Lesson 4 | IV Bolus Administration, Multiple Drug Administration, & Steady-State Average Concentrations

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4-14. A, B, C. Incorrect answers Then, use the following to calculate the

D. CORRECT ANSWER. To answer this trough plasma concentration:
question, K must first be calculated: −1
C trough = C peak × e − Kt = 40 mg/L × e −0.21hr × 8 hr

K = (lnC 5 hr − lnC peak ) / 5 = −0.206 hr −1 = 35 mg/L × 0.186 = 7.45 mg/L