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Place of expression

V2 receptor(also called Arginine vasopressin


receptor) is expressed in following places :

 Expressed in membrane of the cells in the


basolateral membrane of late DCT and collecting
duct.
 Also expressed outside the kidney, and, when
stimulated ,can cause the release of von
willebrand factor from the vasculature.
Fusion of vesicle containing
ADH binds to V2 receptor,
aquaporine 2 to luminal
a GPCR
membrane

Activation of protein
kinase A
Activation of adenylate
cyclase
Reference

• Medical physiology by Walter .F. Boron


• Textbook of medical physiology Guyton &Hall
• Wikipedia

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