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Iodine and The Thyroid: Mark Vanderpump UK National Coordinator Iodine Global Network
Iodine and The Thyroid: Mark Vanderpump UK National Coordinator Iodine Global Network
Mark Vanderpump
UK National Coordinator
Iodine Global Network
Thyroid gland
Thyroid hormone target tissues
Retina Brain
Liver Gut
Generously supported by
Clinical Endocrinology Trust
UI concentrations in UK schoolgirls
(n=737)
%
Median 80µg/L
Summer
Urine samples n=537
Median 76µg/L
Aberdeen 82µg/L
Winter
Urine samples n=200
Median 95µg/L Belfast 62µg/L Newcastle/
Gateshead 75µg/L
P<0.001
Birmingham 75µg/L
Exeter 83µg/L
UK iodine survey: Milk intake
National iodine status based on
UI in schoolchildren
(WHO 2011)
Impact of mild-moderate iodine
deficiency
• Hypothyroxinaemia not raised serum TSH
• Maternal T4 crucial before 13 weeks gestation
• Children born to women may have psycho-
neurological deficits and delayed mental
function compared with controls
• Functional consequences in older children is
unclear
How to correct iodine deficiency?