HOSSANA COLLEGE OF HEALTH

SCIENCE

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Diagnosis of systemic lupus
Erythmatosus

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Presentation out line

Objective
Diagnosis of systemic lupus Erythmatosus
 Sign and symptom
Implication
 Diagonesis
 Laboratory test
 Treatement
Conclusion
Referance

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Objactive

To know diagnosis of systemic lupus erythmatosus

 To elaborate sign and symptom, implication,
diagonesis, laboratory test and treatement

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Introudactuon

 Systemic Lupus Erythematosus is a complex and

heterogeneous disease that can affect various parts of the
body, including the skin, joints, kidneys, heart, lungs, brain,
and blood cells.
 It predominantly affects women, typically starting in their
childbearing years.

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Signs and Symptoms:

Fatigue
Joint pain and swelling
 Skin rashes, including the
characteristic butterfly-
shaped rash on the face
 Photosensitivity
 Fever
 Hair loss
 Oral ulcers and other .

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 Implications SLE
SLE can have significant implications, including organ
damage
(e.g., kidneys, heart, lungs), increased risk of cardiovascular
diseases, higher susceptibility to infections, complications
during pregnancy, and impact on quality of life.

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Diagnosis

The diagnosis of SLE involves a comprehensive

approach that combines medical history, physical
examination, evaluation of symptoms, and specific
laboratory tests.
Healthcare providers use established criteria, such
as the American College of Rheumatology (ACR)
criteria, to confirm a diagnosis of SLE.

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Laboratory Tests:

Antinuclear Antibody (ANA)

test
Complete Blood Count
(CBC)
Erythrocyte Sedimentation
Rate (ESR) and C-Reactive
Protein (CRP)
Anti-double-stranded DNA
(anti-dsDNA) antibody test
 Complement levels (C3
and C4)

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Treatment

Treatment for SLE aims to manage symptoms, prevent

disease flares, and minimize organ damage. Common
treatment strategies include:-
Nonsteroidal anti-inflammatory drugs (NSAIDs) for pain and
inflammation
Corticosteroids to reduce inflammation
 Immunosuppressants to modulate the immune response
Antimalarial drugs for skin and joint symptoms
 Biologic therapies in severe cases
 Lifestyle modifications, including sun protection and regular
exercise
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Conclusion

Early diagnosis and proactive management of SLE are

crucial for improving patient outcomes and quality of life.
 A multidisciplinary approach involving rheumatologists,
dermatologists, nephrologists, and other specialists is often
necessary for comprehensive care.

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References

Medical textbooks, research articles in rheumatology

journals, and trusted online sources like the Lupus
Foundation of America or the American College of
Rheumatology.
Professional medical guidance from healthcare providers is
essential for the accurate diagnosis and management of SLE.

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THANK U FOR ATTANTION

IN 2016 E.C

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