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    Delta Rosalina Nainggolan
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    Bioactive glass is a synthetic biomaterial that bonds to living bone. It can be synthesized through a sol-gel process involving low temperatures and a mixture of oxides to produce high purity nano-sized glass. Bioactive glass has several applications including use as a graft material to repair bone defects, as an endosseous implant where it promotes normal tissue healing and new bone formation, and as a remineralizing agent to occlude dentinal tubules and manage tooth sensitivity. It also functions as an antibacterial agent and can be used to deliver drugs and growth factors to promote bone growth. In bone tissue engineering, bioactive glass composites have been shown to facilitate cell growth and mineralization.

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    Bioactive glass is a synthetic biomaterial that bonds to living bone. It can be synthesized through a sol-gel process involving low temperatures and a mixture of oxides to produce high purity nano-sized glass. Bioactive glass has several applications including use as a graft material to repair bone defects, as an endosseous implant where it promotes normal tissue healing and new bone formation, and as a remineralizing agent to occlude dentinal tubules and manage tooth sensitivity. It also functions as an antibacterial agent and can be used to deliver drugs and growth factors to promote bone growth. In bone tissue engineering, bioactive glass composites have been shown to facilitate cell growth and mineralization.

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    20 views13 pages

    Bioactive Glass

    Uploaded by

    Delta Rosalina Nainggolan
    Bioactive glass is a synthetic biomaterial that bonds to living bone. It can be synthesized through a sol-gel process involving low temperatures and a mixture of oxides to produce high purity nano-sized glass. Bioactive glass has several applications including use as a graft material to repair bone defects, as an endosseous implant where it promotes normal tissue healing and new bone formation, and as a remineralizing agent to occlude dentinal tubules and manage tooth sensitivity. It also functions as an antibacterial agent and can be used to deliver drugs and growth factors to promote bone growth. In bone tissue engineering, bioactive glass composites have been shown to facilitate cell growth and mineralization.

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    © All Rights Reserved
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    of 13

    BIOACTIVE GLASS

    MATERIAL
    GROUP 4
    FAHDLY AWALUDDIN 105117017 DIAH KEMALA MUTMAINAH 105117003
    DELTA ROSALINA 105117006 NURUL NOVIANTI 105117010
    ATHIRAH NUR S 105117027 DYAS DWI S 105117006
    WHAT
    IS BIO ACTIVE GLASS ?

    Orthopedi

    hydroxyapatite

    Si, Ca, P, and Na Ion


    HOW TO SYNTHESIS ?

    Low Temperature
    Mixture of Oxides
    SOL-GEL

    High Purity Bioactive


    Nano Size
    Glass
    APPLICATIONS
    BIOACTIVE GLASS
    1. BIOGLASS AS A GRAFT MATERIAL

     repair massive bone defects caused by


    disease and trauma, a bone grafting
    procedure is required
     The porous structure supports tissue
    in/on growth and improves implant
    stability by biologic fixation
    2. BIOGLASS AS ENDOSSEOUS IMPLANT

     Infectionless normal tissue healing with new


    bone formation as sighted in radiographs
    made bioglass a highly biocompatible
    innovation
    3. BIOGLASS AS REMINERALIZING AGENT

     characteristic osteogenic
    activity of bioactive glass made
    it worth its trial in management
    of hypersensitivity by occluding
    dentinal tubules
    4. BIOGLASS AS ANTIBACTERIAL AGENT

    Bioglass is an efficient antibacterial


    agent and its antibacterial effect was
    attributed to its alkaline nature
    5. BIOGLASS IN DELIVERY OF DRUGS AND GROWTH FACTORS

     Vancomycin on bioglass carrier has


    been tested for treating osteomyelitis
    with success.
     The fast-acting anti-inflammatory
    drug ibuprofen was released in the
    first 8 hours when immersed in
    simulated body fluid
    6. BIOGLASS IN BONE TISSUE ENGINEERING

     biocomposite nanofibers and


    nanohydroxyapatite were naturally very
    porous, which in turn facilitated good
    cell occupancy, vascularity, movement of
    nutrients, and metabolic waste products
     produced increased osteoblast
    proliferation and differentiation. This
    system helped the human fetal
    osteoblasts to adhere, migrate,
    proliferate, and mineralize into bone
    THANK
    YOU

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