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CLINICAL PHARMACOLOGY

dr. Kartini Lidia,MSc

Department of Pharmacology and


Therapeutics
Nusa Cendana University
2015

SYSTEMS PHARMACOLOGY
Drugs acting on the sympathetic nervous
system
Drugs acting on the parasympathetic nervous
system
Nicotine
Biogenic Amines
Vasodilators
Inhibitors of the renin angiotensin
aldosterone system
Drugs acting on smooth muscle
Cardiac drugs
Antianemic
Antithrombotics
Plasma Volume Expanders
Drugs used in hyperlipoproteinemias
Diuretics
Drugs for the treatment of peptic ulcer
Laxative
Antidiarrheals
Drugs acting on the motor system
Drugs for the suppresion of pain

Antipyretic analgesic
Non steroidal anti inflammatory drugs
Local anesthetics
Opioid
General anesthetics
Psychopharmacologicals
Hormones
Antibacterial dugs
Anti fungal drugs
Antiviral drugs
Antiparasitic drugs
Anticancer drugs
Immune modulators
Antidotes

The clinician usually wants to maintain steady-state


concentrations of a drug within a therapeutic window associated
with therapeutic efficacy and a minimum of toxicity for a given
agent.

drug combination

Synergism (cooperation)
Summacy (addictive effects) : 1+1=2
Potentiation : 1+1=3

Antagonism (eliminating each other)

drug of choice

Type of disease
Severity of illness
Physical condition

Socio-economics

THANK YOU

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