What is

Metabolic Health?
The
dōTERRA
Wellness
Lifestyle
Pyramid
Lifespan
versus
Health-span
Clinical efficacy evaluation-Yeast powder longevity extract
Preface: The aim of the study is to evaluate
the efficacy of yeast powder NMN
Dose : 100mg/day
Dosage form: capsule
Subject conditions: Healthy men and women
aged 50-75
Subjects: 8 people
Method: Take one capsule a day, and conduct
a skin quality test, blood collection, brain age
test, and a somatosensory questionnaire
survey before and 8 weeks after taking it.
Test items:
1. Skin condition
2. Blood test–LDL/HDL, CRP
3. Memory test
4. Healthy-aging related genes
Yeast Powder Longevity Extract Activates Healthy-
aging Gene Expression
Parkin: Mature cells revert to key genes of young cells FOXO: Remove aging cells, protect young cells
Atgs: IImprove cell anti-aging ability and prolong cell lifespan Sirt1: For longevity genes, responsible for regulating important
metabolic functions of the body
*
* 25 Compared to PBMC_Placebo

6 *
* p<0.05
** p<0.01
*** p<0.001

20
5
Placebo

15 Synthetic NMN

4 * Yeast powder

* * 10 * longevity extract

2 * *
3 *
1 5
* *

Parki Atg Atg FOX SIRT 0

0 n 1 8 O 1 NADSYN MRPS5
Yeast Powder Longevity Extract Activates Healthy-
aging Gene Expression
Wrinkles (%) After taking yeast powder NMN for 8 weeks, the
110
skin wrinkles of the subjects were significantly
reduced by 10.3%, and the improvement rate was
105 75.0%.
100
-10.3%
Week 0 Week 8
95

90

85 100.0
80 89.7
75

70

Week 0 Week 8
MetaPWR® Assist
Healthy glucose management after eating
WITHOUT ASSIST
250 Sat. Feb 20
180

70
102
mg/dL
0

WITH ASSIST
250 Sat. Feb 27
180

70
89
mg/dL
0
MetaPWR ® No glucose
lowering (A)

Assist
• It’s not just about average
glucose levels
• Smooth post-meal spikes
• Glucose spikes = oxidization
= AGING Hanssen NMJ, Kraakman MJ, Flynn MC, Nagareddy PR, Schalkwijk CG, Murphy AJ. Postprandial Glucose
Spikes, an Important Contributor to [Metabolic Health]. Front Cardiovasc Med. 2020;7:570553. Published
2020 Sep 18. doi:10.3389/fcvm.2020.570553
Oxidization
= Aging
Oxidization
“Rusting” from the inside
MetaPWR ®

Advantage
NAD+ to combat
oxidization
 Up to 40 participants

2 weeks

MetaPWR ®
1 MetaPWR® Advantage

Advantage Trial sachet per day

Safety and efficacy

markers
 42.6 yrs
Average Age

MetaPWR ®
1:1
Advantage Male:Female Ratio

Quantitative +47.1%
Data
NAD+

+59.2%
NADH
MetaPWR ® +3%
Skin Health

Advantage +25%
Qualitative Data Energy Levels

+23%
Sleep
Usage Graph

Sunday Monday Tuesday Wednesday Thursday Friday Saturday

Advantage x x x x
Blend x x
Assist x x x

Fat Glucose
NAD
Accumulation Spikes
 Advantage
• Morning: 72%
• Afternoon: 5%
• When Needed: 23%

Usage Survey – Assist

Time of day • Before Meal: 67%

• After Meal: 23%
• When Remembered: 10%
Formulated with MetaPWR™ Resveratrol
Metabolic Blend
Synergistic
Known for: May increase NAD+ in the
body, according to preclinical studies. *†
Known for: Curbs
cravings and may

Ingredients inhibit fat cell growth*†

Sea Buckthorn Fruit Extract
Known for: Promotes antioxidant activity. *

Marine Collagen Tripeptides Rose Apple Fruit Extract

Known for: Strengthens skin, joints, and connective Known for: Promotes
tissues, supporting mobility and elasticity.* antioxidant activity.*

Red-Orange Fruit Extract Phytoceramides

Known for: Promotes antioxidant activity. * Known for: Promotes healthy
cellular aging and skin firmness. *
Nicotinamide
Mononucleotide (NMN)
Known for: May increase NAD+ in the Liposomal Vitamin C
body, according to preclinical studies. *†
Known for: Provides antioxidant with
immunity benefits and may stimulate
NADH the biosynthesis of collagen. *
Known for: May increase NAD+ in the
body, according to preclinical studies. *†
Biotin
Hyaluronic Acid Known for: Promotes healthy utilization of fats, carbs,
Known for: Promotes healthier, more supple skin. * and amino acids and supports hair, skin and nails. *

†More confirming clinical research is needed.

*These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
 Sea Buckthorn
Fruit Extract
Stem Cell Known for: Promotes antioxidant activity.

Mobilization
Tibetan Plateau
Polyphenols,
Proanthocyanidins,
Bioflavonoids
Rose Apple
Fruit Extract
Known for: Promotes antioxidant activity.

Australia
Anthocyanins,
Chlorogenic acid, Gallic
acid
 FIVE PILLARS OF
M E TA B O L I C H E A LT H

Healthy eating Stress management

Daily movement Smart supplementation

Healthy
connections
 Proactive Health
Care

Informed Self-care

Reduce Smart Supplementation

Synthetic Exposure

Healthy Connections &

Rest & Manage Stress Stress Management

Movement & Metabolism Daily Movement

Nutrition & Digestion Healthy Eating

Personal Wellness Realised
Blood Pressure

Daily Movement Rest & Stress Management

Lipid Metabolic Health Blood Sugar

Healthy Eating & Healthy Connections

Supplementation

Weight
Be a Product of
the System
 Journey Not Destination

It's Personalised Forest Not Trees

Wellness
Health & Wellness Not Better
Realised Living Through Quick Fixes

Consistent Efforts to Support

Ourselves and the People We
Love
You can take control
of your Metabolic Health
Thank you!