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DEPART. OF FARMACOLOGY,
MEDICAL FACULTY, MOSLEM
UNIVERSITY
● Number of drugs available: limited
● Difficult to obtain selective toxicity to virus:
replication of virus is the normal synthetic process
of the cell
● Several virus-specific replication steps → the site
of action of effective antiviral drugs.
● Antiviral drugs are relatively ineffective: many cycle
of viral replication occur during the incubation time.
● Some viruses become latent within the cell: no
current antiviral drugs can eradicate them.
● Emergence of drug resistance viral mutans.
■ Inhibition of Viral Nucleic Acid Synthesis
■ Inhibition of Cleavage of Precursor
Polypetides
■ Inhibition of Viral Protein Synthesis
■ Inhibition of Release of Virus