MURDER MYSTERY LAB

BY: Joseph A, Juan H, Cristian T, Stephanie M, and Brian G.

INTRODUCTION
Captain Relish invited a couple people to have a celebration party. They
were Sam Stubs, Glen Glendora, Norma Nanny, Fred Fleckstone, and
Theresa Thyme. At 7:35 p.m. the power went out and Captain Relish was
mysteriously dead at 7:36 p.m. He was stabbed in the back of the neck.
When the police arrived, they discovered 2 types of blood. One was
discovered to the Captain Relish’s and the other was the killers’.
Evidence Discovered at Crime Scene
2 blood samples were discovered at the crime scene. They found no trace of Marfan syndrome
in either blood sample, but found a low level of neurotransmitters in each.

Blood Sample #1 Blood Sample #2

● Female’s blood ● Male’s blood(Captain Relish’s)

● Type A blood ● Type O blood
● DNA Sequence - GATTCCCAACGG ● DNA Sequence - GATTCCGAACGG
● Has Triple X Syndrome ● Has XYY Syndrome
Blood Sample #1 Blood Sample #2
Characters
1. Theresa Thyme

● Type A Blood - IA IO
● DNA Sequence - GATTCCCAACGG
● Doesn’t have Marfan Syndrome
● Doesn’t have Huntington’s Disease
● Has Down Syndrome
Characters
2. Norma Nanny

● Type A blood - IA IO
● DNA Sequence - GATTCCCAACGG
● Doesn’t have Marfan Disease
● Has Huntington Disease
● Has Triple X syndrome
Characters
3. Glen Glendora

● Type A Blood - IA IO
● DNA Sequence - GATTCCGAACGG
● Doesn’t have Marfan Disease
● May carry Huntington Disease
● No chromosomal disorder
Characters
4. Fred Fleckstone

● Type B blood - IB IO
● DNA Sequence - GATTCCCAACGG
● Has Marfan syndrome
● Doesn’t have Huntington disease
● No chromosomal disorders
Characters
5. Sam Stubs

● Type AB blood - IA IB
● DNA Sequence - GATTCCGAACGG
● Doesn’t have Marfan syndrome
● May have Huntington Disease
● Has XYY Syndrome
Characters
6. Captain Relish

● Type O blood - IO IO
● DNA Sequence - GATTCCGAACGG
● Doesnt have Marfan syndrome
● Has Huntington Disease
● Has XYY syndrome
Diseases and Disorders
1. Marfan Syndrome
A genetic disorder that affects connective tissue. It is
caused by a defect in the gene that tells the body how to
make fibrillin-1. This causes the body to overproduce the
protein TGF-beta(a protein that controls cell growth). This
causes the problems with the connective tissue. Symptoms
include tallness, back pain, long fingers, arms, and legs,
sunken chest, etc.. It can affect many parts of the body,
such as the heart,bones, joints, eyes, and blood vessels.
Treatment is available, such as medications to keep blood
pressure low, eye glasses or contact lenses, and surgery.
About 1 out of 5000 people have the disorder.
2. Huntington’s Chorea
A disorder that causes the death of brain cell. Each human
has 2 Huntingtin genes. Part of these genes is a repeated
section that is called a trinucleotide repeat. Although the
length varies from person to person, if the section reaches a
certain intensity, it produces a mutated form of the
Huntingtin protein, which causes the disease’s symptoms.
Symptoms include uncontrolled movements, emotional
problems, loss of cognition, etc.. Treatment is available,
such as drugs, physical therapy, and talk therapy. It affects
about 3-7 people out of 100,000.
Diseases and Disorders
3. Achondroplasia
It is a genetic disorder that is the most common cause of
dwarfism. It is caused by a mutation in the fibroblast
growth factor receptor 3. Usually, this has a negative
regulatory effect on bone growth, but the mutated form
does, thus causing severely short bones. Symptoms include
short nature, shortening of limbs, short fingers and toes,
large head with prominent forehead, etc.. It is autosomal
dominant. There is no consistent treatment for the
disorder, but gene therapy has proven to help a bit. It
affects every 1 in 25,000 people.
4. Klinefelter’s Syndrome
It is a chromosomal disorder that affects sterility, It is
caused as a result of 2 or more X chromosomes. The extra
chromosome is caused by a nondisjunction during meiosis
1. Symptoms include less body hair, smaller genitals, breast
growth, and less interest in sex. It is neither dominant or
recessive due to it not being inherited. Treatment is
available, such as hormone therapy, surgery, behavioral
therapy, etc.. It affects every 1 in 500-1000 people.
Diseases and Disorders
5. Triple X Syndrome
It is a disorder in which a female carries an extra x
chromosome in each of their cells. It is caused by
nondisjunction during the formation of reproductive cells.
There can be no symptoms, but some may experience
unusual tallness, delayed development, small head, poor
muscle tone, etc.. There is no mode of inheritance because
it cannot be inherited. In most cases, no treatment is
needed. But those with development issues can take speech
therapy, physical therapy, and counseling. It occurs in 1 in
every 2000 females.
6. XYY Syndrome
It is a condition in which a male possess an extra Y
chromosome. It is caused by nondisjunction during the
formation of sperm cells. Symptoms may include an
increased growth velocity from early childhood, severe
acne in few cases, and learning difficulties. There is no
mode of inheritance because it cannot be inherited. It can’t
be cured, but treatment is available, such as speech therapy,
occupational therapy, etc.. It affects every 1 in 1000 males.
Diseases and Disorders
7. Down Syndrome

A genetic disorder that causes developmental and

intellectual delays. It is caused by nondisjunction during
the development of egg or sperm cells. Symptoms include
intellectual disabilities, short stature, slanted eyes, poor
immune function, congenital heart defect, etc.. The 21st
chromosome is affected due to their being an extra one.
There is no mode of inheritance because it cannot be
inherited. Treatment consists of speech therapy, physical
therapy, support groups special educators, etc.. It occurs in
every 1 in 1000 births
 Information Sheet
Name of Blood Type DNA Sequence Marfan Syndrome Huntington Chromosomal
Person Disease Disorder

Theresa Thyme Type A Blood GATTCCCAACGG Not a carrier Not a carrier Down Syndrome

Norma Nanny Type A Blood GATTCCCAACGG Not a carrier Possible carrier Triple X
Syndrome

Glen Glendora Type A Blood GATTCCGAACGG Not a carrier Possible carrier None

Fred Type B Blood GATTCCCAACGG Has disorder Not a carrier None

Fleckstone

Sam Stubs Type AB Blood GATTCCGAACGG Not a carrier Possible carrier XYY Syndrome

Captain Relish Type O Blood GATTCCGAACGG Not a carrier Has disorder XYY Syndrome
Conclusion
We’ve concluded that Norma Nanny is the Norma’s motive to kill Captain Relish may have
murderer been because he was Thomas Sandstone, who
killed many people in her family, and she may have
● Blood Sample #1 is female wanted to avenge those he’s killed,
● Blood Sample #1 and Norma Nanny both
show Triple X syndrome in their karyotypes
● Both are type A blood
● DNA Sequences are the same
● Blood Sample #1 shows low level of
neurotransmitters, which is caused by
Huntington Disease, which Norma may
have