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Reference:
Smith, J., Johnson, A., & Brown, K. (2020). Ophthalmic Disorders: A Comprehensive Guide. Springer.
QUESTION ONE.
Blepharoptosis, more commonly known as “ptosis,” is an abnormal drooping of the upper eyelid
with the eye in primary gaze(). This drooping can affect one or both eyes and based on the time
of appearance, it is broadly classified as either congenital (present at or shortly following birth)
or acquired (appearing later in life).
a. Presurgical considerations that will determine whether or not patient should undergo ptosis
surgery include;
The degree of ptosis: the degree of ptosis determines the severity of ptosis and how it affects
the vision of the patient. This can be determined by measuring the vertical heights of palpebral
fissures on the two sides (in unilateral ptosis) or measuring the amount of cornea covered by the
upper eyelids and subtracting 2mm (in bilateral ptosis). The degree of ptosis is usually graded as
mild (< 2mm), moderate (2 – 3.5 mm) and severe (> 4 mm).
Levator Function: the function of the levator muscle responsible for lifting the eyelids is
measured. There are methods of measuring the levator function which includes the Berke’s
method and the marginal limbal distance (MLD). In Berke’s method, the amount of upper eyelid
excursion is measured with a ruler when the function of the frontalis muscle is blocked. MLD is
usually used by surgeons to measure the levator function in order to determine the amount of
levator muscle to resect. The amount of levator function present will determine the appropriate
surgical interventions and its success rate for the patient. Levator function is graded as normal
(15 mm), good (≥ 8 mm), fair (5-7 mm) and poor (≤ 4 mm).
Visual function of the patient: Droopy eyelids can lead to obstruction of vision in the patient. In
cases where ptosis tends to interfere with normal vision or cause difficulties in daily activities,
such patients must undergo surgery to correct this impairment. Hence the visual function of the
patient will determine whether the patient needs surgery or otherwise.
AGE Age is a major factor when thinking about ptosis surgery, especially for younger
people. Congenital ptosis, which appears at birth or early infancy, may require early
surgical intervention to ensure normal visual development and prevent amblyopia. Age-
related changes in the elasticity and structure of the eyelids can affect the surgical
technique chosen as well as the expected results in adults (Pham, 2018).
Ggeneral health: Assessing the general health of a patient allows surgeons to assess surgical
risk, tailor perioperative management strategies, optimize anesthesia plans, anticipate
potential complications, and optimize postoperative care to achieve optimal outcomes
and promote patient safety and well-being. Patients with systemic diseases such as
hypertension and diabetes may have impaired wound healing and increased
susceptibility to infections affecting the general outcome of ptosis surgery.
Ptosis affecting vision in children may cause amblyopia making surgery necessary in such instances.
However, in patients where amblyopia as already set in, surgery may not be of much benefit unless for
cosmetic purposes.
b. Surgical procedures for ptosis management usually depend on the severity of ptosis and
degree of levator function present. Two surgical techniques that are done to remedy ptosis
include;
Fasanella- Servat operation and Frontalis sling operation.
The Fasanella- Servat procedure is indicated in patients with mild degree of ptosis and good
levator function. In this procedure, the upper eyelid is everted and an excision of the
tarsoconjunctiva, Muller’s muscle and the levator palpebrae superioris muscle is made. The
muscles are resected by cutting a specific amount of muscle tissues depending on the
degree of ptosis. In most cases about 3mm of tarsoconjunctiva and Muller’s muscle is
resected.
However, Frontalis sling operation also known as brow suspension surgery is commonly
indicated in patients having severe ptosis with poor or no levator muscle function (levator
function of 4mm or less). In this technique, it connects the eyelid to the brow with a sling
material and utilizes the power of the frontalis muscle to elevate the poorly functioning
eyelid. It is done by creating a sling from the frontalis muscle to the eyelid, directly
suspending the eyelid to the brow. It can also be used to create eyelid crease usually in
congenital ptosis. The materials used as sling may be autogenous grafts, allogenic (banked
fascia lata) or synthetic grafts materials (polypropylene suture, silicone, nylon suture, Gore-
Tex). The most common autogenous materials used include fascia lata, palmaris longus
tendon and temporal fascia. The fascia lata is considered the gold standard procedure for
congenital ptosis because it has a long-lasting effect for eyelid elevation and low
complication rate. Through it requires a second surgical site for harvesting the fascia, it has
been successfully used in children younger than 3 years. Synthetic grafts materials have a
higher rate of recurrence as well as higher risk of granuloma formation, infection, extrusion
and breakage after trauma. There are various suture designs which include; single triangle,
double triangle, single rhomboid, double rhomboid, single pentagon and double pentagon.
Of these suture designs, the single rhomboid is considered appropriate for children as it
prevent postoperative bending of the eyelids.
