Referat

KANDIDOSIS
KUTIS
Nadhirah Ananda Idris | 70700120034
Ahmad Fari Arief Lopa | 70700120038

Pembimbing
: Supervisor :

dr. Alifia Ayu Delima Dr. dr. Sitti Musafirah, Sp.KK, FINS-DV

SEBAGAI TUGAS KEPANITERAAN KLINIK

DEPARTEMEN KULIT DAN KELAMIN
FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN
UNIVERSITAS ISLAM NEGERI ALAUDDIN MAKASSAR
2021
 Candidosis cutis is a skin disease caused by a fungal INTRODUCTION
infection of the genus Candida.
As known as superficial candidosis or infeksi kulit-jamur;
infeksi kulit-ragi; kandidosis intertriginosa.

Based on the location of the clinical picture, it is divided into

localized and generalized candidosis
Predilection of Candida albicans in moist areas or the presence
of predisposing factors that support, for example in the skin
folds, people who have immune system
This disease is found throughout the world, can affect all ages,
both men and women
Candida albicans is a common cause of intertrigo candidosis in
elderly and diabetic patients
Kuswadji. Kandidosis. Dalam: Djuanda A., Hamzah M, Aishah S., Ilmu Penyakit Kulit dan Kelamin. Edisi V. Balai Penerbit Fakultas Kedokteran Universitas Indonesia: Jakarta. 2007. Pp: 106-9
Pitchumoni CS, Dharmarajan T. Geriatric Gastroenterology. Springer Science & Business Media; 2012.
Harold R, Mark E, Wilson BB. Cutaneous Candida. MedScape. 2020
 Kandidosis kutis adalah suatu penyakit kulit yang disebabkan PENDAHULUAN
oleh infeksi jamur dari genus Candida.
Nama lain kandidosis kutis adalah superficial candidosis atau
infeksi kulit-jamur; infeksi kulit-ragi; kandidosis intertriginosa.

Berdasarkan letak gaambaran klinisnya terbagi menjadi

kandidosis terlokalisasi dan generalisata
Predileksi Candida albicans pada daerah lembab atau adanya faktor
predisposisi yang mendukung, misalnya pada daerah lipatan
kulit, orang yang memiliki daya tahan tubuh
Penyakit ini terdapat di seluruh dunia, dapat menyerang semua
umur, baik laki-laki maupun perempuan
Candida albicans menjadi penyebab umum kandidosis intertrigo
pada orang tua dan pasien diabetes
Kuswadji. Kandidosis. Dalam: Djuanda A., Hamzah M, Aishah S., Ilmu Penyakit Kulit dan Kelamin. Edisi V. Balai Penerbit Fakultas Kedokteran Universitas Indonesia: Jakarta. 2007. Pp: 106-9
Pitchumoni CS, Dharmarajan T. Geriatric Gastroenterology. Springer Science & Business Media; 2012.
Harold R, Mark E, Wilson BB. Cutaneous Candida. MedScape. 2020
 Candida Albicans

The candida genus is a

heterogeneous group of
approximately 200 species of

Etiology yeast
dimorphic fungi which allow for
70-80% of all candida infections,
making it the most common
cause of superficial and systemic
candidiasis
Living as a saprophyte  isolated
from the skin, mouth, vaginal
mucous membranes, and feces of
normal people
 Candida Albicans

Genus kandida merupakan grup

heterogen kurang lebih 200
spesies ragi

Etiologi jamur dimorfik yang

memungkinkan untuk terjadinya
70-80% dari semua infeksi
candida, sehingga merupakan
penyebab tersering dari
candidiasis superficial dan
sistemik
Hidup sebagai saprofit  diisolasi
dari kulit, mulut, selaput mukosa
vagina, dan feses orang normal
Pathogenesis
Physiological

01 changer
Age, pregnancy,
Systemic Disease
Endochrine disease (diabetes, cushing
menstruation
04 syndrome), down syndrome, uremia,
malignancy, imunodeficiency

