What are Beadlets?

Beadlets are defined as small, free flowing, spherical or semi-spherical solid,

size ranges from 0.5 mm to 1.5 mm, and intended usually for oral administration,

They are manufactured by the agglomerates of fine powders or granules of bulk drugs and excipients using
appropriate processing equipment.

Beadlets can be prepared by many methods, Agitation, compaction, layering, globulation & other new
techniques.
ADVANTAGES :

1. Improved aesthetic appearance of products and also ease marketing.

2. Beadlets are spherical in shape and have greater flow properties.
3. Beadlets can be blended to deliver incompatible bio active ingredients.
4. Beadlets can be used to provide different release profiles at the same or different sites in
Gastro Intestinal Tract.
5. It improves appearance with wide coloration properties.
6. Beadlets can give immediate, extended and as well as controlled release of the targeted
ingredient.
7. Beadlets can be used in dry as well as liquid applications.
8. Pellets disperse freely in GI tract,maximizes drug absorption and minimize local irritation of
the mucosa by certain irritant drugs.
Ideal characteristic of pellets
Spherical shape
Smooth surface for uniform coating
Particle size of pellets should be in the range of 0.5 to 2.0mm
The quantity of the active ingredient in pellets should be maximum in order to maintain size of pellets.
Why Beadlets?
Excellent Stability
Dust free round pellets
Good flow behavior
Easy to dose
Very low hygroscopicity
High bulk Density
Dense uniform surface
Low abrasion
High active ingredient content possible
Drug absorption