The considerations that will determine the choice of either procedure in ptosis surgery
include;
Severity of ptosis: Fasanella- Servat will be the appropriate choice for patients with
mild degree of ptosis while Frontalis sling will be the appropriate choice for patients
with severe ptosis.
Levator function (upper lid excursion): Fasanella- Servat will be the appropriate
choice o surgery for patients with good levator muscle function while Frontalis sling
will be the appropriate choice of surgery for patients with poor no levator function.
It is measured as the distance from the upper eyelid margin in downgaze to up gaze
with frontalis muscle function neutralized
Recovery time after ptosis surgery: Fasanella- Servat tends to have a shorter
recovery time compared to the others.
Potential risks and complications involved in each ptosis surgery: Levator
advancement surgery tends to have the highest rate of complications. Frontalis sling
tend to have a higher recurrence rate of ptosis depending on the sling material used
i.e., allogenic materials.
Age of patient and aesthetic goals.
c. Key points of interest when conducting a post- op assessment of a ptosis patient include;
Visual function of patient: this is one of the key points of interest in post- op assessment.
This is done to ensure the probable visual obstruction caused by ptosis has been
removed and the patient can comfortably see. This is also assessment to ensure that,
nothing tempered with the vision of the patient.
Eyelid symmetry: Eyelid symmetry and is assessment as part of post- op management to
ensure that both eyelids have a balance appearance.
Eyelid position and contour: This is one of the key points that form part of post- op
management to ensure there was no overcorrection or under correction of the ptosis or
the adequate correction was made.
Eyelid function: One of the major key points when conducting post- op assessment is the
eyelid function. This is done to ensure the lids are functioning properly in terms of
movement, closure and blink reflex.
Complications: The surgical site and the eye as a whole is assessment for complication of
ptosis surgery such as overcorrection, under correction, ectropion, entropion,
conjunctival prolapse or the presence of any infections. This is done so that any
complication can be treated at its early stage before it worsens.
Routine instructions:
QUESTION TWO.
a. LASIK (Laser- assisted in Situ Keratomileusis) is a type of laser refractive surgery which reshapes
the cornea stroma by using excimer laser to ablate or remove tissues to a precise depth without
causing much disruption to the surrounding area. This surgery is split into two phases where; a
femtosecond or picosecond laser microkeratome is used to create a thin flap, then another laser
is used to reshape the cornea. The superficial flap is made to assess the layers of the cornea and
this aids in reshaping the cornea to correct the imperfections of its curvature. The superficial flap
created remains attached by a hinge to facilitate accurate repositioning and is realigned or
repositioned over the surface of the cornea, serving as a bandage and expedite healing naturally.
It is used in correcting moderate to high refractive errors such as myopia, hyperopia and
astigmatism, correcting myopia up to 12 D, hyperopia up to 4 D and astigmatism up to 5 D.
LASEK (Laser- assisted subepithelial keratectomy), also a type of laser refractive surgery uses
excimer laser to reshape the cornea. However, it does it by loosening the top layer of the cornea
(epithelium) with ethanol or diluted alcohol solution. The epithelial layer is then brushed away
to access and reshape the corneal stroma with the excimer layer. The epithelial layer is then
reattached and this layer is much thinner than the flaps created in the former. The epithelial
layer of the cornea regenerates in three to five days causing the feeling of discomfort during that
period. In this surgical technique, much tissue is not harvested as compared to the former and it
is the preferred technique for individuals with thin corneas. This is because in LASIK, a residual
corneal base of about 250 micrometers thick must remain after ablation of tissues, hence the
amount of tissue removed equivalent to amount of refractive error correctable is limited by the
original corneal thickness. In this technique, only one laser is used and typically has a longer
recovery time as compared to LASIK. Though LASEK is more invasive, it can be optimal for
significant myopia because it requires more central cornea to be removed.
b. BENEFITS OF LASIK
Quick recovery time: The healing time for LASIK is typically 24-36 hours after the surgery
and most patients are expected to return to their normal activities by the next day or
within few days after the surgery.
Improved vision: About 96%- 98% of patients who undergo LASIK surgery achieve 20/20
vision or experience significant improvement in vision. This reduces or eliminate the
need for glasses and contact lenses. This leads to overall satisfaction and convenience
with daily activities,
Long- lasting results: LASIK surgery provides long-lasting results and most patients
experience permanent improvement in the vision of the patient.
Shorter operative time: the performance of LASIK takes about 10- 15 minutes to
complete which is much quicker and safer as compared to the other procedures.
Minimal discomfort: LASIK is generally associated with minimal discomfort as it is a less
invasive technique compared to LASEK.
DRAWBACKS OF LASIK
Flap- related complications: The superficial flap created during LASIK surgery may cause
flap- related complications such as flap wrinkle, dislodged or disrupted post- surgically.
