Professional Documents
Culture Documents
yohimbine, was approved for use in dogs years ago vaporizers, vaporizers filled with the wrong agent,
to reverse the effects of xylazine. Atepamezole is a or overfilled vaporizers are common problems.
better antagonist for dexmedetomidine and is often Delivery of nitrous oxide in combination with too
effective by titration of reduced doses (approved for little oxygen should be carefully avoided and is not
SC administration) to secure prompt recovery with always prevented by “fail-safe” systems incorporated
less excitement and stress than would result from the in modern machines.
administration of a higher dose.
Kinked or plugged endotracheal tubes cause respira-
Nonspecific partial reversal of anesthetic depression tory obstruction. Improper cuff inflation can result
is possible by administration of the respiratory stim- in obstruction, tracheal injury, or allow for aspira-
ulant doxapram, but this is usually not an appropri- tion pneumonitis. Improper placement of endotra-
ate replacement for positive pressure ventilation and cheal tubes is very common, even in species that are
other supportive care. Although the net effect can easily intubated. Correct placement should always be
be life saving, nonspecific reversal has been associ- verified.
ated with residual undesirable effects related to CNS
stimulation and even deaths! Other stimulants have An inability to adequately fill the rebreathing bag or
been advocated to correct excessive effects of vari- to provide positive pressure ventilation by squeez-
ous anesthetics, but the benefits are usually very ing the bag often indicates major leaks or discon-
limited. nections. These can result in a failure to deliver
anesthetics and oxygen and substantially contribute
Anesthetics administered by an incorrect route can to anesthetic gas pollution of the veterinary hospi-
have very adverse effects. The extravascular injection tal. Stuck valves in the anesthesia machine or circuit
of barbiturates can cause severe irritation and slough- can cause difficulty in ventilation. Inappropriate
ing of surrounding tissue. Extravasation should be rebreathing of exhaled gases or the accumulation of
treated immediately with generous infiltration of excessive pressure results. Patients that consistently
the site with lidocaine and saline, followed by warm seem to be too deep or too light may indicate that
compresses. Errors in the administration of anesthet- the vaporizer is out of calibration due to wear and
ics also include the misidentification of drugs and tear, there is accumulation of deposits within the
accidental use of the wrong medication. vaporizer, or other factors. These common problems
emphasize the importance of regular inspection and
Equipment Problems maintenance of equipment.
Among the most serious anesthetic complications
is the failure to deliver oxygen to the patient. This Electrical problems with monitoring or support-
can be caused by respiratory obstruction or misused ive equipment risk injury to personnel as well as to
or defective anesthetic equipment. Empty tanks or patients. Inadequately grounded or protected equip-
misconnected gas lines and breathing circuits prevent ment can cause electrical burns, electrocution, or
the delivery of oxygen. Such problems must be recog- fires. Unsafe or substandard equipment should be
nized and corrected immediately. Empty anesthetic repaired or replaced.
3
Crisis Management: How to Handle Emergencies and Complications
Vasodilatation is a very common side effect of many Ventricular tachycardia should be treated with intra-
anesthetic drugs. The tranquilizer acepromazine is a venous bolus injection of 2% lidocaine at a dose of
hypotensive drug, particularly at higher doses. The 1, 2, or 3 cc in small-, medium-, or large-size dogs
volatile anesthetics also cause significant vasodilata- respectively. This rule of thumb will allow for imme-
tion. Most anesthetics also are potent cardiac depres- diate therapy without an accurate dose calculation,
sants, again particularly at higher doses. Hypotension which could contribute to a life-threatening delay. It
under anesthesia is therefore most appropriately has been recommended that propranolol is the drug
managed by reduction of anesthetics and fluid of choice for treating ventricular arrhythmias in cats.
administration as primary management. Lidocaine is also effective in cats. Total dose limita-
tion is more important in cats due to their smaller
Tachycardia body size and blood volume.
