Newborn Sepsis1
Newborn Sepsis1
Submitted by Group D
BSN – 2D
Clinical Instructor
MAY 25 2024
Table of Contents
A. Case Description
● Risk Factors
● Complication
● Management/Treatment
B. Anatomy and
Physiology C. Nursing
History
● Demographic data
● Familial Tendency
D. Nursing Assessment
G. Pathophysiology
H. Drug Study
A. CASE DESCRIPTION
Neonatal sepsis
Sepsis in newborns, or neonatal sepsis, is a serious medical
condition that occurs when a baby younger than 28 days old has
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
Types of sepsis
Early-onset neonatal sepsis: Most providers use the term
“early-onset neonatal sepsis” to describe sepsis that
develops within the first 72 hours of life.
Causes of SEPSIS
Bacterial infections are the most common cause of sepsis in
newborns. Bacteria such as E. coli, Listeria and Group B
streptococcus (GBS) are common bacteria that can cause
infections that lead to sepsis.
Viruses, fungi and parasites can also lead to the condition. For
instance, the herpes simplex virus (HSV) can cause severe
infections in newborns.
MANAGEMENT/TREATMENT OF GASTROENTERITIS
Immune System
Neonates have an immature immune
system with limited ability to mount
an effective response to infections.
The barriers such as skin and mucous
membranes are not fully developed,
and the production of antibodies is not
fully mature.
Central Nervous
System (CNS):
The blood-brain barrier is more
permeable in neonates, making
the CNS more susceptible to
infections like meningitis.
Cardiovascular System
Newborn have a higher heart rate and lower blood pressure compared to older
children and adults. They are also more prone to rapid deterioration in cardiac
function during sepsis due to limited cardiovascular reserve.
Physiology
Immune Response: Neonates rely heavily on innate immunity, including
neutrophils and macrophages. However, these cells have diminished chemotaxis
and phagocytic activity. Adaptive immunity, including T and B cells, is not fully
functional, and immunoglobulin levels (except IgG transferred from the mother) are
low.
C. NURSING HISTORY
1. Demographic Data
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
N/A
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
BEFORE DURING
His health is being controlled by
The mother of the baby stated
adhering to the prescribed
that he is healthy and received
drugs.
Hepa B Vaccine
NUTRITIONAL METABOLIC
BEFORE DURING
ELIMINATION PATTERN
BEFORE DURING
BEFORE DURING
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
No changes noted.
The baby rise from his sleeps
every time he is hungry as
verbalized by the his mother.
Sleep-Rest Pattern
BEFORE DURING
The baby usually sleeps after he fed by The mother stated that the sleeping
his mother. pattern of the baby is same schedule as
before.
The mother stated that the baby can hear and The mother stated that the baby cries more
noise.
BEFORE DURING
N/A N/A
BEFORE DURING
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
SEXUALITY – REPRODUCTIVE
BEFORE DURING
N/A
N/A
VALUES- BELIEFS
BEFORE DURING
D. NURSING ASSESSMENT
Rounded, no tenderness
upon palpation
round, reactive
NOSE Inspection
to light
and NORMAL
accomodation.
SUNKEN
MOUTH Inspection EYE
ABNORMAL: DUE
BALL
TO
DEHYDRATION
Nose in the
midline
Has no
discharge
DRY MUCUS
MEMBRANE
DRY
LIP
R
CHEST
Absence of NORMAL
lesions and
masses.
GENITOU-
RINARY Inspection Absence of NORMAL
SYSTEM lesions and
masses
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
NORMAL
UPPER SKIN Inspection Free of Lesions
EXTREMITI AND Palpation
ES NAILS SKIN IS DRY ABNORMAL: DUE T
FLUID LOSS
CAPILLARY
REFILL TIMES
IS MORE THAN
2 SEC.
HEMATOLOGY
29-37 gldl
MCHC 34.8
DIFFERENTIAL COUNT
Stabs
Blast
ESR M.0-10mmHg
5/21/24
GRAM STAIN
Rare
Pus cells /LPF
Epithelial Rare
cells/ OFT
Predominating MO microorganism
organism / see
OFT
Other
organism / OIT
CSF ANALYSIS
Clarity Clear
Viscosity Non-viscous
Chemistry
Glucose 41 40-70mg/dl
Hematology
5/20/24
SARS-COVS-ANTIGEN
QUALITATIVE TEST
FBS
RBS
Neonatal 237.8 17-180 umol/L
bilirubin
Triglycerides 0..0 Neonate; 0-10
umol/L
LDL 237.8 Neonate 10-180
umol/L
Continuing breastfeeding
in infants who have had
newborn sepsis is
important because breast
milk provides essential
nutrients and antibodies
that can help boost the
baby's immune system
and fight off infections.
Additionally,
breastfeeding promotes
bonding between the
mother and baby, which
is crucial for their
emotional and
o Monitor V/S q4
psychological well-being.
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
Vitamin B1 (thiamine)
and B2 (riboflavin)
testing may be included
to assess the baby's
nutritional status, as
sepsis can lead to
increased metabolic
demands and potential
deficiencies in essential
vitamins. Maintaining
adequate levels of these
vitamins is important for
overall health and
o Meropenem recovery.