The flap may cause epithelial ingrowth under the flap and diffuse lamellar keratitis at the
flap interface.
Dry eye symptoms: Patients who undergo LASIK may experience symptoms of dry eyes
such as mild itching and burning sensation which may be uncomfortable. However, these
symptoms typically disappear six months after the surgery, hence patients are advised to
used OTC artificial tears to help with the symptoms.
Night-time glare and halos: About 20% of patients who undergo LASIK surgery
experience glare and halos which are temporary symptom. Though it can affect activities
such as driving, it improves in three to six months post-surgery.
Undercorrection or overcorrection: In some cases of LASIK surgeries, there may be
overcorrection or undercorrection of the patient’s refractive error. This leads to the need
for additional procedures to correct the defect or the continuation of glasses or contact
lenses.
Suitability: LASIK is less suitable for patients with thin corneas as it compromises the
structural integrity of the cornea causing complications such as ectasia. Also, it is less
suitable for patients with dry eyes or those who participate in contacts sports.
BENEFIT OF LASEK
DRAWBACKS OF LASEK.
Longer recovery time: In LASEK, the epithelial layer takes 3-5 days to regenerate.
This slows down the healing time hence it takes a long time for vision to clear. It
typically takes about a week or more to heal and for vision to stabilize.
Discomfort and Pain: Patients who undergo LASEK tend to experience pain and
discomfort such as grittiness, burning sensation and itching of the eye during their
recovery time after surgery. This is usually due to the surface layer of the cornea.
Risk of corneal haze: Patients who undergo LASEK surgery may experience corneal
haze or scarring due to compromised corneal structure which may affect the visual
clarity of the patient and mat require additional treatment.
Risk of epithelial healing issues: LASEK relies on the healing of the epithelial layer of
the cornea and complications such as delayed epithelial healing or epithelial
ingrowth may affect the outcome of the procedure.
Stable refractive error: When a patient's refractive error has stabilized—that is, when their
prescription has stayed mostly steady for at least a year, LASIK is usually advised. This
guarantees that the LASIK correction will be consistent and long-lasting. The patient should
have a stable eyeglasses prescription for about one to two years to be considered for LASIK
surgery.
Adequate corneal thickness: To safely reshape the cornea and improve eyesight, LASIK requires
a specific corneal thickness (480- 500 micrometers). Patients who have enough corneal thickness
are better candidates for laser eye surgery (LASIK) because they are less likely to experience
complications like corneal ectasia, a condition in which the cornea gradually thins and enlarges.
(Ran)
A meta-analysis by Randleman et al. (2008) found that a minimum corneal thickness of 500
micrometers was associated with a lower risk of ectasia after LASIK.
Age: LASIK is generally recommended for individuals over the age of 18, as refractive errors
tend to stabilize by this age. However, the suitability for LASIK can vary depending on
individual circumstances, and older adults may still be considered candidates if they meet other
criteria.
Healthy eye: LASIK candidates should generally have normal vision and no underlying medical
issues including severe dry eye syndrome, glaucoma, or cataracts. Before thinking about LASIK,
any pre-existing eye disorders should be appropriately treated. (renota)
The general health of the patient: Candidates should be in generally good health and free of any
illnesses that could hinder their ability to recuperate or raise their risk of problems after surgery.
Eligibility for LASIK may be impacted by conditions including immunocompromised state,
uncontrolled diabetes, or autoimmune illnesses.
Occupation and lifestyle considerations: When assessing a LASIK candidate, candidates should
take their occupation and way of living into account. Contact sports and high-risk vocations for
eye injuries may call for extra caution or a conversation with the surgeon. Solomon)
This surgical procedure is usually indicated in ptosis secondary to chronic progressive external
ophthalmoplegia (CPEO), third nerve palsy, muscle dystrophy, aponeurotic ptosis in the elderly patient
and congenital ptosis in patients at the risk of amblyopia. In Children this surgical procedure is withheld
until the child is about 3 to 5 years, mainly to allow facial growth and maturation.
In preoperative evaluation, questions o detailed history is considered (past, birth and family history).
Some general and ophthalmological examinations are also carried out including; blood test, thyroid
functioning test, acetylcholine receptor antibody, edrophonium test, jaw wink phenomenon, pupillary
examination, epicanthus and telecanthus, eyelid lag, levator function etc. The procedure can be
performed under general or local anesthesia depending on the type of surgical patient. Studies has
shown there are many surgical approaches to pass the sling material from the eyelid to the brow area
and most of these techniques are based on multiple cutaneous stab incisions at the level of the tarsus
and the eye brow, through which the sling material is passed. Allogenic material, is alternative material.
However, it has a lower long-term effect as compared to fascia lata with the chance of recurrence ptosis.