Heart rates above 180/min in dogs and 200/min in
cats are associated with decreased efficiency and Success in emergency management of ventricular
increased workload. Tachycardia can be due to fear, arrhythmias is evaluated by continuous ECG moni-
pain, inadequate anesthetic depth, pre-anesthetic toring. Bolus injections of lidocaine can be repeated
excitement, or a rough induction of anesthesia. to a total accumulated dose of about 10 mg/kg without
Hypotension causes a compensatory tachycardia. significant risk of overdose. When two or three injec-
These causes of supra-ventricular tachycardia should tions are required over a period of 15–20 minutes, it
be recognized and treated. is necessary to convert to a continuous IV infusion of
lidocaine at 30–80 micrograms/kg/min. Refractory
Compensatory tachycardia in response to hypovole- arrhythmias may require conversion to therapy based
mia and hypotension results in decreased coronary on alternative antiarrhythmic medication.
artery blood flow and increased myocardial work-
load. If other conditions contribute to hypoxia there Delayed Recovery
is significant risk of development of more serious Delayed recovery from anesthesia is managed by
arrhythmias. Fluid therapy for hypovolemia, adjust- recognition of differential causes and a rule-out of
5
Crisis Management: How to Handle Emergencies and Complications
individual possibilities. A systematic approach to field resistance electric heating systems are very
potential causes will provide for balanced care, with effective and can be much less costly to use.
correction of often multiple factors such as hypother-
mia, inadequate fluid support, reduced metabolism Warm water bottles or surgical gloves filled with
or clearance of drugs, and debilitation associated warm water have been shown to be rather inef-
with the stress of anesthesia and surgical trauma. fective in raising the body temperature of hypo-
Deterioration due to a hypoxic episode must be thermic patients and at the same time constitute a
considered. significant risk of causing thermal burns at the site
of contact. Circulating warm water blankets are a
Hypothermia much better alternative to warm water bottles or
Hypothermia is among the most common of gloves, but these are of limited efficacy in rewarm-
anesthetic complications. Body heat is lost with ing hypothermic patients. Forced warm air heating
preparation of the surgical site, contact with systems are more effective than circulating warm-
cool surfaces such as surgical tables, breathing of water blankets and can also be used to cool hyper-
dry anesthetic gases, and evaporation from the thermic patients when set to deliver unheated
airways and the surgical field. Moderate hypo- ambient air. Proper use of forced air systems must
thermia is a frequent problem, even with atten- include some type of dispersive blankets to envelop
tion to each of these factors. Body temperatures the patient in warmed air and avoid hot spots by
down to approximately 92°F increase oxygen distributing the warmed air. The dispersive blan-
and energy requirements during recovery, but kets and the high consumption of electricity both
most patients can tolerate this level of hypother- increase the cost of use of the forced warm air
mia. More extreme hypothermia causes delayed systems.
recovery, reduces tissue perfusion, and increases
morbidity and mortality. Other Complications
Many other complications and emergencies can
The risks of thermal injury are so great with older occur during or be associated with anesthesia. These
consumer-style electric heating pads that their use include anaphylactic-like reactions, hyperthermia,
in anesthetized, sedated, or depressed (many criti- biochemical imbalances, gastroesophageal reflux,
cally ill) patients is considered extremely hazard- regurgitation, vomiting, aspiration, and many surgi-
ous. A very different dispersed field or amorphous cal complications such as hemorrhage and pneu-
resistance electrical heating blanket to avoid ther- mothorax. Avoidance of complications and effective
mal injury and safely warm the patient is now avail- management of emergencies requires continued vigi-
able from at least two sources. These new dispersed lance and immediate appropriate action.
6
What Really Works in Anesthetic and
Perioperative Care
RALPH HARVEY, DVM, MS, DACVA
In recent years, anesthesia has become better and North American colleges of veterinary medicine.
safer, in that we are now able to provide successful Through the North American Veterinary Technician
anesthetic management for patients who would not Association, licensed veterinary technicians may
have had a reasonable chance a few years ago. In many now pursue Veterinary Technician Specialist certi-
cases, these are even managed as outpatients, quickly fication in anesthesia with advanced training and
returned to their owners in full recovery. Our choice skills in veterinary anesthesia and membership in the
of anesthetic drugs has greatly expanded, and safer Association of Veterinary Technician Anesthetists.
