lock syringe and 25-gauge needle,
Safety scalpel, No. 11 blade
anesthetize the skin and subcutaneous tissues at the apex
Checklist/CLIP (Central Line Insertion Practices) sheet
of the triangle.
Flow rate information card with injection log
8. Palpate the carotid pulse and apply gentle medial traction.
Medication label, 1% lidocaine
9. Insert the finder needle, 22 gauge with a 5-mL Luer lock
Sterile procedure sign
syringe attached, at the apex of the triangle at a 45 to 60
Dressing, BIOPATCH (Ethicon, Cincinnati, OH)
angle to the skin surface advancing slowly toward the
Dressing, Tegaderm (3M, St. Paul, MN), 10 cm 12 cm
ipsilateral nipple and aspirating.
Gauze pads, 2 in 2 in; quantity 2
a. If venous blood return is not noted after the needle has
Gauze pads, 4 in 4 in; quantity 5
been inserted 3 cm, slowly withdraw the needle while
Surgical apparel: bouffant cap, impervious gown, mask
aspirating.
with eye shield
b. If venous blood return is still not noted, reintroduce the
3-0 silk suture with curved needle
needle through the same puncture site but direct the
HemoHopper (Teleflex, Morrisville, NC) fluid receptacle
needle 1 to 3 cm more laterally.
c. If venous blood return is still not noted, reintroduce the
needle through the same puncture site but direct the
needle 1 cm medially. a Raulerson syringe on the introducer needle, follow the
d. If venous blood return is still not noted, consider tract of the finder needle while aspirating.
changing to the posterior approach. 11. Once venous blood return is noted in the introducer nee-
10. If good venous blood return is noted, leave the finder dle, insert the guidewire through the Raulerson syringe
needle in place as a guide for the introducer needle. Using (Seldinger technique). If a Raulerson syringe is not avail-
able, remove the syringe and occlude the needle to pre-
vent air embolism and then introduce the guidewire.
Box 2. Contraindications to central venous a. Never lose control of the guidewire (Fig. 6).
access b. The guidewire should advance freely.
c. If resistance is encountered, remove the wire and
Venous thrombosis confirm positive venous blood return before reintro-
Untreated coagulopathy ducing the guidewire.
Thrombocytopenia (<50,000) d. Insert the wire to about 20 cm.
Fungating tricuspid valve endocarditis 12. Make a nick in the skin with the scalpel blade.
Renal cell tumor extending into the right atrium 13. Place the dilator over the guidewire and push the dilator
Anticoagulation (relative contraindication) into the vein. Do not push the dilator in more than half its
length to avoid vein injury.
Central Venous Access Techniques 139
14. Insert catheter over the guidewire to proper depth (15 cm Pertinent anatomy
for right internal jugular catheterization and 17 cm for left The subclavian vein is a continuation of the axillary vein at the
internal jugular catheterization). lateral border of the first rib. The vein passes over the first rib
15. Remove the guidewire. anterior to the anterior scalene muscle. The vein then courses
16. Secure the line to the skin with suture. deep to the medial third of the clavicle. The subclavian vein
17. Aspirate each lumen to fill line with blood, then flush with then joins with the internal jugular vein to form the innomi-
a saline flush, clearing all blood from each lumen. nate vein deep to the sternoclavicular joint. At the medial
18. Place appropriate sterile dressing over site. third of the clavicle, the subclavian artery and apical pleura
19. Obtain chest radiograph to verify catheter position. are deep to the vein (Fig. 8).
Fig. 8 Pertinent regional anatomy for subclavian venous access. (From MacLennan SE. Chapter 70. Vascular access techniques. In: Berry
SM, editor. The Mont Reid surgical handbook. 4th edition. St Louis (MO): Mosby-Year Book, Inc; 1997. p. 674; with permission.)
142 Bourgeois Jr
A sterile dressing is applied over the catheter; the dressing Fig. 12 Chest radiograph demonstrating proper catheter tip
should be changed weekly. Topical antibiotic use at the location. AP, anteroposterior.
insertion site has not been shown to reduce CLABSI rates and is
not recommended. Catheters should not be routinely replaced Although controversial, it can be argued that ultrasound-
unless there is evidence of localized infection or sepsis. It is guided central venous access is the current standard of care. If
recommended that the infusion tubing be changed every 48 to ultrasound-guided vascular access is used, it is recommended
72 hours. Confirmation of internal jugular and subclavian that a long, sterile sheath be used to cover the ultrasound
catheters by chest imaging is recommended. The catheter tip probe. Also, use of a real-time image acquisition technique is
should lie within the superior vena cava, outside of the right preferred. Operator experience and skill in the technique are
atrium. On chest radiographs for internal jugular and subcla- important factors for success.
vian vein catheters, the tip should lie above the level of the
carina (Box 5, Fig. 12).
Summary
Removal of catheters Central venous access remains a vital part of hospital-based
medical treatment when inadequate peripheral venous access
It is recommended to remove central venous catheters as soon as is identified or when hemodynamic monitoring and hyperali-
the patient’s medical condition has improved to the point where mentation are required. Complication costs and morbidity and
central venous access is no longer required. For internal jugular mortality with central venous access are significant. All surgi-
and subclavian catheters, the patient is positioned in the Tren- cal specialists should be familiar with the relevant anatomy,
delenburg position and removal of the catheter is synchronized indications, and contraindications of central line placement;
with active exhalation if the patient is awake, cooperative, and placement techniques; catheter maintenance procedures; and
spontaneously breathing. In cooperative patients, the Valsalva prevention of complications. Subclavian venous access fol-
maneuver is recommended over breath holding to reduce the lowed by internal jugular venous access is preferred over
risk of an air embolism. Special attention should be paid to oc- femoral venous access. Over the past 2 decades, image-guided
clusion of the entry site on catheter removal. placement is becoming more commonplace and has reduced
but not eliminated the incidence of complications with
Evolving technology placement of central venous catheters.
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Halstead Residents of The Johns Hopkins Hospital. Chapter 2. Arter- York: McGraw-Hill; 2010. Available at: http://accessanesthesiology.
ial/venous access. In: Chen H, Lillemoe KD, Sola JE, editors. Manual mhmedical.com/content.aspx?bookidZ419&SectionidZ41482857.
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editor. The Mont Reid surgical handbook. 4th edition. St Louis (MO): cess: a comprehensive review. J Cardiothorac Vasc Anesth 2013;
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