Mechaninc factors

02 Trauma (burns, aberasi), local

oclusion, humidity, maseration,
obesity Iatrogenik
05 Catheters, X-ray
radiation, drugs
Nutrition Factors (antibiotics,
03 Avitaminosis, iron
deficiencies, malnutrition
glucocorticoids
Patogenesis
Perubahan Fisiologik

01 Usia, kehamilan,
Penyakit Sistemik
Penyakit endokrin (DM, sindroma
dan haid
04 cushing), Down syndrome, uremia,
keganasan dan imunodefisiensi

Faktor Mekanik
02 Trauma (luka bakar, aberasi),
oklusi lokal, kelembaban,
maserasi, kegemukan Iatrogenik
05 Penggunaan kateter,
radiasi sinar X, obat-
Faktor Nutrisi obatan (antibiotik,
03 Avitaminosis, defisiensi
zat besi, malnutrisi
glukokortikoid
Clasification and clinical symptoms

1. Localized

Candida Candida
Intertrigo
beefy-red patches Perianal
The lesion is
and plaques with macerated like a wet
satellite papules and type dermatophyte
pustules at the infection. This
periphery, with disease causes
eritematous pruritus ani.
Intertriginous areas,
particularly the
axillae,
inframammary folds,
groyn folds, and
2. 3.
Vulvovaginit
In patients with vulvovaginitis,
Balanitis/Balanopostiti
Risk factor  sexual contact
isthick, white, curdlike
a swith a partner suffering
discharge is typical. Pustules vulvovaginitis, diabetes melitis
are seen more frequently in and non-circumcision
balanitis and balanoposthitis Lession  erosi, pustules with
than in vulvitis thin walls, found on the glans
Severe symptoms  burning penis and coronary glandic
sensation, pain after urination, sulcus
dyspareunia, edema labia
minora and superficial ulcer
around the vaginal
Flour albus  yellow
4. Diaper-
Rash
The disorder is triggered by the
presence of yeast colonization in
the gastrointestinal tract.
Infection may occur due to
chronic occlusion of the diaper
area by wet diapers
In the diaper area, the classic
presentation is beefy-red
erythematous plaques with
satellite papules and pustules
3.
Balanitis/Balanopostiti
Risk factor  sexual contact
swith a partner suffering
vulvovaginitis, diabetes melitis
and non-circumcision
Lession  erosi, pustules with
thin walls, found on the glans
penis and coronary glandic
sulcus
 Paronychia

Often suffered by people whose work is related to water, this form is the most common
Candida also has been implicated in chronic paronychia, which presents with erythema of
the proximal nailfold area (boilstering) with loss of the cuticle and skin breakdown
(sometimes with associated onycholysis and nail dystrophy)
swelling without festering, thick, hardened and grooved nails, sometimes brownish, not
brittle, still shiny, there is no remaining tissue under the nails such as tinea unguium,
DIAGNOSIS

0 0 0
1 2 Swab
3
KOH “gold standard”
Culture
pseudohyph taken from an Skin
intact pustule
ae and
if possible
Biopsy
budding
yeast
Treatment
Eliminating or avoiding of
Systemic
predisposig factors
Terbinafine is one of the antifungal derivatives belonging to the
allinamine group The triazole group
This drug is a broad spectrum antimycotic drug. Has the same way of
working with the azole group, Imidazole group.
Ketoconazole was introduced in 1971 as the first effective azole class
anti-fungal. However, due to side effects, safety and efficacy of treatment,

Topical it is not used as a first line against dermatophytes and candida.

