PANCREATITIS

Drugs and Treatment

Acute Pancreatitis
• Medical management
– All oral intake is withheld to inhibit pancreatic stimulation and secretion of
pancreatic enzymes
– H2 antagonist may be prescribed to decrease HCL secretion.
– Antiemetic agents may be prescribed to prevent vomiting
– Biliary drainage
• Pain management
– Meperidine (Demerol is often prescribed as it is less likely to cause spasm
in the sphincter of Oddi)
• Intensive care
– IV fluids
– Insulin may be prescribed if hyperglycemia occurs
• Postacute management
– Oral feedings low in fat and protein
– Avoid caffeine and alcohol
– Antacids may be used when acute pancreatitis begins to resolve
 Drugs and Treatment
Chronic Pancreatitis
• Medical Management
 Treatment is directed towards managing acute
attacks and relieving pain
• Nonsurgical management
 Endoscopy
 Management of pain (same as acute pancreatitis)
• Surgical management
 Pancreaticojejunostomy
 Diagnostic test
Acute Pancreatitis

• Serum amylase and lipase

• Complete blood count
• Endoscopic retrograde
cholangiopancreatography
• Stool examination
• X-ray
• Ultrasound
 Diagnostic test
Chronic Pancreatitis

• Endoscopic retrograde
cholangiopancreatography
• Magnetic resonance imaging
• Ultrasound
• Glucose tolerance test