LOGO

IMUNITAS ADAPTIF
(SPESIFIK/DIDAPAT/ACQUIRED)

Riandini Aisyah, M.Sc

Bagian Biomolekuler dan Imunologi
Lymphoid Organ
Adaptive immune system : the main actors are
lymphocytes
Lymphocytes :
1. T lymphocyte (B cell)
2. B lymphocyte (T cell)
T cell effector
Activated B cell
Immunoglobulin distribution and
function
Phase of Immune response
Antigen recognition by T cell
T cell activation
T cell development
Positive and negative selection
Positive selection
Negative selection
Negative selection
The role of effector T cell
Naïve T cell activation
Signal needed for CD8 activation
Prevention immune response to self antigen
Different molecules deal to
pathogen classes
CD8 CTL and apoptosis
Macrophage activation by Th1
 B cell development and activation

B cells develop in bone marrow and migrate to the

peripheral lymphoid organ, and activated by
antigen2
B cell : negative and positive
selection
B cell activation
Link recognition between Th cell – B
cell
Types of Ab released by plasma cell
LOGO Refferences :
Susilowati, R, Paramita, DK, Purnomosari, D. 2013. Kursus
Immunolgi. Fakultas Kedokteran UGM>