SODIUM NITROPRUSSIDE,

Na2[Fe(CN)5NO] • 2H2O

ASSIGNMENT 1 :
COORDINATION COMPLEX IN DAILY LIFE
NAME SITI FATIMAH NAZLIA BINTI RUSLAN
MATRIC NUMBER D20171078199
LECTURER’S NAME PROFESOR MADYA DR. NORHAYATI BINTI HASHIM
LECTURE GROUP A
 STRUCTURE
Sodium nitroprusside is disodium pentacyanonitrosylferrate(2-) dihydrate, a
hypotensive agent whose structural formula is:
PHYSICAL PROPERTIES

This red coloured sodium salt dissolve in

water or ethanol to give solutions containing
that free complex dianion [Fe(CN)₅NO]²¯
 Molecular
Weight :
297.951 g/mol

CHEMICAL
PROPERTIES

Density : Soluble in
1.72 g/𝑐𝑚3 Water
 Control High
blood pressure

USE OF SODIUM
NITROPRUSSIDE

Severe
Control bleeding
congestive heart
during surgery
failure
 FUNCTION OF SODIUM NITROPRUSSIDE
 Control High Blood Pressure
This NO works as vasodilator,
Once in the body, sodium
causing the muscles
nitroprusside is quickly As the blood vessels expand,
surrounding blood vessels to
broken down nitric oxide, blood pressure drops.
relax, allowing the blood
powerful vasodilator.
vessels themselves to expand.

 Severe congestive Heart failure

NO enters the muscle cells in the Lowering the blood pressure helps
walls of the blood vessels and to reduce the workload of the
causes them to relax. heart.
 Geometry of sodium
nitroprusside
 Nitroprusside is a complex anion that features an octahedral iron(III) centre.
Surrounded with five tightly bound cyanide ligand.
 Consequently, iron is assigned an oxidation state of 2+.
The iron center has a diamagnetic low spin d⁶ electron configuration.
The anion possesses idealized C4v symmetry.
 REFERENCES
 (2017, January). Sodium Nitropress Nitroprusside. RxList.
Retrieved from : https://www.rxlist.com/sodium-nitropress-nitroprusside- drug.htm#medguide
 (2015, May). Sodium nitroprusside. Netdoctor.
Retrieved from : https://www.netdoctor.co.uk/medicines/heart-blood/a7546/sodium-
nitroprusside/
 Furman, B. (2018). Sodium nitroprusside. Science Direct.
Retrieved from : https://www.sciencedirect.com/topics/neuroscience/sodium- nitroprusside
 Loana, D. (2018, May). What is the role of sodium nitroprusside in the treatment of acute heart
failure?. Medscape.
Retrieved from :https://www.medscape.com/answers/163062-86359/what-is-the-role-of-
sodium-nitroprusside-in-the-treatment-of-acute-heart-failure#qna
 Drover, D. R. (2015). Evaluation of sodium nitroprusside for controlled hypotension in children
during surgery. PubMed.
Retrieved from :https://www.ncbi.nlm.nih.gov/m/pubmed/26217225/