Book Notices

The Neurochemistry cf Nucleotides and A m i m Acads.
Edited by ROSCOE0. BRADYand DONALDB.
TOWER. John Wiley & Sons, 440 Fourth Ave.,
New York 16, N. Y., 1960. xii + 292 pp. 14.5
X 23 cm. Price $10.
This book covers the symposium of the Section on
Neurochemistry of the American Academy of
Neurology held -4pril 24-25, 1958. Papers are
followed by discussions, with a general summary dis-
cussion. Author and subject indexes are appended.
Advances i n Pest Control Research. Vol. 3 .
Edited by R. L. METCALP. Interscience Publish-
ers, Inc., 250 Fifth Ave., New York 1, N. Y.,
1960. vii + 448 pp. 15.5 X 23 cm. Price
$14.50.
This third volume of the series continues the
excellent reporting in this special field. Volumes I
and I1 were reviewed, respectively, in THISJOUR-
NAL,47,230( 1958), and 48,258( 1959).

Staining Procedures. 2nd ed. Revised by H. J. The Search for New Antibiotics. By G. F. GAUSE.
CONN,MARYA. DARROW, and VICTORM. EMMEL. Yale University Press, New Haven, Conn., 1960.
The Williams & Wilkins Co., 428 East Preston x+ 97 pp. 14 X 21.5 cm. Price $4.75.
St., Baltimore 2, Md., 1960. xii + 289 pp. 15 This second volume in the Trends in Science pro-
gram is based on a lecture in December 1959 by G. F.
X 23 cm. Paperbound. Price $5.
This is an authoritative compilation of staining Gause, Director of the Institute of Antibiotics of the
procedures used by the Biological Stain Commission, Academy of Medical Sciences, Moscow, U. S. S. R.
University of Rochester Medical Center. The pro- Principles which are known and represent the scien-
cedures are not intended t o be considered as stand- tific basis of the search for new antibiotics are given
ard or official but they are presented in a stand- by Gause as: A general microbiological approach to
ardized style for the convenience of users. A given the geography and ecology of microorganisms pro-
procedure is frequently one of a number of ways of ducing antibiotics; Early classification of micro-
obtaining good staining results. However, one can organisms in the screening program; and Develop-
rely on the tested methods dFscribed. A bibliog- ment of new test organisms for rapid detection of
raphy and subject index are appended. specific selective inhibition of some biochemical
mechanisms, as illustrated by the search for poten-
tial anticancer products.
Nucleoproteins. Edited by R. STOOPS.Inter-
science Publishers, Inc., 250 Fifth Ave., New
York 1, N. Y., 1960. 364 pp. 16 X 24.5 cm. British National Formulary 1960. Alternative
Price $10.50. Edition. The British Medical Association and
This book records the proceedings of the eleventh the Pharmaceutical Society of Great Britain.
Solvay conference on chemistry held June 14.1959, The Pharmaceutical Press, London, England,
at Brussels, Belgium. Paper titles are: Le r d e 1960. Obtainable in the U. S. from The Ritten-
biologique des acides nucleiques, Molecular struc- house Bookstore, 1706 Rittenhouse Sq., Phila-
ture of deoxyribonucleoproteins, Constitution of delphia, Pa. 292 pp. 10.5 X 16.5 cm. Price
histones, Les propri6t6s physiques de l’acide d6- $1.75, interleaved $2.25.
soxyribonucl6ique en solution, Heterogeneity of This “alternative” edition of the B. N. F. 1960
nucleic acids and effects of chemical and physical contains much of the same information as does the
agents, Nucleic acids of microorganisms, Biosynthe- standard edition; but the arrangement of the drug
sis of ribonucleic acid, Formation of helical poly- section in this edition is based on a pharmacological
nucleotide complexes, Structure of RNA containing classification. These books are intended as guides
viruses, and Chemical synthesis of polynucleotides. in prescribing.
Each paper is discussed and a general discussion is
included. No index.
A n Introduction to Pharmac~logy. By J. J. LEWIS.
Radioactivity for Pharmaceutical and Allied Research E. and S. Livingstone Ltd., Edinburgh and Lon-
Laboratories. Edited by ABRAHAM EDELMANN. don, 1960. Exclusive U. S. agents, The Williams
Academic Press, Inc., 111Fifth Ave., New York3, & Wilkins Co., 428 East Preston St., Baltimore 2,
N. Y., 1960. xii + 171 pp. 13 X 20.5 cm. +
Md. xii 826 pp. 14 X 21.5 cm. Price $11.
Price $6. This book stresses the site, mode, and type of
This little book includes the papers presented a t a action of drugs, with attention to chemical structure
symposium sponsored by Nuclear Science and En- and action relationships. It indicates the lack of
gineering Corporation. Subjects discussed include : knowledge of modes of action of some of the most
Effects and utilization of ionizing radiation; Princi- widely used drugs and develops the text material to
ples, methods, and areas of usefulness of radio- inspire further research. This is to be expected
activity in the pharmaceutical and allied sciences : from an author who is still actively engaged in re-
assays, product development, drug absorption, and search in this field. The text material is presented
excretion ; and Radiobiochemistry in the pharma- in a n interesting manner, omitting details available
ceutical industry. The isotope development pro- in more comprehensive publications. I t is a good
gram of the Atomic Energy Commission is reviewed. review and reference book.
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