FEMALE GENITAL SYSTEM

UTERUS

PLACENTA

OVARY

UTERUS

1)Carcinoma

2)Adenomyosis

3) Leiomyoma

1. 2. 3. 4.

SIZE UTERINE CAVITY TUMOR MYOMETRIUM

1. 2. 3. 4.

UTERINE WALL MYOMETRUM ADENOMYOSIS ENDOMETRIUM

1. UTERINE CAVITY 2. CUT SECTION 3. TUMOR

CARCINOMA OF BODY OF UTERUS

Size: moderately increase Uterine cavity: Mass filling at upper half Tumor: Fungating + irregular + friable + ulcerated Myometrium: Thickened by malignant invasion

ENDOMETRIAL HYPERPLASIA WITH ADENOMYOSIS

ADENOMYOSIS

Similarities Uterine wall: Moderate symmetric thickening Adenomyosis: numerous + small + grayish + translucent cyst Myometrium: Hypertrophy

Differences in endometrium THICKENED + GRANULAR + POLYPOIDAL PROJECTION

NORMAL

Leiomyoma
Multiple uterine Leiomyomata Uterine Leiomyoma of Fatty change

Uterine leiomyoma of myxomatous degeneration

Similarities 1) Uterine Cavity: Compressed + distorted 2) Cut Section: Whorly appearance of smooth ms fibre + separated by white fibrous bands

MULTIPLE UTERINE LEIOMYOMATA

Differences Outer surface: irregular + nodular Cut surface: multiple nodular area ( variable size) Location: Interstitial/ subserosa/ submucous Endometrium: thin + atrophy

FATTY CHANGE OF UTERINE LEIOMYOMA

MYXOMATOUS DEGENERATION OF UTERINE LEIOMYOMA

Differences in TUMOR TISSUE yellowish area denoting fatty change

multiple cystic space (variable size and shape) jelly like semitranslucent mucoid material myxomatous degeneration

DISEASE OF PLACENTA

HYDATIFORM MOLE/VESICULAR HYDATIFORM MOLE/VESICULAR MOLE (COMPLETE) MOLE (PARTIAL) Similarities Multiple small vesicles Vesicles: grape like structure ( variable size and shape)thin wall Contain: semitranslucent fluid Connected by delicate fibrous tissue

DIFFERENCES NO FETAL PART

FETAL PART ARE CLEARLY SEEN

DISEASE OF OVARY

Papillary serous cystadenoma

Cyst: Unilocular Cavity of cyst: complex papillary structure + grayish brown + project into cavity Serosal: smooth

DISEASE OF ENDOCRINE

Thyroid adenoma with calcification

Similarities NODULE: Size: 4 cm in diameter Consistency : firm

Thyroid ( solitary thyroid nodule)

Colour : brownish Capsule : fibrous tissue capsule

Differences in cut surface

chalky white area of dystrophic calcifications Brownish in color with gelatinous brownish colloid

MULTINODULAR GOITER
GLAND -asymetrically enlarged -consistency :firm external surface : nodular Nodules : -cut surface: contain brownish colloid -size: variables -seperated by white bands of fibrous tisssue -some shows degenerative changes in form of 1. Cyst formation 2. Haemorrage 3. Necrosis

DISEASE OF BONE

OSTEOCLASTOMA (GIANT CELL TUMOR OF FIBULA)

OSTEOSARCOMA (OSTEOGENIC SARCOMA OF FIBULA)

Differences
OSTEOCLASTOMA 1)Site: end of fibula : oval tumour mass 2)Tumour -expansion + thinning of fibula (egg shell crakling sensation) -bone: destroyed - cortex: reduced to thin shell 3)Cut surface -haemorrhage -necrosis - cyst formation 4)No new bone formed OSTEOSARCOMA 1)Site: medulla : fusiform swelling 2)Tumour - grayish brown -fleshy with small foci -cortex: invaded by tumour = destruction + elevation of periosteum

3)New bone formed