a) Red Blood cells. (Erythrocytes). Struchire! Red blood cells are minute, biconcare dises, Consist of spongy cytoplasm in an elastic membrane. They have no nuclei. In their cytoplasm, a red pigment haemoglobin is present. They are made in the red bone-marrão of the short bones such as sternum, ribs and Vertebrae. Function: ) Haemoglobin contains iren in its molecule. and readily It has an affinity for oxygen Combines to form cxy-haemoglobin. This property makes it most efficient in transporting oxygen from the lungs to the tissues 2) Break down of red blood cells occurs after four months. It causes formation of bile in the liver. Bile is used in fat digestion. b) White Blood cells. (Leucocytes) round, 6) Granulocytes white blood cellshare, irregular in shape. They have lobed nucleus. They are made in the bone marrow, the lymph nodes or in the spleen Granules are present in the cytoplason, They can move by a flowing flowing action of their cytoplasm and can pass out of blood? capillaries by squeening between the cells of the capillary wall. They ingest and destroy bacteria and deadedly other pathogens by the flowing action of cytoplesom. Lymphocytes are round in structure, with smooth cell membranx Nucleus round but granules absent in the Cytoplasm Function, They seerche antibody, which acts on antigen thus it provides by flowing round, engulfing and digesting them. 3) Lymphocytes: ??? Platelets. immunity. Platelets are cell fragments budded off from special, very large cells in the red bone marrow They play an important part in the clotting action of the blood. Plasma G 7 The liquid part of the blood is called solution in water of the plasma, which is many compounds. Some of the most importent cof these compounds are sodium chloride, Sodium hydrogen carbonate, glucose, amino acids and is proteins including albumin, fibrinogen and the globulin antibodies, hormones, urea and Other nitrogenous compounds. 1007 ces In the plasma digested food carbon it dioxide, and excretory products are carried round the body. Aries ces LYMPHOCYES MEMORY CELLS [Lymphocytes are relatively small white blood cells, with a nucleus which readily, takes up the stains used to make blood small amount of cytoplasia] films and with only formed from cells in the bone marrow They are Called stem cells. [Lymphocytes are classified into two types according to the way they develop. These are B Lymphocytes and T Lymphocytes I Blymphocytes secrete antibodies into body fluids T Lymphocytes helps her to destroy antigens inside body cells, and so their role in the immune response is known cell-mediated response ] as the which XB Lymphocyte produced antibody. to be detectable in the blood. During this line the microorganism carrying the antigen set off this response able to form a large person ill. Eventually enough population to make a however, the antibodies may get the upper hand, destroying the micro-organisms and allowing the symptoms of illness to subside 0LB Lymphocyte meet an antigen for the first time. called the primary response- of the same antigen invades body on a second Occasion, a much faster response occurs which produces a much larger quantities of the appropriate antibody, and this is called a Secondary response. It happens because when the B lymphocytes divided during the primary response, some of them stopped dividing and secreting antibody and became memory cells. One Quite large numbers are of these cells each capable of secreting the antibody specific for that partienter anligen remain in the body for a long time after the first infection. They capable of responding very quickly if the Same antigen appears again. The response is often so fast and so effective that the a person is quite unaware as the micro- - organism entered in the body'] Blood Describe how the circulatory system helps to Stop bacteria entering a cut in the skin. a cut in the skin and Ans. When there is an envyme known as blood vessels are damaged, thrombe kinase is released. Thrombokinase Converts the protein prothrombin to thrombin in the presence of calcium. Thrombin then catalyses the conversion of the soluble protein fibrinogen to a meshwork of insoluble threads of fibrin. These fibrin threads entangle the blood corpuscles and the whole mass clot. The clotting of blood seals the cul- forms preventing bacteria from entering the blood stream. Q Explain, with named examples, how essential substances Carried in the blood capillaries reach the cytoplasm of the body cells Contain 2 Ans. The minute spaces between tissue cells a colourless liquid, the tissue fluid. This tissue fluid carries substances in solution between the body cells and the blood capillaries, Oxygen is carried in the red blood cells as Oxyhemoglobin. When blood passes through oxygen- pook tissues, cxygen is liberated. It then diffuses out of the blood capillary wall. Dissolved food substances also diffuse out of the thin walls of the blood capillaries into the tissue fluid. From there, these substances diffuse into the cytoplasm of the cells. IS Q. Describe and explain the flow of blood through the heart from the time that it arrives at vena cava to the time that it leaves at aorta. Ans: Deoxygenated blood from the head, neck and arms is returned to the right atrium by the superior vena cava. When the right atrium Contracts, blood flows in to the right ventricle via the tricuspid valve which separates the atrium from the ventride and prevents the back flow of blood from the ventride to the atrium. Blood leaves the right ventricle when it contracts by the pulmonary arch which subsequently divides into Huot two pulmonary arteries, one to each lung. Backflow of blood into the right ventricle is prevented by semi-lunar valves in the pulmonary arch. Oxygenated blood from the lungs are returned to the left atrium by the pulmonary veins when the left atrium contracts, blood is forced into the left ventricle via the bicuspid valve which prevents the back flow of blood into the atrium. When the left ventricle contracts, the blood flows into the aorta and is then distributed to all parts of the body except the lungs. The aorta also contains semi-lunare Valves to prevent the back flow of blood into the left ventricle. Q. a Bleed. Describe how o molecule of digested food from the gut enters the blood stream. Ans. A molecule of digested feed e.g. glucose which is broken down from carbohydrates in the mouth and stomach pass along the gut by peristalsis until they reach the small intestine. The walls of the intestine are made up of numerous finger-like projections called villi which project into the intestinal cavity. The villi are rich supplied with blood and lymphatic vessels to carry away the food substances. The glucose molecule is absorbed by the villi and the glucose passes across the walls of the blood vessels and into the blood stream. Q. Describe the pathway by which the glucose molecule eventually reaches calls in the hand. Ans. The blood leaving the small intestine with glucose molecule enters the hepatic portal vein. This pauses through the liver and via the hepatic vein and ! posterior vena cava, the deoxygenated blood reaches the heart. The heart pumps this blood to the lungs which then, after that, flows back to the heart. Now the blood with, the glucose is then pumped out of the heart via the north. The aort branches into the sub-clarian artery and the dorsal aorta. The arm, // 67401 weed cel being fore-limb is supplied with blood from m heart via the sub-clavian artery. As the blood passes" the tissues in the hand, the molecule of food i.e. glucase passes out from the blood capillaries and to the calls of the hand. Q. What is meant by a double circulation? Ans. In double circulation, blood passes through the heart twice: from the main circulation of the body to the heart, then to the lungs and back to the heart again before the blood is pumped into the main circulation. 6. How do the tive parts afada circulation differ from One another? Ans. The pulmonary circulation links the lungs to the heart. Pulmonary arteries carry the blood to the lungs; oxygenated blood is returned to the heart by the pulmonary veins. Systemic circulation is the main circulation. Oxygenated blood is distributed to all parts of the body, and veins carry the blood from all parts of the body back to the heart. Vena cara Semilunan valve Right atrium Tricuspid valve Right-ventricle Con Pulmonary artery 402 -Aohla Wall -Pulmonary vein B. Left ventricle -Left atrium -Bicuspid valve ·Tendon Left ventricle •Cardige muscle. Section of Heart- Lumen. Elastic muscle fibre Section of artery Non elastic muscle fibre. Wall section of vein Sectional Blood capillary (7 47