Mode of Transmission

• Sexual contact with an infected person (vaginal,

anal)
• Kissing (oral)
• Breastfeeding by mothers with primary or
secondary lesions
• Contact with open lesion of infected person
• Exposure to infected blood
• Congenital Infection "in utero infection"
 PATHOGENIC MICROORGANISM

Treponema Pallidum
 TROPONEMA PALLIDUM

Intact mucous membranes / skin lesions

Circulatory / All organs

Incubation
period
± 3 Weeks
Syphilis Macula, papula

Sign and Symptoms

 SIGN and SYMPTOMS

1. Primary syphilis (SI)

2-4 week
- a surface to erosion - ulcer. lesions
2. Secondary Syphilis (S II)
Arise 6-8 weeks after SI,
1/3 of cases are accompanied by SI
S II can last up to 9 months
- anorexia
- weight loss
- fatigue-weakness
- headache
- high fever
- arthralgia
3. Tertiary Syphilis (S III)
is the final stages in the natural
history of the disease.
Infected do not exhibit sign and
symptoms.
1. Antibiotics
- Weaken bacteria
- Increase endurance that syphilis is not
getting worse

2. Penicillin Procain
- (Injected). weaken bacteria

3. Azithromycin
Its function is similar to penicillin procain
- Weaken the syphilis bacteria.
Penicillin
Procain
Azithromycin
Serological Test
- antibodies reacting with the appropriate
antigen
- Assist to diagnose of disease
- Knowing the success of vaccination

Blood Test
1. Screening tests:
- determine positive / negative syphilis