Professional Documents
Culture Documents
CAESAR AYUDI
dr. WIDODO Sp.PD KGH, FINASIM
SMF ILMU PENYAKIT DALAM
TOPICS
Background
Definition
Causes
Clinical Findings
Labs and Imaging
Complications
Treatment
Prognosis
BACKGROUND
The term end-stage renal disease represents a stage of CKD where the accumulation of
toxins, fluid, and electrolytes normally excreted by the kidneys results in the uremic
syndrome.
More than 10% of U.S. adults may have CKD
More than 20 million, aged 20 years or older
The most frequent cause of CKD in North America and Europe is diabetic
nephropathy,most often secondary to type 2 diabetes mellitus
DEFINITION
According NKF-K/DOQI
Glomerular Chronic
Disease Rejection
DM I
Tubulointerstitial Drug Toxicity
DM II Disease Glomerulopathy
Cystic Disease Transplant
HT,
microangiopathy
PATHOPHYSIOLOGY OF CKD
Tubulus damage
Hyperfiltration
Nephrosclerosis Interstitial
Hypertrophy
inflammation
CLINICAL FINDINGS
Basicly, symptoms of CKD related to decline of renal functions
LABS
Elevation of BUN and creatinine serum
Hematologic abnormalities
Hemostasis abnormalities
IMAGING
HYPERKALEMIA
ACID-BASE DISORDER
CARDIOVASCULAR
HEMATOLOGIC
NEUROLOGIC
ENDOCRINE DISORDERS
TREATMENT
Detection and
Management of
treatment of
Anemia
infection
Pay attention to the
treatment and
patient safety Dialysis
(medicine)
Transplantation
CKD-PROGNOSIS