9.

1 Speciation of the microfilariae can be done by recog- nition of the distribution of nuclei in the
tip of the tail and the presence or absence of a delicate transparent covering known as the:
(Objective 9-1)

A. Flilariform
B. Cuticle
C. Sheath
D. Nucleus

What type of periodicity is exhibited if microfilariae appear in the blood of an individual at 2:00
p.m. each day? (Objective 9-1)
A. Nocturnal
B. Diurnal
C. Subperiodic
D. Biannual

Which of the following is similar for all microfilariae discussed? (Objective 9-13)
A. Presence of a sheath
B. Ability to exhibit periodicity
C. Location of the adult worms
D. The basic life cycle

Diagnosis of infection with Wuchereria bancrofti is best accomplished by: (Objective 9-8)
A. Examination of stained peripheral blood taken
during the night
B. Examination of stained tissue biopsy taken during
the night
C. Use of serologic testing with blood taken during
the day
D. Examination of stained lymph fluid taken during
the day

Which of the following, in combination with alben- dazole, has proven to be an important drug
for the treatment of Bancroft’s filariasis? (Objective 9-9C)
A. Doxycycline
B. Ivermectin
C. Metronidazole
D. None of the above

Which of the following can be used in the differentia- tion and identification of Brugia malayi?
9-13)
A. Absence of a sheath
B. Absence of nuclei in the tail
C.Presenceofasheaththatisverydifficulttoobserve
on Giemsa stain
D. Presence of two terminal nuclei in the tail

Select the ideal time period to collect blood samples for examination for the presence of the
microfilariae of Brugia malayi. (Objective 9-8)
A. 10:00 p.m. to 4:00 a.m.
B. 10:00 a.m. to 4:00 p.m.
C. 4:00 p.m. to 8:00 p.m.
D. Any time of the day or night

A small threadlike worm is observed under the con- junctiva of the eye. What organism and form
is most likely? (Objective 9-8)
A. Wuchereria bancrofti adult
B. Brugia malayi microfilaria
C. Onchocera volvulus larva
D. Loa loa adult

What type of periodicity does Loa loa exhibit? (Objec- tive 9-8)
A. Nocturnal
B. Subperiodic
C. Diurnal
D. None

9.10 How do the microfilariae of Onchocerca volvulus differ from those of other filarial?
(Objective 9-13)
A. The presence of a sheath.
B. Nuclei are present continuous to the end of the
tail
C. They exhibit diurnal periodicity
D. They are found in the skin rather than blood

9.11 Skin snips are the specimen of choice for diagnosis of infection with: (Objective 9-8)
A. Loa loa
B. Onchocerca volvulus
C. Brugia malayi
D. Wuchereria bancrofti

How are the microfilariae of Mansonella ozzardi differentiated from those of Ochocerca
volvulus? (Objective 9-13)
A. Location of the microfilariae
B. Absence of a sheath
C. Lack of terminal nuclei in the tail
D. Presence of a sheath
Which of the following filarial drugs is effective against Mansonella ozzardi if therapy is
necesary? (Objective 9-9)
A. Albendazole
B. Diethylcarbamazine
C. Doxycycline
D. Ivermectin

If a physician suspects an individual has the potential for infection with Mansonella perstans,
what speci- men type would you suggest for recovery of the organism? (Objective 9-8)
A. Skin snips
B. Lymphatic fluid
C. Blood
D. Infected nodules

What type of periodicity does Mansonella perstans exhibit? (Objective 9-8)

A. Nocturnal
B. Diurnal
C. Subperiodic
D. None

9-1. You live by a fast moving river in Eastern Africa. Which of the following filarial nematodes
poses the greatest risk of infec- tion for you? (Objective 9-5)
A. Brugia malayi
B. Onchocerca volvulus C. Wuchereria bancrofti D. Loa loa
9-2. Which of the following filarial nematodes is known as the blinding filaria? (Objective 9-3)
A. Brugia malayi
B. Onchocera volvulus C. Loa loa
D. Mansonella ozzardi
9-3. The microfilariae of Brugia malayi are rec- ognized by the: (Objective 9-11)
A. presence of a sheath and two distinct
terminal nuclei in the tail
B. presence of a sheath and absence of
nuclei in the tail
C. absence of a sheath and nuclei continu-
ous to the tip of the tail
D. absence of a sheath and absence of nuclei in the tail
9-4. Which of the filarial nematodes uses the mosquito as its vector?(Objective 9-5)
A. Loa loa
B. Onchocera volvulus
C. Wuchereria bancrofti
D. Mansonella ozzardi
9-5. Swelling of the lower extremities due to
obstruction of the lymphatic system by adult filarial nematodes is known as: (Objective 9-1)
A. Periodicity
B. Lymphangitis C. Eosinophilia D. Elephantiasis
9-6. All of the following microfilariae lack a sheath except: (Objective 9-13)
A. Mansonella ozzardi
B. Mansonella perstans
C. Onchocera volvulus
D. Brugia malayi
9-7. 9-7. Diagnosis of infection with Wuchereria
bancrofti can be accomplished by all of the following methods except: (Objective 9-8) A.
Serologic testing
B. Tissue biopsies
C. Knott technique
D. Thick and thin peripheral blood smears 9-8. Which of the following filarial nema- todes is
transmitted by the Chrysops fly?
(Objective 9-6)
A. Onchocerca volvulus B. Mansonella ozzardi C. Loa loa
D. Brugia malayi
9-9. Which of the following filarial nematode infections is diagnosed by using skin snips rather
than a peripheral blood smear? (Objective 9-8)
A. Onchocerca volvulus B. Loa loa
C. Mansonella perstans D. Wuchereria bancrofti
9-10. If an individual was planning to visit Africa, which of the following filarial nem- atodes
would not be a concern for poten- tial infection? (Objective 9-2)
A. Loa loa
B. Wuchereria bancrofti C. Brugia malayi
D. Mansonella ozzardi