anesthetic agents are indeed responsible for much of
the improvement noted. The use of more sophisti- Monitoring and Attention to Detail
cated monitoring and better physiologic support has In addition to veterinarians, well-trained technicians
become widespread, with continued rapid growth continuously evaluate the patient throughout anes-
apparent in this area. In spite of increased owner thesia. Awareness of the ever-changing condition of
expectations and the fact that veterinarians now have the anesthetized patient is a shared responsibility that
sicker patients presenting with concurrent diseases, can only be shared effectively and safely when the
injuries, or debilitation, we can increasingly manage medical team works together. We intend to remain
our patients successfully with the improvements in aware of even subtle changes in patient status under
anesthesia and related perioperative care. anesthesia. We must always recognize that challenges
to the welfare of our patients come not only from
Better Training and Ongoing Training their underlying illness or injury, but also as unde-
This paper on veterinary anesthesia helps to provide sired effects that even the best anesthetic care may
an update on current and developing methods. present.
Continuing education seminars and numerous
other contemporary publications attempt to further Modern monitoring equipment is increasingly avail-
these same goals. The education of veterinar- able at reasonable cost for veterinary use. We no longer
ians and veterinary technicians now includes rather need to rely upon out-of-date, poorly serviced, unsafe,
extensive attention to anesthesia and related topics. and inappropriate equipment that has been discarded
Veterinarians with advanced training in anesthesia from human patient use. Fortunately, however, there
and board certification by the American College of is good-quality equipment still available from the
Veterinary Anesthesiologists are now involved in human patient market. Increasingly, that equipment
the training of new veterinary students at almost all now can be found with good warranty protection,
Adapted from AAHA/OVMA Toronto 2011 Proceedings © 2011 American Animal Hospital Association. All rights reserved. 7
What Really Works in Anesthetic and Perioperative Care
recent service records, and, importantly, with design able inhalant, sevoflurane, can be used to provide for a
and function capabilities well suited to veterinary remarkably rapid yet smooth induction and recovery
patient needs. There is also good-quality equipment from anesthesia, and can provide for a rapid change in
available specifically for the veterinary patient. Medical the level of anesthesia as needed. Appropriate use of
equipment sold exclusively for veterinary use does not these new agents requires skill and knowledge and will
receive the degree of oversight and approval required be addressed more fully. All anesthetics have a limited
for human-use equipment. In spite of this, there is therapeutic index, or margin of safety. All can depress
very good veterinary-specific medical equipment. The vital functions, and inappropriate use can result in
demands of veterinarians, and of animal owners, for loss of life. It is useful to remember the old guideline:
improved anesthetic delivery, monitoring, and support “There are no safe anesthetics, just safe anesthetists.”
has fueled the growth of this industry.
While we enjoy a wealth of new options and opportu-
No longer is the application of relatively advanced nities in veterinary anesthesia, we must make changes
monitoring equipment and anesthesia machines in our anesthetic strategies carefully, recognizing
limited to academic institutions or referral practices that experience is necessary to identify any abnor-
with heavy surgical caseloads. Monitoring of electro- mal responses from those that should be expected.
cardiogram, temperature, blood pressure, and pulse Careful and conservative use of any new anesthetic
oximetry are rapidly becoming more routine, even in or technique is crucial. “Nobody likes an adventurous
general veterinary practices. Airway monitoring of anesthetist!”
