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10 1108 - Eemcs 11 2021 0370
10 1108 - Eemcs 11 2021 0370
Covid-19 vaccine
Sunny Vijay Arora and Malay Krishna
The vaccine industry has sacrificed billions of dollars of profits . . . in providing this vaccine at this Sunny Vijay Arora is based
price – Adar Poonawalla, CEO of Serum, April, 2021 (Inamdar, 2021). at the Department of
Marketing, S. P. Jain
Institute of Management
Introduction and Research, Mumbai,
India. Malay Krishna is
A difficult pricing decision confronted Adar Poonawalla, the 40-year old CEO of the world’s based at the Department of
largest vaccine maker – Serum Institute of India (Serum). It was the 20th of April in 2021, Strategy and Innovation,
and Serum and one other Indian vaccine maker had been negotiating prices for Covid-19 S. P. Jain Institute of
(Covid) vaccines with the Government of India (GOI) (Mukherjee, 2021). This was not the Management and
first time that Poonawalla had come to the negotiation table on pricing its Covid vaccine Research, Mumbai, India.
named Covishield – Serum’s brand name for the Oxford-AstraZeneca vaccine (Arora &
Miglani, 2021). Serum had been India’s first vaccine maker to receive emergency use
authorization for its Covid vaccine and was the first to deliver 10 million doses to the GOI, by
the end of January (Rajagopal & Bureau, 2021). Serum’s initial batch of vaccines had been
priced at INR 250 per dose (Kalra, 2021). Since then, Serum has supplied the GOI with
about 60 million doses a month, at an average price of INR 150 (equivalent to US$2) per
dose (Kapur, 2021).
What was different in April was that the GOI had confirmed a pricing move that had long been
hinted: it would pay for only 50% of vaccine supplies in India (Mathew, 2021). Called an “open
market” pricing system, beginning the first of May 2021, 50% of vaccine production in
the country would be open for procurement by state governments and private hospitals.
One rationale for this move was that public health care was part of both union and state
government charters in the Constitution of India. The announcement had created a challenge
as well as an opportunity for Serum. The challenge was in the complexity: as India was The authors wish to thank
SPJIMR’s Office of Research &
comprised of 28 states, how many different price points should Serum set? Yet, this was also Innovation, which provided
an opportunity, as Poonawalla had maintained that the INR 150 per dose pricing was not seed funding for this case
study. We also wish to thank
sustainable and had previously approached the prime minister for a doubling of the price Mr Saksham Rihani and
(Sahu, 2021). In addition to the pricing for states, Serum also had to decide on the Covishield Mr Harsh Upadhyay who
provided assistance in
pricing for private hospitals. The private hospitals could charge a higher price and, gathering, collating and
consequently, would be willing to bear a higher cost of procuring the vaccine. But Poonawalla analysing the information for
this case.
also had to consider the ground realities in late April: soaring counts of Covid cases and
Disclaimer. This case is written
hospitalizations as a second wave of Covid hit India hard (Jamkhandikar, 2021). solely for educational purposes
and is not intended to represent
successful or unsuccessful
Background of serum and the Poonawalla family managerial decision-making.
The authors may have
disguised names; financial and
In 1966, Cyrus Poonawalla, father of Adar Poonawalla, founded the Serum Institute of India other recognizable information
Pvt. Ltd. and formally launched the business of producing vaccines and antitoxins for to protect confidentiality.
DOI 10.1108/EEMCS-11-2021-0370 VOL. 13 NO. 1 2023, pp. 1-33, © Emerald Publishing Limited, ISSN 2045-0621 j EMERALD EMERGING MARKETS CASE STUDIES j PAGE 1
tetanus (Serum Institute of India, 2014). The decision to establish the vaccine business had
come about through a curious mix of heritage and circumstance. The Poonawallas ancestry
could be traced to a migrant who, in the mid-19th century, settled in Pune, about 90 miles
from Mumbai, the financial capital of India. He started spending time as a “billiard marker”
at a British officer’s club and used his connections with the British colonial rulers of India to
start a construction business. He grew the business many times over and owned so much
land that he received the moniker, “Poonawalla,” which meant “the guy from Poona,” Poona
being the erstwhile name for the city of Pune. Poonawalla’s descendants divided the
inheritance among themselves. One of the inheritors, Soli Poonawalla – Adar’s grandfather –
received a house and 40 acres of undeveloped land, which he converted into a stud farm to
breed racehorses. Over time, the Poonawalla Stud Farms became India’s most successful
breeder of racehorses. In 1947, India became independent of British rule, and the kings’
sport of horseracing started losing popular appeal. Soli’s son Cyrus joined his father in
running the business but quickly realized that the business demanded diversification
(Kanwal, 2019).
Cyrus soon found an opportunity close to home. In the 1960s, the Poonawalla’s family
donated some of their retired racehorses to a government lab, which used the horses to
produce anti-venom and tetanus antitoxin to neutralize snakebites and tetanus (Frayer,
2021). To produce such medical substances, horses were first injected with small quantities
of venom, bacteria or other toxins so that their bodies developed antibodies and antitoxins.