Synthetic graft materials such as are readily available. Though they are not associated with complications
such as donor site morbidity or cross infections
DOI: 10.1016/j.ophtha.2008.12.037
DOI: 10.4103/0974-9233.63073
Doi; 10.2174/1874364101004010091
doi: 10.2174/1874364101711010176
Anderson RL, Dixon RL. Aponeurotic ptosis surgery. Arch Ophthalmol, 1979;97:1123-8.
Won VA, Beckingsale PS, Oley CA, Sullivan TJ. Management of myogenic ptosis. Ophthalmology. 2002;
109:102331.
Finsterer J. Ptosis causes presentation and management. Aesth Plast. Surg. 2003; 27:193-204
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5. References:
Al-Mohtaseb, Z., Wang, L., Weikert, M. P., & Koch, D. D. (2017). Optical
coherence tomography-based corneal power measurement and
intraocular lens power calculation following laser vision correction (an
American Ophthalmological Society thesis). Transactions of the
American Ophthalmological Society, 115, T8.
Randleman, J. B., Woodward, M., Lynn, M. J., & Stulting, R. D. (2008). Risk
assessment for ectasia after corneal refractive surgery. Ophthalmology,
115(1), 37-50.
Lee, H., Roberts, C. J., Ambrosio Jr, R., Elsheikh, A., & Kang, D. S. (2017).
Predicting ectasia susceptibility in refractive surgery. Journal of Cataract
& Refractive Surgery, 43(3), 394-404.
Solomon, K. D., Fernández de Castro, L. E., Sandoval, H. P., Biber, J. M.,
Groat, B., Neff, K. D., ... & Ying, M. S. (2009). LASIK world literature
review: quality of life and patient satisfaction. Ophthalmology, 116(4),
691-701.
Reinstein, D. Z., Carp, G. I., & Archer, T. J. (2013). Visual and refractive
stability after myopic laser in situ keratomileusis. Journal of Cataract &
Refractive Surgery, 39(1), 7-13.
Santhiago, M. R., Smadja, D., Gomes, B. F., Mello, G. R., Monteiro, M. L.,
& Wilson, S. E. (2015). Association between the percent tissue altered
and post-laser in situ keratomileusis ectasia in eyes with normal
preoperative topography. American Journal of Ophthalmology, 160(5),
851-857.
Kuryan, J., Cheema, A., Chuck, R. S., & Yamamoto, G. (2016). Surgical
outcomes of wavefront-optimized surface ablation and wavefront-
guided surface ablation for correction of moderate and high myopia.
Journal of Refractive Surgery, 32(6), 394-401.
These clinical circumstances are supported by evidence from the literature and
are important considerations in recommending LASIK to patients with
refractive error. However, it's crucial for eye care providers to conduct a
comprehensive evaluation of each patient's individual circumstances and
discuss the potential risks and benefits of LASIK before making a
recommendation.
References:
Al-Mohtaseb, Z., Wang, L., Weikert, M. P., & Koch, D. D. (2017). Optical
coherence tomography-based corneal power measurement and
intraocular lens power calculation following laser vision correction (an
American Ophthalmological Society thesis). Transactions of the
American Ophthalmological Society, 115, T8.
Randleman, J. B., Woodward, M., Lynn, M. J., & Stulting, R. D. (2008). Risk
assessment for ectasia after corneal refractive surgery. Ophthalmology,
115(1), 37-50.
Lee, H., Roberts, C. J., Ambrosio Jr, R., Elsheikh, A., & Kang, D. S. (2017).
Predicting ectasia susceptibility in refractive surgery. Journal of Cataract
& Refractive Surgery, 43(3), 394-404.
Solomon, K. D., Fernández de Castro, L. E., Sandoval, H. P., Biber, J. M.,
Groat, B., Neff, K. D., ... & Ying, M. S. (2009). LASIK world literature
review: quality of life and patient satisfaction. Ophthalmology, 116(4),
691-701.
Reinstein, D. Z., Carp, G. I., & Archer, T. J. (2013). Visual and refractive
stability after myopic laser in situ keratomileusis. Journal of Cataract &
Refractive Surgery, 39(1), 7-13.
Santhiago, M. R., Smadja, D., Gomes, B. F., Mello, G. R., Monteiro, M. L.,
& Wilson, S. E. (2015). Association between the percent tissue altered
and post-laser in situ keratomileusis ectasia in eyes with normal
preoperative topography. American Journal of Ophthalmology, 160(5),
851-857.
Kuryan, J., Cheema, A., Chuck, R. S., & Yamamoto, G. (2016). Surgical
outcomes of wavefront-optimized surface ablation and wavefront-
guided surface ablation for correction of moderate and high myopia.
Journal of Refractive Surgery, 32(6), 394-401.