CHRON'S DISEASE

DEFINITION
AN INFLAMMATORY DISEASE
-CAN AFFECT ANY PART OF THE GI
TRACT (USUALLY THE TERMINAL
ILEUM), EXTENDING THROUGH ALL
LAYERS OF THE INTESTINAL WALL.

CAUSES
UNKNOWN
ALLERGIES, IMMUNE DISORDERS,
LYMPHATIC OBSTRUCTION,
INFECTION, GENETIC FACTORS.

SIGNS AND SYMPTOMS

FEVER AND FATIGUE
ABDOMINAL PAIN AND CRAMPING
BLOOD IN YOUR STOOL
MOUTH SORES
REDUCED APPETITE AND WEIGHT LOSS

DIAGNOSIS
INCREASED WBC AND ESR
HYPOKALEMIA, HYPOCALCEMIA, HYPOMAGNESEMIA
DECREASE HEMOGLOBIN
BARIUM ENEMA
SIGMOIDOSCOPY/COLONOSCOPY
BIOPSY

TREATMENT
ANTIBIOTICS CAN REDUCE THE AMOUNT OF DRAINAGE AND
SOMETIMES HEAL FISTULAS AND ABSCESSES IN PEOPLE WITH
CROHN'S DISEASE.(E.G. METRONIDAZOLE (FLAGYL),
CIPROFLOXACIN (CIPRO). )
CORTICOSTEROIDS. CORTICOSTEROIDS SUCH AS PREDNISONE
CAN HELP REDUCE INFLAMMATION
ORAL 5-AMINOSALICYLATES. THESE DRUGS MAY BE HELPFUL IF
CROHN'S DISEASE AFFECTS YOUR COLON, BUT THEY AREN'T
HELPFUL TREATING DISEASE IN THE SMALL INTESTINE.

TREATMENT
-IMMUNOSUPPRESANTS (-MERCAPTOPURINE
(PURINETHOL) AND AZATHIOPRINE (IMURAN)
-ANTICHOLINERGIC DRUGS
-INCREASE CALORIE AND PROTEIN INTAKE;
BLAND DIET WITH VITAMIN C AND IRON
COMPOUNDS TO COMPENSATE FOR ANEMIA

THANK YOU :)