Those could then be harvested from the fluid part of their blood, also known as serum, and
then refined into treatments for humans. In 1966, a snake bit one of the Poonawallas’
horses, and they requested the government lab for anti-venom serum. The lab needed
government approval, which took four days, and by then, the horse had died. This incident
motivated Cyrus to consider making the serums in-house. At about the same time, India’s
economy was recovering after recent wars with China and Pakistan. Among other essential
supplies, India’s large population required low-cost vaccines and antitoxins. Thus, Cyrus
began producing vaccines using the antibodies from retired racehorse serum, and the
Serum Institute came into being (Altstedter, 2020).
This move coincided with the rapid international development of vaccines. In 1971, Dr
Maurice Hilleman created the combined vaccine shot of measles–mumps–rubella while
working at Merck & Co. (Tulchinsky, 2018). Health efforts to eliminate polio and smallpox
globally were also underway (Bhattacharya & Dasgupta, 2011). In India, the GOI had
sponsored some nationalized institutes to produce vaccines, but such efforts tended to be
very slow. In contrast, Serum’s management team was agile, acquired advanced
equipment and know-how and operated at lower costs while maintaining a low price for their
vaccines and other products. Soon, Serum won contracts from several Indian states and the
Union GOI for its vaccines. Serum continued to reinvest in its facilities by importing
equipment from the USA and Europe, as well as adding more product lines. Serum also
began exporting its vaccines, and by 2000, had a customer base spanning 35 countries.
Serum maintained a market focus on supplying affordable vaccines to lower income and
middle-income countries (Kanwal, 2019). UNICEF (United Nations Children’s Fund), a
United Nations body dedicated to providing humanitarian aid to children worldwide, often
purchases vaccines for target market countries. Another organization that placed such
orders with Serum was GAVI (the Global Alliance for Vaccines and Immunizations), in
association with the Bill & Melinda Gates Foundation. Serum was familiar with the needs of
such target market countries, as conditions were similar to Serum’s home country of India.
This market niche had less competition as major Western vaccine manufacturers focused
on producing more complex, high-margin vaccines for high-income countries. Reduced
competition led to rapid sales growth for Serum, which in turn led to increases in capacity.
Serum funded this expansion from its own retained earnings and bank financing; however, it
chose not to raise funds from the capital markets for fears of diluting its control and
Through March of 2021, high vaccine hesitancy prevailed among many frontline health-care
workers; many refused the Covaxin shot, with a little over half of the target population
coming forward for vaccination (Kay, 2021).
Indian hospitals
In February of 2021, the GOI announced plans to include nearly 24,000 private hospitals as
Covid vaccination centers to augment the 10,000 government facilities already pressed into
service (Sharma, 2021a). At government-run public hospitals, the Covid vaccine was
delivered free to all eligible citizens, while at private hospitals the price to consumers was
capped at INR 250, which was comprised of INR 150 for vaccine procurement from the GOI
and INR 100 for the vaccine delivery fee (Sharma, 2021b). However, in mid-April, the
likelihood of new government guidelines introduced uncertainty for private hospital pricing
going forward. As the COO of Fortis, a major Indian hospital chain, remarked in April, “We
are waiting for the guidelines which are expected in a week. But our understanding is that
private hospitals would need to procure directly from the vaccine-maker” (Sharma &
Thacker, 2021).
Also, by mid-April, the delta variant of the Covid virus caused a massive surge of infections
in India, with a concomitant quadrupling in demand for vaccines, as hospitals saw long
lines of people hoping to get doses (Bellman & Agarwal, 2021). In Mumbai, the financial
capital of India, 25 of the 71 private hospitals that were designated vaccination centers had
run out of vaccine stock; and vaccine supplies across hospitals (120 including public
hospitals) were down to just one day (Staff Writer, 2021). Hospitals across the country were
also under pressure because of increasing rates of Covid-related hospitalization and
shortages of critical resources such as ICU beds and medical oxygen (ET Bureau, 2021).
Serum’s capital investments in Covid vaccine production were significant: to upgrade its
production capacity, Serum had imported stainless steel vats from Europe worth about INR
300m or US$4m each for producing the Covishield vaccine (Frayer, 2021). In addition, its
refrigerated warehouse now stocked 70 million vials of Covishield at any given time.
Poonawalla estimated that the direct and indirect expenses required to develop and
produce Covid vaccines was INR 11.3bn or US$150m (Mukherjee, 2020a).
Notes
1. For ease of calculation and as a reasonable approximation, one can assume that half of India’s
entire population is likely to be fully vaccinated by the end of 2021.
2. Total Indian population in 2021 was 1,393,409,038 [www.macrotrends.net/countries/IND/india/
population-growth-rate#::text=The%20current%20population%20of%20India,a%200.99%25%
20increase%20from%202019].
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Table E1
Financial parametera Serumb Pfizerc AstraZenecad J&Je Moderna
Table E2
State Population Health expenditure per person (INR)
Table E3
Percentage of Earn annual income equal to or more Monthly income Monthly income per
people than (INR) (INR) person (INR)
Corresponding author
Malay Krishna can be contacted at: malay.krishna@spjimr.org