The relations of power and privilege between Colombian peasant farmers and cartel bosses described are characterized by the complexity of socioeconomic factors, access to resources, and health outcomes. The core of this matter is the cultivation of coca, a plant which is mainly grown in regions having deficient economic opportunities and poor educational access. For many farmers, still in the marginalized spots, cultivating coca is a pragmatic choice supported by the lack of other opportunities for generating income. The social determinants of health, as stated by the CDC and WHO, bring to the fore the vital role of factors like economic stability, education, and environment in neighborhoods in shaping the health and well-being of individuals and communities. It is known in Colombia that the social gradient of health is very clear, and those in the lower socio-economic bracket are disproportionally affected by inequities in health. This gradient mimics the drug misuse and abuse realm where socioeconomic disparities are aggravated, thus resulting in vulnerabilities and negative health outcomes. While the cartel capos enrich themselves and others engage in the illicit drug trade, peasants (farmers) have difficulty accessing health services, suffer from severe economic instability, and are victims of educational disparities. The theory of social determinants of health explains how these structural inequalities continue to trigger the circle of poverty and health disparity making the challenges faced by the vulnerable populations appear even worse. Additionally, efforts to suppress coca bush by using defoliants have indirectly worsened societal disparities and health inequalities. The policy goal of such efforts being to eradicate drug production would have counterproductive impacts on marginalized communities and peasant farmers who depend on coca cultivation for their survival. The unceasing operation of the underground drug trade illustrates the complicated interrelationship of economic motives, environmental factors, and social dynamics that figure out drug production and distribution patterns. In order to tackle the matter of social determinants of health and drug related issues, interventions will need to be holistic and have a focus on structural inequalities as underlying factors. This is achieved not only through tackling the drug supply chains but also by addressing the underlying causes such as poverty, illiteracy, and limited access to health care. If these upstream determinants are tackled, policymakers and practitioners will be able to produce more equal health outcomes and reduce the negative consequences of drug misuse and abuse among the marginalized. The process of reaching health equity depends on a multidimensional comprehension of the social, economic and environmental issues influencing individual and community health, especially in contexts where there are social and economic inequalities and structural inequities. Works Cited Wright, Tashelle. “This History of Cocaine and Amphetamines.” Salt Lake Community College, Salt Lake City, UT. Wright, Tashelle. “Social Determinants of Health.” Salt Lake Community College, Salt Lake City, UT.