135mg IV q 8
Administering
meropenem 135mg
intravenously every 8
hours helps ensure
adequate therapeutic
levels of the antibiotic in
the baby's bloodstream
to effectively combat
the infection. The dosing
regimen is typically
determined based on
the baby's weight, age,
and severity of the
infection, with
adjustments made as
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
o Amikacin 45 mg
IV OD Administering Amikacin,
an antibiotic, to a
newborn with sepsis is a
treatment to combat the
infection. The dosage of
45 mg IV OD (once
daily) would be based on
the baby's weight, age,
and severity of the
infection. It's important
to follow the prescribed
dosage and regimen to
effectively treat the
sepsis and prevent
o For continuous complications.
phototherapy
with proper Continuous
shield phototherapy is often
used in newborns with
sepsis who also develop
jaundice. Newborn
sepsis can stress the
liver, leading to an
increase in bilirubin
levels, which causes
jaundice. Continuous
phototherapy helps to
break down excess
bilirubin in the
bloodstream, reducing
the risk of complications
such as kernicterus (a
type of brain damage).
It's important to manage
jaundice promptly in
newborns with sepsis to
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
prevent further
complications and
support the baby's
recovery
o NPO @ 8am
If the baby needs a
diagnostic test or a
procedure that requires
anesthesia or sedation,
it's essential to keep the
stomach empty to
reduce the risk of
aspiration (inhaling
stomach contents)
during the procedure.
Additionally, NPO status
might be necessary if
the baby is receiving
certain medications that
require an empty
stomach for optimal
absorption or to
o HGT @ 9am minimize potential side
effects.
Diazepam, a
benzodiazepine, is
mainly used to treat
seizures, anxiety, and
muscle spasms, but it's
not the first-line
treatment for sepsis. If
the baby is experiencing
seizures, appropriate
anticonvulsants would
be considered, but the
choice and dosage
should be determined by
a pediatrician or
neonatologist.
o Flat on bed
aspiration (inhaling
stomach contents)
during the procedure.
Additionally, NPO status
might be necessary if
the baby is receiving
certain medications that
require an empty
stomach for optimal
absorption or to
o Send CIF minimize potential side
Cell count and DID effects.
count >Protein
> Cal cy op Sending tests like
complete blood count
(CBC), differential count
(DID), protein levels,
and cerebrospinal fluid
(CSF) analysis to a baby
with newborn sepsis
helps healthcare
providers monitor the
baby's response to
treatment, assess the
severity of the infection,
and detect any
complications. These
tests provide valuable
information about the
baby's immune
response, organ
function, and overall
o Intermittent health, guiding
Phototherapy treatment decisions and
and proper shield adjustments as needed.
Intermittent
phototherapy and
proper shielding are
often used in babies
with newborn sepsis to
manage jaundice, a
common condition in
newborns. Jaundice can
occur as a result of
various factors,
including sepsis.
Phototherapy helps
break down excess
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
An EEG
(electroencephalogram)
may be performed on a
baby with newborn
sepsis to assess brain
function and detect any
abnormalities, such as
seizures or abnormal
electrical activity. Sepsis
can affect various organ
systems, including the
central nervous system,
and can lead to
neurological
complications. An EEG
helps healthcare
providers evaluate the
baby's neurological
status, guide treatment
o Diphenhydramin decisions, and monitor
e 3.5 mg IV push for any signs of
now neurological impairment
or damage associated
with sepsis
Administering
diphenhydramine
intravenously (IV) to a
baby with newborn
sepsis may be indicated
for various reasons,
such as treating allergic
reactions, managing
itching or hives, or as a
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
pre-medication before
certain procedures or
medications.
Diphenhydramine is an
antihistamine that can
help relieve symptoms
of allergies and allergic
reactions. However, the
specific dosage and
administration of
diphenhydramine should
be determined by a
o Continue Med healthcare professional
based on the baby's
weight, age, medical
history, and the severity
of their condition
Continuing medication
for a baby with newborn
sepsis is essential to
ensure that the infection
5/23/24 is effectively treated and
to prevent any
recurrence or
complications.
Antibiotics are typically
o Continue Med continued for a specific
duration to ensure
complete eradication of
the infection.
Continuing medication
for a baby with newborn
sepsis is essential to
ensure that the infection
is effectively treated and
to prevent any
recurrence or
complications.
Antibiotics are typically
o Repeat TB,B1,B2 continued for a specific
duration to ensure
complete eradication of
the infection.
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
Repeating diagnostic
tests such as Tb
(tuberculosis testing),
B1, and B2 for a baby
who had newborn sepsis
may be necessary to
monitor the baby's
response to treatment,
assess for any new
developments or
complications, and
ensure that the infection
has been adequately
managed. These tests
can provide valuable
information about the
baby's health status and
help healthcare
providers make
informed decisions
about ongoing
treatment and care.
Regular monitoring is
essential to track the
baby's progress and
adjust the treatment
plan as needed.
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
G. PATHOPHYSIOLOGY
UNIVERSITY OF LA SALETTE
Dubinan East, Santiago City 3311, Isabela, Philippines
COLLEGE OF NURSING, PUBLIC HEALTH, AND MIDWIFERY
I. DISCHARGE PLANNING
MEDICATION
TREATMENT
Treatment after discharge of a neonate with sepsis may
require to aimed at the overwhelming systemic effects of the
disease.
HEALTH TEACHING