Immunology seminar questions

Quiz 1, 2
Innate Immune System
Points:
27/30
1.Which of the following statements is TRUE of C3b?
(3/3 Points)
C3b is chemotactic for neutrophils
C3b is an anaphylatoxin
C3b opsonizes bacteria
C3b directly injures bacteria
C3b is the inactive form of C3
2.The membrane attack complex consists of:
(3/3 Points)
OH
Colicins
C3bBb3b
C5b,6,7,8,9
Properdin
3.Innate immunity
(3/3 Points)
Is slower than adaptive immunity in responding to pathogens.
Is nonspecific and present at birth.
Involves a memory component.
Involves T cells and B cells.
Provides increased susceptibility to disease.
4.All the 'patterns' trigger:
(3/3 Points)
B cell
T cell
Thymus involution
Reactions of the innate immunity
5.Secondary Immune Organs are:
(3/3 Points)
 Limph nodes, spleen, MULT
Limph nodes and Bone marrow
Bone marrow, spleen and MULT
Bone marrow and Tymus
Tyimus, limph node and tonsiles
6. Which of the following is a complement component that is strongly
chemotactic for neutrophils?
(3/3 Points)
C9
C5a
C3
C3b
C5b
7. Which of the following does the mononuclear phagocyte system NOT include?
(3/3 Points)
Monocytes
Kupffer cells
Kidney mesangial cells
Lymph node medullary macrophages
Endothelial cells
8.Match the following innate immune system cell types with their function:
Macrophage
(3/3 Points)
Lysis of some virally infected cells
Killing parasites
Release of histamine a Other mediators
Phagocytosis and bacteriocidal mechanisms
9.Which of the following does NOT protect body surfaces?
(3/3 Points)
Skin
Mucus
Gut microflora
Amylase in saliva
10.Neutrophil defensins are:
(0/3 Points)
 Anti-toxins
Oxygen-dependent
Enzymes
Peptide antibiotics
Glycolipids

Quiz N 3,2
Cellular Immunity

Points:
27/30
1. What is CD8 a marker of?
(3/3 Points)

B-cells

B Helper T-cells

Cytotoxic T-cells

An activated macrophage

A neutrophil precursor

2.Which of the following statements is TRUE of CD4?

(3/3 Points)

CD4 binds to MHC class II on antigen-presenting cells

CD4 binds to MHC class II on eosinophil

CD4 binds processed peptide in its outer groove

CD4 binds to MHC class II on NK cells

3.CTL Cells
(3/3 Points)

Releases perforin and granzymes

Release histamin and leucotrien

Release INF gamma and TNF alpha

Release Basic protein and neurotoxin

Release IL - 4 and IL - 5

4.Which of the following is characteristically produced by the Th2 CD4 cells

which provide help for antibody production, but not by Th1 cells?
(3/3 Points)

IFNγ

Lymphotoxin (TNFβ)

Granulocyte–macrophage colony-stimulating factor (GM-CSF)

IL-4

IL-1

5.HLAs corresponding to MHC class I present peptides

(3/3 Points)

from inside the cell to CD8+ cells

from inside the cell to CD4+ cell

from outside of the cell to M cell

from outside of the cell to B cell

from outside of the cell to TH

6.Which of the following are NOT APC?

(3/3 Points)

DC (dendritic cells)
 B Cells

Neutrofills

Macrophages

7.T cells respond to Ag by

(3/3 Points)

BCR

Toll like receptor

Nod like receptor

KIR and KAR receptor

TCR

8.Cytokines always act:

(3/3 Points)

In an autocrine fashion

By binding to specific receptors

In an autocrine fashion

At long range

Antagonistically with other cytokines

9.TH17 produce
(3/3 Points)

IL 4

IL 5

INF gamma

IL 17
 INF alpha

10.IFNγ and TNF (TNFα) are produced by

(0/3 Points)

T regulatory cells

Natural killers

Th2

Th 1- correct answer

Th17

quiz N 5,2
Points:
30/30
1. The type I late response occurs hours later and involves the following
mediators.

(3/3 Points)

IL4

IL-5

TNF-α

All of the above

2.Type IV hypersensitivity is mediated by

(3/3 Points)

Erythrocytes

Neutrophils
 Eosinophils

T cells

3.The transfer of tissue between genetically identical individuals is calld:

(3/3 Points)

Autograft

Xenograft

Allogradraft

Syngeneic graft

4.What type of cells are generally found in lower concentration in autoimmune

disease?
(3/3 Points)

T cells

B cells

Treg

Macrophages

CTL

5.The principal antibodies involved in type II hypersensitivity are

(3/3 Points)

IgA and IgG

IgA and IgD

IgG and IgM

IgD and IgB

IgG and IgE

6.An example of a type III immune complex disease is:

(3/3 Points)

Contact dermatitis

Diabetes

Serum sickness

Atopy

Allergies

7.Which of these is an autoimmune disease?

(3/3 Points)

Type 1 diabetes

Rheumatoid arthritis

Psoriasis

AIDS

A, B, and C

8.Contact with poison ivy would elicit which type of hypersensitivity reaction?
(3/3 Points)

type III

type I

type II

type IV

type V

9.The major molecules responsible for rejection of transplant is

(3/3 Points)

B cells
 T cells

MHC molecule

Antibodies

10.Which of the following is not an example of Type I hypersensitivity reaction?

(3/3 Points)

Asthma

Allergic Rhinitis

Systemic Lupus Erythematosus

Atopic Dermatitis