Professional Documents
Culture Documents
Modifiable
Non-Modifiable
Age
Congenital heart disease
Gender
Preexisting heart conditions
IV drug use
Environment
Prosthetic valve surgery
(PVE)
Immunosuppressed
Platelet-firbrin thrombus
Bacteremia
Immune
system
activation
Bacterial
vegetation on
thrombus
Excretion of glycocalyx
Cytokine production
WBC
Fever/Chills
Bacterial
thrombus
development on
edges of heart
valves
Biofilm
Valvular dysfunction
/Regurgitation
30-40% of pts
develop CHF
Decreased
peripheral
perfusion
Cardiac valve
insufficiency
Heart murmurs
Increased O2 demand
Hypertension
Embolization of vegetation
Septic emboli lodges
into different parts of
the body
Non-immunologic
response
Antigen-Antibody
complex
Pulmonar
y Artery
Brain
Under
fingernail
s
Fingers,
toes,
noes,
earlobes
Pulmonary
Embolism
Stroke
Splinter
hemorrhages
Janewa
y
lesions
Hands, feet
Eyes
Kidneys
Oslers Nodes
Roth
spots
Glomurulonephritis