Biovivid™

Ultra Pure Collagen Peptide

Collagen is the human body’s most
abundant protein, making up around 30%
High
of total protein content. density of Depletion
collagen and Low
The proportion of the collagen types in 100 elastin
of collagen
and elastin density of
% of collagen

skin change with age. Young skin is 80

collagen and
elastin
composed of 80% type I collagen and 60
40
about 15% collagen type III. With age, the 20
ability to replenish collagen naturally 0

decreases by about 1.0%-1.5% per year.

20 30 40 50 60 70 Age (years）

Fig 1. Collagen content of skin decreases with age

(Reilly et al, 2021)

Physiological Functions
Anti-aging

Oral intake of collagen peptides reduces skin wrinkles and increases dermal matrix synthesis

0.50
**
original data (mm3)
Eye winkle volume/

0.45
*
0.40

0.35 Collagen Peptide

Placebo
0.30

0.25

0.20
Baseline 4 weeks 8 weeks

Fig 2. Orally administered collagen peptide led to a statistically Fig 3. Visible reduction of eye wrinkle volume after
significant reduction of eye wrinkle volume 8 weeks of collagen peptide intake.
(Proksch et al, 2014) (Proksch et al, 2014)

A hundred and fourteen women aged 45–65 years were randomized to receive 2.5g of collagen peptide or
placebo, once daily for 8 weeks. There was a statistically significant reduction of eye winkle volume in
comparison to the placebo group after 4 and 8 weeks (20%) of intake.

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 Improve Skin Hydration Support joints and tendons

10.5 25

[12 weeks to baseline]

Skin moisture content

*
10.
20
9.5
Baseline 15
n.s.

ΔVAS
Placebo
9
30 days
Collagen Peptide
8.5 10
+9.1%** +11.8%**
8 5

7.5
0
Control HA HA+Collagen Peptide Pain during Pain during activity Pain at rest
HA: HAPLEX®Plus Sodium Hyaluronate, Collagen: Biovivid TM
Collagen Peptide activity Physician’s evaluation

Fig 4. The changes of skin moisture with oral intake of Fig 5. Differences of VAS scores of the primary
HAPLEX®Plus and BiovividTM outcomes after a 12-week treatment
(Bloomage Biotech clinical test data, 2022) (Denise, 2017)

N=150, aged 30-50 with skin moisture ≤ 12, no The study on young, physically active individuals
gender preference, 30 days demonstrated that the daily intake of 5g of collagen
The HA group and the HA+Collagen Peptide group peptides led to a statistically significant reduction in
had significant changes, skin moisture increasing by activity-related knee joint pain after a 12-week
9.1% and 11.8% respectively. treatment compared with placebo.

Product Category
Biovivid -CF Biovivid -CB Biovivid -CP
Fish collagen peptide Bovine collagen peptide Type Ⅱ collagen

Appearance: Appearance: Appearance:

white powder, granules off white powder, granules Light yellow powder

Particle size: Particle size: Particle size:

40-80-100 mesh 40-80-100 mesh 100 mesh

Molecular weight： Molecular weight： Molecular weight：

2000-3000Da 2000-3000Da <5000Da
1000-2000Da 1000-2000Da
<1000Da <1000Da

Originated from： Originated from： Originated from：

A：Tilapia scales are selected from High quality cowhide or bovine High quality pure chicken
the Amazon River Basin（Kosher） bone as raw materials without breast cartilage as raw material
B：High-quality Tilapia or Sea bass quarantine risk without quarantine risk
scales from Asia marine aquaculture

Dosage: Dosage: Dosage:

2.5-5g/day (+HA+VC) 5-10g/day (+HA+VC+VB) 1-3g/day (+HA+VD+VK2)

Product Advantages
Neutral in taste Excellent solubility No precipitation or flocculation
and odor and clarity Heat-stable in liquid application

Add: No.678 Tianchen St., High-Tech Development Zone, Jinan, China 250101
Tel: +86 531 82685998 Fax: +86 531 82685988
www.bloomagebioactive.com E-mail: customer@bloomagebioactive.com
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