-
Gentian violet solution 0,5-1% for mucous membranes, 1-2% skin  twice a day
3days
-
Nystatin : Creams, ointmens, emulsions, in oral candidiasis without
complications given 400 thousand to 600 thousand units 4 times a day
-
Amfoterisin B2
-
Miconazole 2% in the form of cream or powder - Clotrimazole 1% in the form of
powder, solution and cream Thioconazole, bufonazole, isoconazole -
Cyclopyroxolamine 1% solution, cream
Differential Diagnosis

The differential diagnosis of approaching oral candidiasis includes lichen planus, herpes infection, erythema multiforme
and pernicious anemia. It is necessary to consider the possibility of mucositis due to chemotherapy, lupus erythematosus,
histoplasmosis and salicylate toxicity.
Localized candidosis by:
a. Erythrasma: lesions in the folds, the lesions are more red, defined, dry, no satellites, examination with positive wood rays.
b. Intertriginous dermatitis
c. Dermatophytosis (tinea)
d. Psoriasise
e. Seborrheic dermatitis
Prognosis
Generally good, depending on the severity of
the predisposing factors
 Conclusion

Candidosis cutis is a skin disease caused by infection of the fungal genus

Candida on the skin. This disease is found throughout the world, can affect
all ages, both men and women. The cause of fungi is found in healthy people
as saprophytes. Candida infection can occur if there are predisposing factors,
both edogenous and exogenous. Candidosis cutis can be in the form of
intertriginous candidosis, perianal candidosis or generalized skin candidosis.
Meeting Objectives

MARS NEPTUNE VENUS

Despite being red, Neptune is the Venus has a beautiful
Mars is a cold place fourth-largest planet name, but also a
full of iron oxide dust in the Solar System poisonous atmosphere
PATOGENESIS

FAKTOR EKSOGEN FAKTOR ENDOGEN

1. Perubahan Jupiter is a gas giant

fisiologik and the biggest planet
2. Umur in the Solar System
 “This is a quote,
words full of wisdom
that someone important said
and can make the reader
get inspired.”

—Someone Famous
Project Schedule
JAN FEB MAR APR MAY JUN

Phase Jan 1 - Mar 5

1

Task 1 Jan 1 - Feb 15

Phase Apr 1 - Jun 30

2

Task 1 Apr 1 - May 15

Checklist

STRATEGY 1 STRATEGY 2 STRATEGY 3

Describe here your task 1 ✖ ✓ ✓

Describe here your task 2 ✓ ✖ ✖

Describe here your task 3 ✓ ✓ ✖

Describe here your task 4 ✖ ✖ ✓

Describe here your task 5 ✓ ✓ ✓

AwesomeWords
Because key words are great forcatching
your audience’s attention
Project Timeline
MERCURY VENUSVenus
Mercury is the has a beautiful
smallest planet name

01 02 03 04

MARSDespite NEPTUNE
being red, Mars Neptune is the
is cold fourth-largest
KPI Dashboard

201 201 202 *Modify

8 9 0 it!

50% Mar
s
60% Ven
us
40% Eart
h

30 DAYS 45 SHOPS 77 UNITS

Days on market Retailers Inventory

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Status Report

SCHEDULE The project schedule is on track

RESOURCING Resourcing is adequate

BUDGET Project is not within budget

RISKS Most of the project risks are under control

ISSUES There are no major issues

BENEFITS Project benefits exceed the expectations

Review of Concepts

MERCURY VENUS MARS

Mercury is the closest Venus is the second Despite being red,
planet to the Sun planet from the Sun Mars is a cold place

JUPITER SATURN NEPTUNE

Jupiter is the biggest It’s composed of Neptune is the farthest
planet of them all hydrogen and helium planet from the Sun
 A Picture
Is Worth a
Thousand
Words
This Is an Infographic

VENU
S

JUPITER NEPTUNE SATURN

Jupiter is the Neptune is the It’s composed of
biggest planet of farthest planet hydrogen and
them all from the Sun helium
This Is a Map

VENUS
Venus has a
beautiful
name

NEPTUNE
Neptune is
the fourth-
largest
Upcoming Events

JANUARY FEBRUARY MARCH

Monday Tuesday Friday

15 20 28

SATURNSaturn is
MARSDespite being JUPITERJupiter is a
the ringed one. It’s a
red, Mars is actually gas giant and also
gas giant, composed
a cold place full of the fourth-brightest
mostly of hydrogen
iron oxide dust object in the sky
and helium
4,498,300
Big numbers catch your audience’s attention
 80% 30%
Venus has a beautiful name Jupiter is a gas giant

87h
Mercury is the smallest planet
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