How Aspirin is made

Samantha Nicoll Choc Herrera 3401218

Dmaris Gabriela Grijalva Muoz 3007148
Background

80 million pills each year

60 to 650 milligrams

Capsules, caplets, suppositories and

Liquid elixir

Inhibites the synthesis of certain hormones that cause pain and inflammation

Prevents the growth of cells that cause inflammation

History

The active ingredient:

Salicylic acid was found in 1763

Hippocrates used willow leaves to reduce fever

A German chemist found the best way to synthetize the drug

Bayer marketed aspirin in 1899

 In the USA and the UK aspirin is simply the common name for acetylsalicylic acid

The manufacture of aspirin has paralleled advancements in pharmaceutical

manufacturing

The production of hard aspirin requires 4 ingredients:

The active ingredient

Corn starch

Water

Lubricant
The Manufacturing Process

Corn Starch, water and lubricant are added to acetylsalicylic acid to serve as
both a binding agent and diluents.

Aspirin tablets of the same dosage amount are manufactured in batches.

The procedure for manufacturing hard aspirin tablets is known as dry-

granulation or slugging
Steps

Weighing

Mixing

Dry screening

Compression

Testing

Bottling

Packaging