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  • Andrographolide Enhances TRAIL Induced Apoptosis Via P53-Mediated Death

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    Gufron Alifi
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    Andrographolide enhances TRAIL-induced apoptosis in bladder cancer cells by upregulating death receptors through a p53-mediated mechanism and suppressing the NF-κB pathway. Andrographolide works synergistically with TRAIL to induce apoptosis in bladder cancer cells by increasing expression of death receptors and decreasing expression of anti-apoptotic proteins regulated by NF-κB. The study suggests that combining andrographolide with TRAIL may be a potential therapeutic strategy for bladder cancer.

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    Andrographolide Enhances TRAIL Induced Apoptosis via p53-Mediated Death

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    Andrographolide Enhances TRAIL Induced Apoptosis via p53-Mediated Death

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    Andrographolide enhances TRAIL-induced apoptosis in bladder cancer cells by upregulating death receptors through a p53-mediated mechanism and suppressing the NF-κB pathway. Andrographolide works synergistically with TRAIL to induce apoptosis in bladder cancer cells by increasing expression of death receptors and decreasing expression of anti-apoptotic proteins regulated by NF-κB. The study suggests that combining andrographolide with TRAIL may be a potential therapeutic strategy for bladder cancer.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    9 views2 pages

    Andrographolide Enhances TRAIL Induced Apoptosis Via P53-Mediated Death

    Uploaded by

    Gufron Alifi
    Andrographolide enhances TRAIL-induced apoptosis in bladder cancer cells by upregulating death receptors through a p53-mediated mechanism and suppressing the NF-κB pathway. Andrographolide works synergistically with TRAIL to induce apoptosis in bladder cancer cells by increasing expression of death receptors and decreasing expression of anti-apoptotic proteins regulated by NF-κB. The study suggests that combining andrographolide with TRAIL may be a potential therapeutic strategy for bladder cancer.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 2

    Andrographolide Enhances TRAIL

    Induced Apoptosis via p53-Mediated


    Death Receptors Up-Regulation and
    Suppression of the NF-кB Pathway in
    Bladder Cancer Cells

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