an acceptable way? Kho maaf kalo inggrisnya aneh, sama nomer 2 aku ga tau 1. were the control representative of a defined population (geographically and/or temporally)? • The researcher had exclude several mothers who were not speaking Norwegian, because that can be they were temporally population. 2. Was there something special about the controls? • Ratio case:control = 1:2 in cleft lip with or without cleft palate case:control = 1:4 in cleft palate only 3. was the non-response high? Could non- respondents be different in any way? • The non response was low, and the response was high. The journal explain that folic acid can reduce the risk of cleft lift, but it was not explain folic acid totally diminished the cleft lips. 4. are they matched, population based or randomly selected? • Yes, they are matched and randomly selected from the data. • 5. was there a sufficient number of controls selected? • No. if we count the number of case and controls, then count into ratio, the results are different.