Bessy Game

Hi bes!
Among the aminoglycosides,
streptomycin and gentamicin are:

A. Most nephrotoxic
B. Most ototoxic
C. Most vestibulotoxic
D. Most hepatotoxic
streptomycin and gentamicin are:

C. Most vestibulotoxic
It is a prototype drug which has poor CSF
penetration and must be administered with enteric
coating.

A. Azithromycin
B. Erythromycin
C. Clarithromycin
D. Spectinomycin
B. Erythromycin
Drug of choice for rickettsial
infection:

A. Tetracycline
B. Spectinomycin
C. Amikacin
D. Tobramycin
A. Tetracycline
Kapit bes!
I trust you besh!
Chloramphenicol is bacteriCIDAL to
what strain of bacteria?

A. S. epidermidis
B. S. aureus
C. M. pneumoniae
D. B. fragilis
D. B. fragilis
Example of 30s inhibitor:

A. Aminoglycosides
B. Tetracycline
C. Both
D. Neither
C. Both
A. Aminoglycosides
B. Tetracycline
Newer aminoglycosides except:

A. Gentamycin
B. Tobramycin
C. Amikacin
D. Streptomycin
D. Streptomycin
All are 50s inhibitors, except:

A. Chloramphenicol
B. Macrolides
C. Tetracyclines
D. Streptogramins
C. Tetracyclines
Short-acting aminoglycosides except:

A. Tetracycline
B. Oxytetracycline
C. Doxycycline
D. Chlortetracycline
C. Doxycycline
The following is/are characteristics of
tetracycline:

(A) broad spectrum

bacteriostatic
(B) bind to 50s subunit
(C) both
(D) neither
characteristic/s of tetracycline:

A. broad spectrum
bacteriostatic
Sorry bes!
This drug can eradicate
meningococcal carrier state.

A. Minocycline
B. Doxycycline
C. Demeclocycline
D. Tetracycline
This drug can eradicate
meningococcal carrier state.

D. Tetracycline
 4th generation Cephalosporin

A. Cephalexin and Cefotetam

B. Cefuroxime and Cafazolin

C. Ceftriaxone and Cefepime

D. Meropenem and Vancomycin

4th generation Cephalosporin

C. Ceftriaxone and Cefepime

Tetracycline enter microorganisms
through:

(A) energy dependent active

transport
(B) passive diffusion
(C) both
(D) neither
Ans. C. both
Tetracycline enter microorganisms through:
energy dependent active transport
passive diffusion
The following drugs block peptide bond
formation by binding with 50S subunit:

(A) Tetracycline
(B) Macrolide
(C) both
(D) neither
B. Macrolide
The ff is/are 30S inhibitor
a. aminoglycoside
b. clindamycin
-D

c. tetracyclin
d. a & c
e. none of the above
D. a&c
a. Aminoglycoside
c. tetracyclin
used for bowel preparation for
elective surgery

a. streptomycin
b. clindamycin
c. kanamycin
d. neomycin
e. c&d
E. c&d
clindamycin
neomycin
True about spectinomycin

a. related to amoniglycoside
b. 30s subunit
c. nephrotoxic
d. a & c
e. all of the above
E. all of the above
Tigecycline is a substrate of the chromosomally encoded multidrug
efflux pumps of -_________ and _________ , accounting for their
intrinsic resistance to all tetracyclines including tigecycline.

a. Staphyloccoccus aures and Listeria

Monocytogenes
b. Neisseria meningitides and Enterococcus
sp.
c. Pseudomonas aeruginosa and Proteus sp
d. Streptococcus pneumoniae and
Pneumococcus
ANSWER: C
Pseudomonas aeruginosa and Proteus sp
Quinupristin-dalfopristin, a Streptogramin, is
active against E faecium but not with:

a. Haemophilus influenzae
b. Enterococcus faecalis
c. Moraxella catarrhalis
d. Streptococcus pyogenes
ANSWER: B
Enterococcus faecalis
This prevents bacterial protein synthesis by
binding to the 50S ribosomal subunit.

a. Gatifloxin
b. Sisomycin
c. Methacyclin
d. Tedizolid
ANSWER: D.
Tedizolid
50S inhibitor and the activity is
enhanced at Alkaline pH .

A.Chloramphenicol
B. Streptogramins
C. Macrolides
D. A&B
C. Macrolides
More effective than Tetracyclines against
Typhoid fever & other Salmonella infections.

A. Chloramphenicol
B. Streptomycin
C. Minocycline
D. Doxycycline
A. Chloramphenicol
Macrolide that does not inactivate cytochrome
p450 enzymes and free of the drug interactions.

A. Clarithromycin
B. Azithromycin
C. A&B
D.neither
B. Azithromycin
Synthesis of 1st polypeptide bond to
addition of the last amino acid:

A. Elongation
B. Initiation
C. Termination
D. Dissociation
A. Elongation
Drug that shortens the half-life of doxycycline by
induction of hepatic enzymes that metabolize the
drug:

A. Carbamazepine
B. Chloramphenicol
C. Spectinomycin
D. Demeclocycline
A. Carbamazepine
Part of new generation macrolide
except:

A. Roxithromycin
B. Erythromycin
C. Azithromycin
D. Dirithromycin
B. Erythromycin
The mechanism of action of this drug is attachment to the 50s
ribosomal unit, inhibition of protein synthesis by interfering with
the formation of initiation complexes and translocation reaction.

A. Clindamycin
B. Azithromycin
C. Erythromycon
D. Streptogramins
A. Clindamycin
Congrats!!!
Youre the best!