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MUSCULOSKELETAL SYSTEM
The steps that tell cells who they are and what tissues they
should form take place in the control room
Anatomical structures
Provide rigid framework for the trunk and extremities
Locomotor function
Protect vulnerable viscera
Physiological organ
Hemopoietic tissue (RBC, granular leukocytes, platelets)
Reservoir of Ca, Phosphor, Mg, Na
Embryonic development of Bones
Mesoderm mesenchyme (a diffuse cellular tissue that
pluripotent) differentiates into many connective tissue
such as bone, cartilage, ligament, muscle, tendon, fascia.
Ossification
Ossification:
Endochondral (primary center) replacement of
cartilage bones
Endochondral ossification (Growth in length):
Articular cartilage (only in short bones)
Zones in epiphyseal
plate:
Resting cartilage
Young proliferative cartilage
Maturing cartilage
Calcifying cartilage
Epiphyseal Plate (3)
Calcitonin actions :
Produce by thyroid gland
stimulated by hypercalcemia
inhibited by hypocalcemia
decrease bone resorption,
surpress osteoclastic activity
(th/ of Paget disease and
osteoporosis)
Joint and articular cartilage
Classification
Similarity : Differences :
Derived from mesenchym
Bone:
Have cells embedded in
Collagen type I
lacuna and have matrix
Highly vascular
Matrix are calcified
Cartilage:
Collagen type II
Poorly vascular
Structure and function of synovial membrane
Type I Type II
Slow twitch Fast-twitch
Slow oxidative Glycolytic
High repetition For activities that require
Low-load endurance speed and power
activities red fibre
white fibre
Prefer oxidative chain as
main energy source
TENDON & LIGAMENTS
Profile
Composed of dense
connective tissue
abundant in nonextensile
collagen (type I) fibres
known as fibrous connective
tissue
Remarkable tensile strength
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