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GALLSTONE &

GALLBLADDER DISEASE
Dr Uhuebor DI
MB,BS (Lagos)

Gallstone is crystalline concretion formed


within the gallbladder.

ANATOMY
Gallbladder is a hollow organ that lies
beneath the liver.
It concentrates bile produced by the liver.

-which helps with fat digestion


the gallbladder tapers into the cystic duct +
common hepatic = common bile duct

May lead to;


- cholelithiasis/cholecystitis
- choledocholithiasis
-ascending cholangitis
-gallstone pancreatitis

Biliary colic- obstruction in the cystic duct


Cholecystitis- biliary colic + surrounding
inflammation.
-acalclous cholecystitis: in debilitated px
Choledocholithiasis- blockage in the common
bile duct.ALP,GGT
Cholangitis- infection of the entire biliary
tree. life threatening. Charcots triad

CAUSES

Female
Forties
Fat
Fair
Drugs
Diet
Blood disorders

SIGNS & SYMPTOMS

Abdominal pains- usually RUQ


Nausea/ Vomitting
Fever
Jaundice
Belching
Bloating

INVESTIGATIONS

Abdominal X-rays
Abdominal USS
Abdominal CT
Cholangiogram

TREATMENT
Medical use of ursodeoxycholic acid
ECSL
Surgical:
-open
-laparoscopic

COMPLICATIONS

Empyema
Perforation
Gangrene
Fatty acid and fat soluble vitamin
malabsorption

POSTCHOLECYSTECTOMY
SYNDROME
5 - 40% of px
abdominal symptoms after cholecystectomy.
-upset stomache, nausea & vomitting
-gas, bloating & diarrhea
-RUQ pain

Due to;
-sphincter of Oddi dysfunction
-post surgical adhesions
-remaining stones
-choledochocyst
-biliary injury

Thank you

References
Kim IS, Myung SJ, Lee SS, Lee SK, Kim MH (2003).
"Classification and nomenclature of gallstones revisited" . Yonsei
Medical Journal 44 (4): 56170. ISSN0513-5796. PMID12950109
.
http://www.eymj.org/Synapse/Data/PDFData/0069YMJ/ymj-44-561.
pdf
.
National Institute of Diabetes and Digestive and Kidney Diseases
(2007). "Gallstones". Bethesda, Maryland:
National Digestive Diseases Information Clearinghouse ,
National Institutes of Health ,
United States Department of Health and Human Services .
http://digestive.niddk.nih.gov/ddiseases/pubs/gallstones/Gallston
es.pdf.

Roizen MF and Oz MC, Gut Feelings: Your


Digestive System, pp. 175206 in Roizen and
Oz (2005)
National Health Service (2010).
"Gallstones Treatment". NHS Choices:
Health A-Z - Conditions and treatments.
London: National Health Service.
http://www.nhs.uk/conditions/gallstones/pag
es/treatment.aspx
.

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