carbon dioxide and anesthetic gases in the breathing
circuit is also becoming more popular. Proper use of Individualized Anesthetic Care
these technologies requires a good working knowl- Much more important than the choice of which
edge of the normal values, the significance of devia- specific anesthetic drugs or equipment we use,
tions, and an understanding of appropriate manage- however, is the manner in which we select them and
ment options. the skill and care with which they are used in our
patients. Best use of various options requires an indi-
New Options in Anesthetics vidualized approach to anesthetic management. In
Through the use of a good variety of injectable and treating infectious diseases, veterinarians wouldn’t
inhalant anesthetics, great anesthetic safety and choose the same antibiotic for every patient or condi-
convenience is possible for our patients. Remarkable tion encountered. Similarly, the best choice among
improvements have developed in outpatient anesthe- options in anesthetic care requires recognition of
sia. The recent popularity of several injectable anes- individual needs and individual risk factors, which
thetics, most popularly propofol, has greatly improved vary widely among veterinary patients. We recognize
our options. Product shortages have resulted from the breed sensitivities and relative contraindications in
removal of defective generic products, but we can the choice of anesthetics. For many years, breed asso-
manage this temporary supply-and-demand issue. ciations have provided warnings based on anecdotal
Isoflurane has been the strongly predominant inhal- reports. With continued research, some of these have
ant anesthetic for several years. The more newly avail- been or will be substantiated. Others perhaps will
8
What Really Works in Anesthetic and Perioperative Care
be refuted. In the absence of clarifying data, caution the family for more years. With an aging pet popula-
dictates selection and use of the best anesthetics from tion, and with keen interest in keeping pets as very
among the many choices available. functional members of the family group, we have the
opportunity to care for many more geriatric patients.
Patient differences that are important in anesthetic These much-loved pets often receive more extensive
care are obviously not only those that relate to species, pre-anesthetic evaluations, which help to identify
breed, and age differences. As a simple example, marginal reserve function and any subclinical organ
patients undergoing elective surgery or those who are disease or dysfunction. Geriatric patients have dramat-
traumatically injured both need analgesic therapy. ically reduced requirements for many anesthetics and
Opioid analgesics, for instance, have varying efficacy could be overdosed at standard recommended drug
and duration of action. The range of choices allows doses. Armed with this information, the veterinarian
for brief, mild analgesia such as for an outpatient can individualize anesthetic care to minimize the risks
neuter, all the way to profound analgesia for the care of complications. Typical of this patient type would
of a substantially traumatized animal. be the older dog presented for routine dental care.
Through our improved care, we can extend not only
Pre-anesthetic Evaluation and the lifespan, but also the “healthspan” of these animals.
Screening
Better anesthetic care also includes a more thorough Outpatient Anesthesia
pre-anesthetic evaluation, which can fit nicely into a As human patients, we expect to have most mini-
comprehensive approach of well-patient care and the mally invasive medical procedures, and even many
work-up of the non-elective patient. Pre-anesthetic substantial surgeries, conducted on an outpatient or
evaluations should be tailored to the needs of the same-day basis. Reduced hospital costs are not the
patient. For example, the pre-anesthetic evaluation only concern driving this change in human patient
of a diabetic patient would include blood glucose care. Everyone is happier and can return to daily
determination(s) to help guide physiologic support routines more quickly with shorter hospital stays.
as a part of the anesthetic care. Basic physical findings This applies to veterinary medicine as well. Better
may lead to more extensive evaluations. For example, if anesthetic care is a major component of this change.
a heart murmur is detected in a young cat, an echocar- Clients personally experience it in their own medical
diogram may be performed to rule out cardiomyopa- care from the perspective of patients, and now they
thy before subjecting the animal to the stresses of anes- expect it in the veterinary care we deliver for their
thesia. Not all patients need the same level or intensity pets as well. Reliable, fast, and smooth recovery from
of pre-anesthetic evaluation or screening. Matching anesthesia is a wonderful feature of many of the more
the process to the patient becomes cost effective for the modern anesthetic methods. While every patient
pet owner as well as for the practice owner. differs, we’ve come to expect more and more of our
patients to bounce back quickly.
Geriatric Patient Care
It is fortunate that the improved role of pets in our Prior Preparation Prevents Problems
society has in various ways kept animals as a part of Readiness includes anticipation of contingencies and
9
What Really Works in Anesthetic and Perioperative Care
and the high consumption of electricity both increase care is indeed moving forward. Many animal owners
the cost of use of the forced warm air systems. assume that the veterinary anesthetic care and pain
management their animals receive are already at a very
Summary high level of sophistication, perhaps even comparable
There seems to be little upper limit to the sophisti- to that afforded to human patients. Our obligation to
cation of medical care demanded by the pet-owning do the best we can for our patients and for our clients
public. Improvements in all areas of veterinary medi- requires that we move forward and maintain very
cine are being rapidly embraced. The standard of high standards in providing anesthesia and analgesia.
11