L. J. SALOMON, Z. ALFIREVIC, V. BERGHELLA, C. BILARDO, E.

HERNANDEZ-
ANDRADE, S. L. JOHNSEN, K. KALACHE, K.-Y. LEUNG, G. MALINGER, H. MUNOZ, F.
PREFUMO, A. TOI and W. LEE on behalf of the ISUOG Clinical Standards Committee
 Why ?
The International Society of Ultrasound in Obstetrics and Gynecology
(ISUOG) is a scientific organization that encourages sound clinical practice,
teaching and research for diagnostic imaging in womens healthcare.
Practice Guidelines and Consensus are intended to reflect what is
considered by ISUOG to be the best practices at the time at which they
were issued.
Although ISUOG has made every effort to ensure that guidelines are
accurate when issued, neither the Society nor any of its employees or
members accepts any liability for the consequences of any inaccurate or
misleading data, opinions or statements issued by the CSC.
Guidelines are not intended to establish a legal standard of care because
interpretation of the evidence that underpins the guidelines may be
influenced by individual circumstances and available resources.
Approved guidelines can be distributed freely with the permission of ISUOG
(info@isuog.org).
 What is the purpose of a mid-trimester
fetal ultrasound scan?
Provide accurate diagnostic information for the delivery of optimized
antenatal care with the best possible outcomes for mother and fetus.
The procedure is used to determine gestational age and to perform fetal
measurements for the timely detection of are to detect congenital
malformations and multiple pregnancies.
Prenatal screening examination includes an evaluation of the following:
cardiac activity; fetal number (and chorionicity if multiple pregnancy); fetal
age/size; basic fetal anatomy; placental appearance and location.
Although many malformations can be identified, it is acknowledged that
some may be missed, even with sonographic equipment in the best of
hands, or that they may develop later in pregnancy.
Before starting the examination, a healthcare practitioner should counsel
the woman/couple regarding the potential benefits and limitations of a
routine mid-trimester fetal ultrasound scan.
 Who should perform the scan?
In order to achieve optimal results from routine screening examinations, it is
suggested that scans should be performed by individuals who fulfil the
following criteria:
trained in the use of diagnostic ultrasonography and related safety issues;
regularly perform fetal ultrasound scans;
participate in continuing medical education activities;
have established appropriate referral patterns for suspicious or abnormal
findings;
routinely undertake quality assurance and control measures.
If the examination cannot be performed completely in accordance with
adopted guidelines, the scan should be repeated, at least in part, at a later
time, or the patient can be referred to another practitioner. This should be
done as soon as possible, to minimize unnecessary patient anxiety and
unnecessary delay in the potential diagnosis of congenital anomalies or
growth disturbances.
 What equipment?
For routine screening, equipment should have at least the following:
real time, gray-scale ultrasound capabilities;
transabdominal transducers (35-MHz range);
adjustable acoustic power output controls with output display
standards;
freeze frame capabilities;
electronic calipers;
capacity to print/store images;
regular maintenance and servicing, important for optimal equipment
performance.
 What document?
An examination report should be produced as an electronic and/or a
paper document, to be sent to the referring care provider in
reasonable time. A sample reporting form is available at the end of
this guidelines.
Images of standard views (stored either electronically or as printed
copies) should also be produced and stored. Motion videoclips are
recommended for the fetal heart.
Local laws should be followed. Many jurisdictions require image
storage for a defined period of time.
 Is prenatal ultrasonography safe?

Prenatal ultrasonography appears to be safe for clinical

practice.
To date, there has been no independently confirmed study to
suggest otherwise.
Fetal exposure times should be minimized, using the lowest
possible power output needed to obtain diagnostic
information,
following the ALARA principle (As Low As Reasonably
Achievable).
More details are available from the ISUOG Safety Statement.
 Well being?
Amniotic fluid assessment:
Amniotic fluid volume can be estimated subjectively or using
sonographic measurements.
Subjective estimation is not inferior to the quantitative measurement
techniques (e.g. deepest pocket, amniotic fluid index) when performed
by experienced examiners.
Fetal movement:
Normal fetuses typically have a relaxed position and show regular
movements.
There are no specific movement and temporary absence or
reduction of fetal movements during the scan should not be considered
as a risk factor. Abnormal positioning or unusually restricted or
persistently absent fetal movements may suggest abnormal fetal
conditions such as arthrogryposis. The biophysical profile is not
considered part of a routine mid-trimester scan.
 Fetal biometry?
The following sonographic parameters can be used to estimate
gestational age and for fetal size assessment:
biparietal diameter (BPD);
head circumference (HC);
abdominal circumference (AC) or diameter;
femur diaphysis length (FDL).
Measurements should be performed in a standardized manner on the
basis of strict quality criteria. An audit of results can help to ensure
accuracy of techniques with regard to specific reference tables.
The chosen reference standards should be indicated in the report
An image(s) should be taken to document the measurement(s).
The application of Doppler techniques is not currently recommended
as part of the routine second-trimester ultrasound examination. There
is insufficient evidence to support universal use of uterine or umbilical
artery Doppler evaluation for the screening of low-risk pregnancies.
 Fetal anatomy?
Recommended minimum requirements for a basic fetal anatomical
survey during the mid-trimester of pregnancy are summarized in the
report form
Survey includes:
Head: skull, brain..
Face
Neck
Thorax: chest, heart.
Abdomen/urinary tract.
Skeletal
Limbs
Placenta, umbilical cord
 Cervix, uterine and adnexa?
Several studies have demonstrated a strong correlation between
short cervical length on transvaginal scan and subsequent preterm
birth. However, several randomized controlled trials that examined the
combination of routine cervical length measurement and subsequent
interventions (cerclage, progesterone) failed to demonstrate
conclusively any cost-effectiveness of such screening programs.

Currently, there is insufficient evidence to recommend routine cervical

length measurements at the mid trimester in an unselected population.

Uterine fibroids and adnexal masses should be documented if they

are likely to interfere with labor.
 USE

THE

FORM!!
ISUOGs website is a great resource for more information:
www.isuog.org