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B. PHARM

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(SEM-I) THEORY EXAMINATION, 2019-20

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BIOCHEMISTRY
Time: 3 Hours Total Marks: 75

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Note: 1. Attempt all Sections. If require any missing data; then choose suitably.

SECTION A
1. Attempt all questions in brief. 10 x 2 20
a. Define electron tranport chain?
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b. Define free energy?
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c. What is hyperbilirubinemia?
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d. Define redox potential?
e. What is jaundice?
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f. Define vitamin D?
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g. What are the full form of NADH,ATP,TPP,UDP.UTP,NADPH?
h. Define gout?
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Draw the structure ofATP?
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Define cholestrol?
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SECTIONB Ca
2. Attempt any twoparts of the following: 2x 10= 20
a. Write the classification of protein?
|b. Write the pathway of glycolysis and its energitics?
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C. Define lipids with its classification?


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SECTION C
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3. Attempt any siveparts of the following: 7 x5 35
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a. Define enzyme kinetics and write down the properties of enzymes?


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b. Write the structure of DNA and RNA?


Write a note on conversion of cholestrol into bile acid and its role?
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d. Write a short note on


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i).Genetic code
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ii).Hypercholesterolemia
e. Describe Coenzyme with its structure and biological function?

f.Write glycogen metabolism pathway ?


g. Write the biosynthesis of ketone bodies and their utilization?
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Page 2 of 4
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CAREWELL PHARMA

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B PHARM
(SEM-ID THEORY EXAMINATION 2019-20

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HUMAN ANATOMY AND PATHOPHYSIOLOGY-II

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Time: 3 Hours Total Marks: 75
Note: 1. Attempt all Sections. If require any missing data; then choose suitably.
2. Any special paper specific instruction.

SECTION A
1. Attempt all questions in brief. 10 x 2 20
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a. What is an action potential
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b. What are the name of lobes of cerebral hemisphere
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c. What is the role of the mouth in digestive system
d. Differentiate between vital capacity and total lung capacity.
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c. Define Glomerular Filtration Rate (GFR).
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f Give the name of disorders of the male reproductive system.
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g. Define asthma and Pneumonia.
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h. Enlist the function of hormones.
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i. Briefly explain cushing syndrome.
j. Where does the fertilization take place in the female?
SECTIONB
2. Attempt any two parts of the following: 2 x 10 20
a. Describe cerebrospinal fluid and its circulation
II. Describe the structure and functions of medulla oblongata.
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b. Define ovulation. Explain different phases of the female reproductive cycle
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c. Describe the mechanism of ATP Formation.
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SECTIONC
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3. Attempt any five parts of the following: 7 x535


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a. Explain the events of signal transmission at a chemical synapse.


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b. Describe the surface anatomy of lungs along with suitable diagrams.


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c. Describe the hormones of Pancreas and their physiological role.


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d. Describe different parts and types of Nephron.


e. What is BMR and how it is determined? Describe various factors affecting BMR.
f. Write a short note on gland of Emergency.
g. Detine Genetics. Write a short note on chromosomes.
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Page 3 of 4
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CAREWELL PHARMA

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B. PHARM

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(SEM-I) THEORY EXAMINATION 2019-20

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PATHOPHYSIOLOGY
Time: 3 Hours Total Marks: 75

Ca

Ca
Note: 1. Attempt all Sections. If require any missing data; then choose suitably.

SECTION A
1. Attempt all questions in brief. 10 x 2 20
a. Define cellular adaptations.
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b. What are intracellular accumulations?
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c. Describe Myocardial infarction in brief.
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d. Give a short note on Hemophilia.
e. Define Angiogenesis.
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f.Write a note on role of interleukins in inflammation process.
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g. Give a short note on hypothyroidism and possible reasons for its development.
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h. Tuberculosis.
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i. Short note on ulcerative colitis.
j. Discuss the sign and symptoms of Leprosy.
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SECTION B Ca
2. Attempt any two parts of the following: 2 x 10 20
a. Write in detail the pathophysiology of Parkinson's disease. Explain intrinsic and
extrinsic pathways.
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b. Discuss the pathophysiology of atherosclerosis and hypertension.


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c. Explain the process of apoptosis. Elaborate extrinsic and intrinsic pathways.
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SECTION C
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3. Attempt any five parts of the following: 7 x5 35


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a. Give the pathophysiology of Asthma.


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b. Define Anemia. Elaborate Iron Deficiency Anemia.


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c. Give the pathophysiology of Epilepsy. Explain its various types.


d. Define Ulcers. Explain the process of ulcer development.
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e. Differentiate between rheumatoid and osteoarthritis. Explain the pathophysiology of


osteoarthritis.
Describe the pathways of development of cancer.
g. Explain the pathophysiology of AIDS.
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CAREWELL PHARMA

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B PHARM
(SEM-ID THEORY EXAMINATION 2018-19

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PHARMACEUTICAL ORGANIC CHEMISTRY-I

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Time: 3 Hours Total Marks: 75
Note: Attempt all Sections. If you require any missing data, choose suitably.

SECTION A
1. Attempt all questions in brief. 10 x 2 20
a. Give IUPAC name for (CH)C=CHC (CHs) =CH:.
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b. Give the structure and uses of Hexamine.
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C. Give the structure and uses of Tartaric acid.
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d. Why chloroacetic acid is more acidic than acetic acid?
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e. Write the structure and uses of Methyl Salicylate.
f. Why aliphatic amines are more basic than aromatic amines?
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g. Give the structure and uses of Amphetamine.
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h. What is Saytzeff's rule?
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1. What is the effect of base in Ez reaction?
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j. What is ozonolysis of alkene?
SECTION B
2. Attempt any two parts of the following: 2 x 10 20
a. What is isomerism? Explain structural isomerism with suitable examples.
b. Write reaction and mechanism of Aldol condensation and Benzoin condensation.
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C. What are dienes? Explain 1, 2 and 1,4 addition mechanism in conjugated dienes with
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suitable examples
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SECTION C
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3. Attempt any five parts of the following: 7x5 35


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a. Write a note on Markownikoff's orientation.


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b Write IUPAC nomenclature rules for the naming of carboxylic acids.


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Write a detailed account of SN' and SN reactions


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d. Give the chemical tests for alcohols. Give the structure and uses of glycerol.
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e. Write a note on Cannizzaro reaction.


f. Write chemical tests for amines. Give the structure and uses of ethanolamine.
g. Write a note on: i) Perkin condensation reaction ii) Inductive effect
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